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5VE8
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BU of 5ve8 by Molmil
Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H3 1-28
分子名称: Histone H3, Kap123
著者An, S, Yoon, J, Song, J.-J, Cho, U.-S.
登録日2017-04-04
公開日2017-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
4QBR
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BU of 4qbr by Molmil
Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide
分子名称: DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION
著者Wang, H, Li, H.
登録日2014-05-08
公開日2015-05-13
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
To be Published
6TL8
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BU of 6tl8 by Molmil
Structural basis of SALM3 dimerization and adhesion complex formation with the presynaptic receptor protein tyrosine phosphatases
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Myeloid cell surface antigen CD33,Leucine-rich repeat and fibronectin type-III domain-containing protein 4
著者Karki, S, Shkumatov, A.V, Bae, S, Ko, J, Kajander, T.
登録日2019-12-02
公開日2020-07-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTP sigma.
Sci Rep, 10, 2020
6VAT
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BU of 6vat by Molmil
Structure of the periplasmic domain of YejM from Salmonella typhimurium
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, ETHANOLAMINE, ...
著者Gabale, U, Ressl, S.
登録日2019-12-17
公開日2020-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献The essential inner membrane protein YejM is a metalloenzyme.
Sci Rep, 10, 2020
6VC7
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BU of 6vc7 by Molmil
Structure of the F349A mutant of the periplasmic domain of YejM from Salmonella typhimurium
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ETHANOLAMINE, ...
著者Gabale, U, Ressl, S.
登録日2019-12-20
公開日2020-08-26
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The essential inner membrane protein YejM is a metalloenzyme.
Sci Rep, 10, 2020
6VDF
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BU of 6vdf by Molmil
Structure of the periplasmic domain of YejM from Salmonella typhimurium (twinned)
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ...
著者Gabale, U, Ressl, S.
登録日2019-12-25
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The essential inner membrane protein YejM is a metalloenzyme.
Sci Rep, 10, 2020
3H0T
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BU of 3h0t by Molmil
Hepcidin-Fab complex
分子名称: Fab fragment, Heavy chain, Light chain, ...
著者Syed, R, Li, V.
登録日2009-04-10
公開日2009-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Hepcidin revisited, disulfide connectivity, dynamics, and structure.
J.Biol.Chem., 284, 2009
2K21
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BU of 2k21 by Molmil
NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C
分子名称: Potassium voltage-gated channel subfamily E member
著者Kang, C, Tian, C, Sonnichsen, F.D, Smith, J.A, Meiler, J, George, A.L, Vanoye, C.G, Sanders, C.R, Kim, H.
登録日2008-03-19
公開日2008-12-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Biochemistry, 47, 2008
2KDC
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BU of 2kdc by Molmil
NMR Solution Structure of E. coli diacylglycerol kinase (DAGK) in DPC micelles
分子名称: Diacylglycerol kinase
著者Van Horn, W.D, Kim, H, Ellis, C.D, Hadziselimovic, A, Sulistijo, E.S, Karra, M.D, Tian, C, Sonnichsen, F.D, Sanders, C.R.
登録日2009-01-06
公開日2009-07-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase
Science, 324, 2009
2LYQ
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BU of 2lyq by Molmil
NOE-based 3D structure of the monomeric intermediate of CylR2 at 262K (-11 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYL
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BU of 2lyl by Molmil
NOE-based 3D structure of the predissociated homodimer of CylR2 in equilibrium with monomer at 266K (-7 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYS
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BU of 2lys by Molmil
NOE-based 3D structure of the monomeric partially-folded intermediate of CylR2 at 257K (-16 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYR
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BU of 2lyr by Molmil
NOE-based 3D structure of the monomeric partially-folded intermediate of CylR2 at 259K (-14 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYP
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BU of 2lyp by Molmil
NOE-based 3D structure of the monomer of CylR2 in equilibrium with predissociated homodimer at 266K (-7 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYJ
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BU of 2lyj by Molmil
NOE-based 3D structure of the CylR2 homodimer at 298K
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Giller, K, Becker, S, Zweckstetter, M, Schwieters, C.D.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
2LYK
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BU of 2lyk by Molmil
NOE-based 3D structure of the CylR2 homodimer at 270K (-3 Celsius degrees)
分子名称: CylR2
著者Jaremko, M, Jaremko, L, Kim, H, Cho, M, Schwieters, C.D, Giller, K, Becker, S, Zweckstetter, M.
