4USG
Crystal structure of PC4 W89Y mutant complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 | polymer | 66 | 7761.0 | 2 | UniProt (P53999) Pfam (PF02229) | HOMO SAPIENS (HUMAN) | POSITIVE COFACTOR 4, PC4, SUB1 HOMOLOG, P14 |
| 2 | C (C) | 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP *TP*TP*TP*TP*TP*G)-3' | polymer | 20 | 6063.9 | 1 | HOMO SAPIENS | DT19G1 | |
| 3 | D, E, F (A, B, C) | water | water | 18.0 | 128 | Chemie (HOH) |
Sequence modifications
A, B: 63 - 127 (UniProt: P53999)
| PDB | External Database | Details |
|---|---|---|
| Ala 62 | - | expression tag |
| Tyr 89 | Trp 89 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 21585.9 | |
| All* | Total formula weight | 21585.9 |
