5L4F
| Crystal Structure of Human Transthyretin in Complex with 2,6-Dinitro-p-cresol (DNPC) | 分子名称: | 2,6-Dinitro-p-cresol, SODIUM ION, Transthyretin | 著者 | Grundstrom, C, Hall, M, Zhang, J, Olofsson, A, Andersson, P, Sauer-Eriksson, A.E. | 登録日 | 2016-05-25 | 公開日 | 2016-10-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structure-Based Virtual Screening Protocol for in Silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin. Environ. Sci. Technol., 50, 2016
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2L54
| Solution structure of the Zalpha domain mutant of ADAR1 (N43A,Y47A) | 分子名称: | Double-stranded RNA-specific adenosine deaminase | 著者 | Zhao, J, Pervushin, K, Feng, S, Droge, P. | 登録日 | 2010-10-24 | 公開日 | 2011-01-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Alternate rRNA secondary structures as regulators of translation Nat.Struct.Mol.Biol., 18, 2011
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7VUX
| Complex structure of PD1 and 609A-Fab | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Huang, H, Zhu, Z, Zhao, J, Jiang, L, Yang, H, Deng, L, Meng, X, Ding, J, Yang, S, Zhao, L, Xu, W, Wang, X. | 登録日 | 2021-11-04 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | A strategy for the efficient construction of anti-PD1-based bispecific antibodies with desired IgG-like properties. Mabs, 14, 2022
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3H4R
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3VHZ
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3VI0
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7DDE
| Cryo-EM structure of the Ape4 and Nbr1 complex | 分子名称: | Aspartyl aminopeptidase 1,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | 著者 | Zhang, J, Ye, K. | 登録日 | 2020-10-28 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.26 Å) | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
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7DD9
| Cryo-EM structure of the Ams1 and Nbr1 complex | 分子名称: | Alpha-mannosidase,ZZ-type zinc finger-containing protein P35G2.11c,Maltose/maltodextrin-binding periplasmic protein, ZINC ION | 著者 | Zhang, J, Ye, K. | 登録日 | 2020-10-28 | 公開日 | 2021-07-14 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Molecular and structural mechanisms of ZZ domain-mediated cargo selection by Nbr1. Embo J., 40, 2021
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3SLP
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3SM4
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7X5V
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7UR5
| allo-tRNAUTu1 in the A, P, and E sites of the E. coli ribosome | 分子名称: | allo-tRNAUTu1 | 著者 | Zhang, J, Krahn, N, Prabhakar, A, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | 登録日 | 2022-04-21 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA. Nucleic Acids Res., 50, 2022
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7URI
| allo-tRNAUTu1A in the A site of the E. coli ribosome | 分子名称: | Allo-tRNAUTu1A | 著者 | Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | 登録日 | 2022-04-22 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA. Nucleic Acids Res., 50, 2022
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7URM
| allo-tRNAUTu1A in the P site of the E. coli ribosome | 分子名称: | allo-tRNAUTU1A | 著者 | Zhang, J, Prabhakar, A, Krahn, N, Vargas-Rodriguez, O, Krupkin, M, Fu, Z, Acosta-Reyes, F.J, Ge, X, Choi, J, Crnkovic, A, Ehrenberg, M, Viani Puglisi, E, Soll, D, Puglisi, J. | 登録日 | 2022-04-22 | 公開日 | 2022-08-10 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Uncovering translation roadblocks during the development of a synthetic tRNA. Nucleic Acids Res., 50, 2022
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7V3P
| Cryo-EM structure of the IGF1R/insulin complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | 著者 | Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C. | 登録日 | 2021-08-11 | 公開日 | 2022-08-17 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structure of the IGF1R/insulin complex To Be Published
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7CWE
| Human Fructose-1,6-bisphosphatase 1 in APO R-state | 分子名称: | Fructose-1,6-bisphosphatase 1, MAGNESIUM ION | 著者 | Chen, Y, Zhang, J, Li, C, Cao, Y. | 登録日 | 2020-08-28 | 公開日 | 2021-09-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Human Fructose-1,6-bisphosphatase 1 in APO R-state To Be Published
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7UPY
| An antibody from single human VH-rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | 登録日 | 2022-04-18 | 公開日 | 2022-08-10 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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7UPX
| Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, SP1-77 Fab heavy chain, SP1-77 Fab light chain, ... | 著者 | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | 登録日 | 2022-04-18 | 公開日 | 2022-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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7UPW
| Three RBD-down state of SARS-CoV-2 D614G spike in complex with the SP1-77 neutralizing antibody Fab fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, J, Luo, S, Kreutzberger, A, Kirchhausen, T, Chen, B, Haynes, B, Alt, F. | 登録日 | 2022-04-18 | 公開日 | 2022-08-10 | 最終更新日 | 2023-08-23 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | An antibody from single human V H -rearranging mouse neutralizes all SARS-CoV-2 variants through BA.5 by inhibiting membrane fusion. Sci Immunol, 7, 2022
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6IMH
| Solution Structure of Bicyclic Peptide pb-18 | 分子名称: | (ACE)-GLY-CYS-PRO-CYS-GLU-PRO-SER-TYR-LEU-CYS-PRO-TRP-LEU-PRO-GLY-CYS-(NH2) | 著者 | Yao, H, Lin, P, Zha, J, Zha, M, Zhao, Y, Wu, C. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 実験手法 | SOLUTION NMR | 主引用文献 | Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns. Chembiochem, 20, 2019
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6IMG
| Solution Structure of Bicyclic Peptide pb-13 | 分子名称: | (ACE)-GLY-CYS-PRO-CYS-ILE-TRP-PRO-GLU-LEU-CYS-PRO-TRP-ILE-ARG-SER-CYS-(NH2) | 著者 | Yao, H, Lin, P, Zha, J, Zha, M, Zhao, Y, Wu, C. | 登録日 | 2018-10-22 | 公開日 | 2019-08-28 | 実験手法 | SOLUTION NMR | 主引用文献 | Ordered and Isomerically Stable Bicyclic Peptide Scaffolds Constrained through Cystine Bridges and Proline Turns. Chembiochem, 20, 2019
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4X2A
| Crystal structure of mouse glyoxalase I complexed with baicalein | 分子名称: | 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Lactoylglutathione lyase, ZINC ION | 著者 | Zhang, H, Zhai, J, Zhang, L, Li, C, Zhao, Y, Hu, X. | 登録日 | 2014-11-26 | 公開日 | 2015-09-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis. Curr Top Med Chem, 16, 2016
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4URT
| The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R. | 登録日 | 2014-07-02 | 公開日 | 2014-09-10 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue Neuron, 83, 2014
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4GQG
| Crystal structure of AKR1B10 complexed with NADP+ | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhang, L, Zheng, X, Chen, S, Zhai, J, Hu, X. | 登録日 | 2012-08-23 | 公開日 | 2013-08-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111) Febs Lett., 587, 2013
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4I5X
| Crystal Structure Of AKR1B10 Complexed With NADP+ And Flufenamic acid | 分子名称: | 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhang, L, Zheng, X, Chen, S, Zhai, J, Zhang, H, Zhao, Y. | 登録日 | 2012-11-29 | 公開日 | 2013-10-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111) Febs Lett., 587, 2013
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