登録日2012-09-19
公開日2013-02-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Cold denaturation of a protein dimer monitored at atomic resolution.
Nat.Chem.Biol., 9, 2013
6I60
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BU of 6i60 by Molmil
Structure of alpha-L-rhamnosidase from Dictyoglumus thermophilum
分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, Alpha-rhamnosidase, TRIETHYLENE GLYCOL
著者Lafite, P, Daniellou, R.
登録日2018-11-15
公開日2019-02-06
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.743 Å)
主引用文献Biochemical Characterization of the alpha-l-RhamnosidaseDtRha fromDictyoglomus thermophilum: Application to the Selective Derhamnosylation of Natural Flavonoids.
Acs Omega, 4, 2019
3SJF
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BU of 3sjf by Molmil
X-ray structure of human glutamate carboxypeptidase II in complex with a urea-based inhibitor (A25)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C.
登録日2011-06-21
公開日2011-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity.
J.Med.Chem., 54, 2011
3SJG
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BU of 3sjg by Molmil
Human glutamate carboxypeptidase II (E424A inactive mutant ) in complex with N-acetyl-aspartyl-aminooctanoic acid
分子名称: (2S)-2-[(N-acetyl-L-alpha-aspartyl)amino]nonanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C.
登録日2011-06-21
公開日2011-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity.
J.Med.Chem., 54, 2011
3SJE
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BU of 3sje by Molmil
X-ray structure of human glutamate carboxypeptidase II (the E424A inactive mutant) in complex with N-acetyl-aspartyl-aminononanoic acid
分子名称: (2S)-2-[(N-acetyl-L-alpha-aspartyl)amino]nonanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C.
登録日2011-06-21
公開日2011-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity.
J.Med.Chem., 54, 2011
3SJX
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BU of 3sjx by Molmil
X-ray structure of human glutamate carboxypeptidase II (the E424A inactive mutant) in complex with N-acetyl-aspartyl-methionine
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Plechanovova, A, Byun, Y, Alquicer, G, Skultetyova, L, Mlcochova, P, Nemcova, A, Kim, H, Navratil, M, Mease, R, Lubkowski, J, Pomper, M, Konvalinka, J, Rulisek, L, Barinka, C.
登録日2011-06-22
公開日2011-10-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity.
J.Med.Chem., 54, 2011
2IJN
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BU of 2ijn by Molmil
Isothiazoles as active-site inhibitors of HCV NS5B polymerase
分子名称: (2R,3R)-3-{[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO}-2-CYANO-3-THIOXOPROPANAMIDE, RNA polymerase NS5B
著者Yan, S, Yao, N.
登録日2006-09-29
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Isothiazoles as active-site inhibitors of HCV NS5B polymerase
Bioorg.Med.Chem.Lett., 17, 2007
5Z9G
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BU of 5z9g by Molmil
Crystal structure of KAI2
分子名称: Probable esterase KAI2
著者Kim, K.L, Cha, J.S, Soh, M.S, Cho, H.S.
登録日2018-02-03
公開日2018-08-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana.
J. Exp. Bot., 69, 2018
8JZM
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BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
登録日2023-07-05
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
7T63
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BU of 7t63 by Molmil
Crystal structure of a delta 6 18:0-ACP desaturase from Thunbergia laurifolia
分子名称: DESATURASE, FE (II) ION
著者Liu, Q, Chai, J, Shanklin, J.
登録日2021-12-13
公開日2022-07-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Divergent evolution of extreme production of variant plant monounsaturated fatty acids.
Proc.Natl.Acad.Sci.USA, 119, 2022

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