2EWG
T. brucei Farnesyl Diphosphate Synthase Complexed with Minodronate
Summary for 2EWG
| Entry DOI | 10.2210/pdb2ewg/pdb |
| Descriptor | farnesyl pyrophosphate synthase, MAGNESIUM ION, (1-HYDROXY-2-IMIDAZO[1,2-A]PYRIDIN-3-YLETHANE-1,1-DIYL)BIS(PHOSPHONIC ACID), ... (5 entities in total) |
| Functional Keywords | protein-bisphosphonate complex, transferase |
| Biological source | Trypanosoma brucei |
| Total number of polymer chains | 2 |
| Total formula weight | 89969.88 |
| Authors | Cao, R.,Mao, J.,Gao, Y.,Robinson, H.,Odeh, S.,Goddard, A.,Oldfield, E. (deposition date: 2005-11-03, release date: 2006-10-31, Last modification date: 2024-02-14) |
| Primary citation | Mao, J.,Mukherjee, S.,Zhang, Y.,Cao, R.,Sanders, J.M.,Song, Y.,Zhang, Y.,Meints, G.A.,Gao, Y.G.,Mukkamala, D.,Hudock, M.P.,Oldfield, E. Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. J.Am.Chem.Soc., 128:14485-14497, 2006 Cited by PubMed: 17090032DOI: 10.1021/ja061737c PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.48 Å) |
Structure validation
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