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5VCH
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BU of 5vch by Molmil
Crystal structure of full-length Kluyveromyces lactis Kap123
分子名称: Kap123
著者An, S, Yoon, J, Song, J.-J, Cho, U.-S.
登録日2017-03-31
公開日2017-11-01
最終更新日2022-03-16
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
5VKT
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BU of 5vkt by Molmil
Cinnamyl alcohol dehydrogenases (SbCAD4) from Sorghum bicolor (L.) Moench
分子名称: ACETATE ION, Cinnamyl alcohol dehydrogenases (SbCAD4), D-MALATE, ...
著者Walker, A.M, Jun, S.Y, Kang, C.
登録日2017-04-22
公開日2017-08-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.827 Å)
主引用文献The Enzyme Activity and Substrate Specificity of Two Major Cinnamyl Alcohol Dehydrogenases in Sorghum (Sorghum bicolor), SbCAD2 and SbCAD4.
Plant Physiol., 174, 2017
5VE8
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BU of 5ve8 by Molmil
Crystal structure of full-length Kluyveromyces lactis Kap123 with histone H3 1-28
分子名称: Histone H3, Kap123
著者An, S, Yoon, J, Song, J.-J, Cho, U.-S.
登録日2017-04-04
公開日2017-11-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure-based nuclear import mechanism of histones H3 and H4 mediated by Kap123.
Elife, 6, 2017
7KNW
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BU of 7knw by Molmil
Crystal structure of SND1 in complex with C-26-A2
分子名称: 5-chloro-2-methoxy-N-([1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide, GLYCEROL, Staphylococcal nuclease domain-containing protein 1
著者Kang, Y.
登録日2020-11-06
公開日2021-12-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Nat Cancer, 3, 2022
7KNX
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BU of 7knx by Molmil
Crystal structure of SND1 in complex with C-26-A6
分子名称: 5-chloro-2-methoxy-N-(2-methyl[1,2,4]triazolo[1,5-a]pyridin-8-yl)benzene-1-sulfonamide, GLYCEROL, Staphylococcal nuclease domain-containing protein 1, ...
著者Kang, Y.
登録日2020-11-06
公開日2021-12-08
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Nat Cancer, 3, 2022
6LBX
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BU of 6lbx by Molmil
Crystal structure of HER2 Domain IV and Rb-H2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor tyrosine-protein kinase erbB-2, Repebody (Rb-H2)
著者Cho, H.S, Cha, J.S.
登録日2019-11-15
公開日2020-11-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2
Comput Struct Biotechnol J, 19, 2021
1LCP
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BU of 1lcp by Molmil
BOVINE LENS LEUCINE AMINOPEPTIDASE COMPLEXED WITH L-LEUCINE PHOSPHONIC ACID
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, LEUCINE AMINOPEPTIDASE, LEUCINE PHOSPHONIC ACID, ...
著者Straeter, N, Lipscomb, W.N.
登録日1995-05-12
公開日1995-07-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Transition state analogue L-leucinephosphonic acid bound to bovine lens leucine aminopeptidase: X-ray structure at 1.65 A resolution in a new crystal form.
Biochemistry, 34, 1995
4EN1
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BU of 4en1 by Molmil
The 1.62A structure of a FRET-optimized Cerulean Fluorescent Protein
分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Watkins, J.L.
登録日2012-04-12
公開日2013-04-24
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The 1.6 A resolution structure of a FRET-optimized Cerulean fluorescent protein.
Acta Crystallogr.,Sect.D, 69, 2013
4FJO
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BU of 4fjo by Molmil
Structure of the Rev1 CTD-Rev3/7-Pol kappa RIR complex
分子名称: DNA polymerase kappa, DNA polymerase zeta catalytic subunit, DNA repair protein REV1, ...
著者Wojtaszek, J, Lee, C.-J, Zhou, P.
登録日2012-06-11
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.718 Å)
主引用文献Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric Pol zeta and Pol kappa
J.Biol.Chem., 287, 2012
5XB1
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BU of 5xb1 by Molmil
human ferritin mutant - E-helix deletion
分子名称: Ferritin heavy chain
著者Lee, S.G, Ahn, B.J, Jeong, H, Kim, H, Hyun, J, Jung, Y.
登録日2017-03-15
公開日2018-02-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release
Angew. Chem. Int. Ed. Engl., 57, 2018
2IJN
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BU of 2ijn by Molmil
Isothiazoles as active-site inhibitors of HCV NS5B polymerase
分子名称: (2R,3R)-3-{[3,5-BIS(TRIFLUOROMETHYL)PHENYL]AMINO}-2-CYANO-3-THIOXOPROPANAMIDE, RNA polymerase NS5B
著者Yan, S, Yao, N.
登録日2006-09-29
公開日2006-11-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Isothiazoles as active-site inhibitors of HCV NS5B polymerase
Bioorg.Med.Chem.Lett., 17, 2007
6LHU
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BU of 6lhu by Molmil
High resolution structure of FANCA C-terminal domain (CTD)
分子名称: Fanconi anemia complementation group A
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
6LHW
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BU of 6lhw by Molmil
Structure of N-terminal and C-terminal domains of FANCA
分子名称: Fanconi anemia complementation group A
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.84 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
5YI5
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BU of 5yi5 by Molmil
human ferritin mutant - E-helix deletion
分子名称: Ferritin heavy chain
著者Lee, S.G, Yoon, H.R, Ahn, B.J, Jeong, H, Hyun, J, Jung, Y, Kim, H.
