4QBR
Crystal structure of DNMT3a ADD domain G550D mutant bound to H3 peptide
Summary for 4QBR
Entry DOI | 10.2210/pdb4qbr/pdb |
Related | 4qbq 4qbs |
Descriptor | DNA (cytosine-5)-methyltransferase 3A, Histone H3, ZINC ION, ... (4 entities in total) |
Functional Keywords | zinc finger, histone binding, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9Y6K1 |
Total number of polymer chains | 4 |
Total formula weight | 33302.27 |
Authors | |
Primary citation | Noh, K.,Wang, H.,Kim, H.,Wenderski, W.,Fang, F.,Li, C.,Dewell, S.,Wu, X.,Ferris, A.,Hughes, S.H.,Zheng, D.,Melnick, A.M.,Patel, D.J.,Li, H.,Allis, C.D. Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs To be Published, |
Experimental method | X-RAY DIFFRACTION (1.902 Å) |
Structure validation
Download full validation report