6LBX

Crystal structure of HER2 Domain IV and Rb-H2

Summary for 6LBX

Entry DOI	10.2210/pdb6lbx/pdb
Descriptor	Repebody (Rb-H2), Receptor tyrosine-protein kinase erbB-2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	kinase, protein binding
Biological source	Cyclostomata More
Total number of polymer chains	2
Total formula weight	41779.75
Authors	Cho, H.S.,Cha, J.S. (deposition date: 2019-11-15, release date: 2020-11-18, Last modification date: 2024-10-23)
Primary citation	Kim, T.Y.,Cha, J.S.,Kim, H.,Choi, Y.,Cho, H.S.,Kim, H.S. Computationally-guided design and affinity improvement of a protein binder targeting a specific site on HER2 Comput Struct Biotechnol J, 19:1325-1334, 2021 Cited by DOI: 10.1016/j.csbj.2021.02.013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation