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4GUS
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BU of 4gus by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P3221
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
7Y76
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BU of 7y76 by Molmil
SIT1-ACE2-BA.5 RBD
分子名称: 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shen, Y.P, Li, Y.N, Zhang, Y.Y, Yan, R.H.
登録日2022-06-21
公開日2023-01-04
最終更新日2023-02-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structures of ACE2-SIT1 recognized by Omicron variants of SARS-CoV-2.
Cell Discov, 8, 2022
4LEX
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BU of 4lex by Molmil
Unliganded crystal structure of mAb7
分子名称: FAB HEAVY CHAIN, FAB LIGHT CHAIN
著者Murray, J.M, Mukund, S.
登録日2013-06-26
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
J.Biol.Chem., 288, 2013
3MTL
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BU of 3mtl by Molmil
Crystal structure of the PCTAIRE1 kinase in complex with Indirubin E804
分子名称: (2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}, Cell division protein kinase 16
著者Krojer, T, Sharpe, T.D, Roos, A, Savitsky, P, Amos, A, Ayinampudi, V, Berridge, G, Fedorov, O, Keates, T, Phillips, C, Burgess-Brown, N, Zhang, Y, Pike, A.C.W, Muniz, J, Vollmar, M, Thangaratnarajah, C, Rellos, P, Ugochukwu, E, Filippakopoulos, P, Yue, W, Das, S, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-06-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and inhibitor specificity of the PCTAIRE-family kinase CDK16.
Biochem.J., 474, 2017
5EIG
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BU of 5eig by Molmil
Engineered human cystathionine gamma lyase (E59T, E339V) to deplet cysteine
分子名称: CYSTEINE, Cystathionine gamma-lyase, SULFATE ION
著者Yan, W, Zhang, J.
登録日2015-10-29
公開日2016-11-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Systemic Depletion of Serum L-Cyst(e)ine with an Engineered Human Enzyme Mediates Potent Induction of ROS and Cancer Ablation
To Be Published
4GUR
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BU of 4gur by Molmil
Crystal structure of LSD2-NPAC with H3 in space group P21
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
7XC7
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BU of 7xc7 by Molmil
Cryo-EM structure of a bacterial protein complex
分子名称: CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ...
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-23
公開日2022-11-16
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
7X7A
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BU of 7x7a by Molmil
Cryo-EM structure of SbCas7-11 in complex with crRNA and target RNA
分子名称: RAMP superfamily protein, RNA (33-MER), ZINC ION
著者Yu, G, Wang, X, Deng, Z, Zhang, H.
登録日2022-03-09
公開日2022-11-16
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
Nat Microbiol, 7, 2022
4LF3
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BU of 4lf3 by Molmil
Inhibitory Mechanism of an Allosteric Antibody Targeting the Glucagon Receptor
分子名称: Fab heavy chain, Fab light chain, Glucagon receptor
著者Murray, J.M, Mukund, S.
登録日2013-06-26
公開日2013-11-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.735 Å)
主引用文献Inhibitory mechanism of an allosteric antibody targeting the glucagon receptor.
J.Biol.Chem., 288, 2013
6M17
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BU of 6m17 by Molmil
The 2019-nCoV RBD/ACE2-B0AT1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, R.H, Zhang, Y.Y, Li, Y.N, Xia, L, Guo, Y.Y, Zhou, Q.
登録日2020-02-24
公開日2020-03-11
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2.
Science, 367, 2020
4GUT
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BU of 4gut by Molmil
Crystal structure of LSD2-NPAC
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1B, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GU1
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BU of 4gu1 by Molmil
Crystal structure of LSD2
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.939 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
4GUU
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BU of 4guu by Molmil
Crystal structure of LSD2-NPAC with tranylcypromine
分子名称: Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, ZINC ION, ...
著者Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Xu, Y.
登録日2012-08-29
公開日2013-01-16
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation
Mol.Cell, 49, 2013
5X83
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BU of 5x83 by Molmil
Structure of DCC FN456 domains
分子名称: Netrin receptor DCC
著者Finci, F.I, Xiao, J, Wang, J.
登録日2017-02-28
公開日2017-09-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC
Protein Cell, 8, 2017
6JC8
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BU of 6jc8 by Molmil
Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Glu
分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, CrmG, GLYCEROL
著者Xu, J, Liu, J.
登録日2019-01-28
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020
2UP1
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BU of 2up1 by Molmil
STRUCTURE OF UP1-TELOMERIC DNA COMPLEX
分子名称: DNA (5'-D(P*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), PROTEIN (HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1)
著者Ding, J, Hayashi, M.K, Krainer, A.R, Xu, R.-M.
登録日1998-07-10
公開日1999-11-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA.
Genes Dev., 13, 1999
6JKM
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BU of 6jkm by Molmil
Crystal structure of BubR1 kinase domain
分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ...
著者Lin, L, Ye, S, Huang, Y, Liu, X, Zhang, R, Yao, X.
登録日2019-03-01
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 29, 2019
6J75
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BU of 6j75 by Molmil
Structure of 3,6-anhydro-L-galactose Dehydrogenase
分子名称: Aldehyde dehydrogenase A
著者Li, P.Y, Wang, Y, Chen, X.L, Zhang, Y.Z.
登録日2019-01-17
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.695 Å)
主引用文献3,6-Anhydro-L-Galactose Dehydrogenase VvAHGD is a Member of a New Aldehyde Dehydrogenase Family and Catalyzes by a Novel Mechanism with Conformational Switch of Two Catalytic Residues Cysteine 282 and Glutamate 248.
J.Mol.Biol., 432, 2020
6FWJ
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BU of 6fwj by Molmil
Structure of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with alpha-Glc-1,3-(1,2-anhydro-carba-mannosamine) and alpha-1,2-mannobiose
分子名称: (1~{R},2~{R},3~{R},4~{R},6~{R})-4-(hydroxymethyl)-7-azabicyclo[4.1.0]heptane-2,3-diol, ACETATE ION, Glycosyl hydrolase family 71, ...
著者Sobala, L.F, Speciale, G, Hakki, Z, Fernandes, P.Z, Raich, L, Rojas-Cervellera, V, Bennet, A, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Lu, D, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J.
登録日2018-03-06
公開日2019-09-18
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献An Epoxide Intermediate in Glycosidase Catalysis.
Acs Cent.Sci., 6, 2020
3NB6
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BU of 3nb6 by Molmil
Crystal structure of Aquifex aeolicus peptidoglycan glycosyltransferase in complex with Methylphosphoryl Neryl Moenomycin
分子名称: Penicillin-binding protein 1A
著者Sliz, P, Yuan, Y, Walker, S, Kahne, D.
登録日2010-06-02
公開日2011-05-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Functional and structural analysis of a key region of the cell wall inhibitor moenomycin.
Acs Chem.Biol., 5, 2010
3S28
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BU of 3s28 by Molmil
The crystal structure of sucrose synthase-1 in complex with a breakdown product of the UDP-glucose
分子名称: 1,5-anhydro-D-arabino-hex-1-enitol, 1,5-anhydro-D-fructose, MALONIC ACID, ...
著者Zheng, Y, Garavito, R.M.
登録日2011-05-16
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
3NJB
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BU of 3njb by Molmil
Crystal structure of enoyl-coa hydratase from Mycobacterium smegmatis, iodide soak
分子名称: Enoyl-CoA hydratase, IODIDE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2010-06-17
公開日2010-07-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SAD phasing using iodide ions in a high-throughput structural genomics environment.
J.Struct.Funct.Genom., 12, 2011
2EWG
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BU of 2ewg by Molmil
T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate
分子名称: (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), MAGNESIUM ION, S-1,2-PROPANEDIOL, ...
著者Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E.
登録日2005-11-03
公開日2006-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
J.Am.Chem.Soc., 128, 2006
3S27
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BU of 3s27 by Molmil
The crystal structure of sucrose synthase-1 from Arabidopsis thaliana and its functional implications.
分子名称: MALONIC ACID, POTASSIUM ION, SULFATE ION, ...
著者Zheng, Y, Garavito, R.M.
登録日2011-05-16
公開日2011-08-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献The Structure of Sucrose Synthase-1 from Arabidopsis thaliana and Its Functional Implications.
J.Biol.Chem., 286, 2011
2I19
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BU of 2i19 by Molmil
T. Brucei farnesyl diphosphate synthase complexed with bisphosphonate
分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, [2-(PYRIDIN-2-YLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
著者Cao, R, Mao, J, Gao, Y, Robinson, H, Odeh, S, Goddard, A, Oldfield, E.
登録日2006-08-13
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes.
J.Am.Chem.Soc., 128, 2006

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