登録日2017-10-02
公開日2018-02-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Four-fold Channel-Nicked Human Ferritin Nanocages for Active Drug Loading and pH-Responsive Drug Release
Angew. Chem. Int. Ed. Engl., 57, 2018
6LHS
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BU of 6lhs by Molmil
High resolution structure of FANCA C-terminal domain (CTD)
分子名称: Fanconi anemia complementation group A
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
6LHV
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BU of 6lhv by Molmil
Structure of FANCA and FANCG Complex
分子名称: Fanconi anemia complementation group A, Fanconi anemia complementation group G
著者Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y.
登録日2019-12-10
公開日2020-03-25
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.59 Å)
主引用文献Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex.
Nucleic Acids Res., 48, 2020
4O6G
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BU of 4o6g by Molmil
Rv3902c from M. tuberculosis
分子名称: Uncharacterized protein
著者Reddy, B.G, Moates, D.B, Kim, H, Green, T.J, Kim, C, Terwilliger, T.J, Delucas, L.J, TB Structural Genomics Consortium (TBSGC)
登録日2013-12-20
公開日2014-03-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献1.55 angstrom resolution X-ray crystal structure of Rv3902c from Mycobacterium tuberculosis.
Acta Crystallogr F Struct Biol Commun, 70, 2014
4WXR
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BU of 4wxr by Molmil
X-ray crystal structure of NS3 Helicase from HCV with a bound inhibitor at 2.42 A resolution
分子名称: NS3, {6-(3,5-diaminophenyl)-1-[4-(propan-2-yl)benzyl]-1H-indol-3-yl}acetic acid
著者Davies, D.R, Kim, H, Lorimer, D.
登録日2014-11-14
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献crystal structure of NS3 Helicase from HCV with a bound inhibitor
TO BE PUBLISHED
2LM4
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BU of 2lm4 by Molmil
Solution NMR Structure of mitochondrial succinate dehydrogenase assembly factor 2 from Saccharomyces cerevisiae, Northeast Structural Genomics Consortium Target YT682A
分子名称: Succinate dehydrogenase assembly factor 2, mitochondrial
著者Eletsky, A, Winge, D.R, Lee, H, Lee, D, Kohan, E, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP)
登録日2011-11-22
公開日2012-01-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR structure of yeast succinate dehydrogenase flavinylation factor sdh5 reveals a putative sdh1 binding site.
Biochemistry, 51, 2012
7CM0
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BU of 7cm0 by Molmil
Crystal structure of a glutaminyl cyclase in complex with NHV-1009
分子名称: 1-(cyclopentylmethyl)-1-[3-methoxy-4-(2-morpholin-4-ylethoxy)phenyl]-3-[3-(5-methylimidazol-1-yl)propyl]urea, Glutaminyl-peptide cyclotransferase, ZINC ION
著者Lee, J.W, Song, J.Y, Jang, T.H, Ha, J.H.
登録日2020-07-23
公開日2021-12-22
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design.
Eur.J.Med.Chem., 226, 2021
6JQ7
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BU of 6jq7 by Molmil
The ligand-free structure of human PPARgamma LBD in the presence of the SRC-1 coactivator peptide
分子名称: 16-mer peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者Jang, J.Y, Han, B.W.
登録日2019-03-29
公開日2019-10-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for the inhibitory effects of a novel reversible covalent ligand on PPAR gamma phosphorylation.
Sci Rep, 9, 2019
2Q8A
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BU of 2q8a by Molmil
Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody
分子名称: 1F9 heavy chain, 1F9 light chain, Apical membrane antigen 1
著者Gupta, A, Murphy, V.J, Anders, R.F, Batchelor, A.H.
登録日2007-06-10
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
PLoS Pathog., 3, 2007
2Q8B
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BU of 2q8b by Molmil
Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody
分子名称: 1F9 heavy chain, 1F9 light chain, Apical membrane antigen 1
著者Gupta, A, Murphy, V.J, Anders, R.F, Batchelor, A.H.
登録日2007-06-10
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
Plos Pathog., 3, 2007
3GP3
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BU of 3gp3 by Molmil
Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with 2-phosphoserine
分子名称: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, PHOSPHITE ION, PHOSPHOSERINE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2009-03-20
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase.
Acta Crystallogr.,Sect.F, 67, 2011
2K21
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BU of 2k21 by Molmil
NMR structure of human KCNE1 in LMPG micelles at pH 6.0 and 40 degree C
分子名称: Potassium voltage-gated channel subfamily E member
著者Kang, C, Tian, C, Sonnichsen, F.D, Smith, J.A, Meiler, J, George, A.L, Vanoye, C.G, Sanders, C.R, Kim, H.
登録日2008-03-19
公開日2008-12-09
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.
Biochemistry, 47, 2008

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