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2VB5
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BU of 2vb5 by Molmil
Solution structure of W60G mutant of human beta2-microglobulin
Descriptor: BETA-2-MICROGLOBULIN
Authors:Esposito, G, Corazza, A, Rennella, E, Gumral, D, Mimmi, M.C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M, Bellotti, V.
Deposit date:2007-09-06
Release date:2007-09-25
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The Controlling Roles of Trp60 and Trp95 in Beta2-Microglobulin Function, Folding and Amyloid Aggregation Properties.
J.Mol.Biol., 378, 2008
1FTT
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BU of 1ftt by Molmil
THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN (RATTUS NORVEGICUS)
Descriptor: THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN
Authors:Fogolari, F, Esposito, G, Damante, G, Formisano, S, Di Lauro, R, Viglino, P.
Deposit date:1995-10-03
Release date:1996-01-29
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics.
Eur.J.Biochem., 241, 1996
1JNJ
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BU of 1jnj by Molmil
NMR solution structure of the human beta2-microglobulin
Descriptor: beta2-microglobulin
Authors:Verdone, G, Corazza, A, Viglino, P, Pettirossi, F, Giorgetti, S, Mangione, P, Andreola, A, Stoppini, M, Bellotti, V, Esposito, G.
Deposit date:2001-07-24
Release date:2002-02-27
Last modified:2022-02-23
Method:SOLUTION NMR
Cite:The solution structure of human beta2-microglobulin reveals the prodromes of its amyloid transition.
Protein Sci., 11, 2002
1Y9O
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BU of 1y9o by Molmil
1H NMR Structure of Acylphosphatase from the hyperthermophile Sulfolobus Solfataricus
Descriptor: Acylphosphatase
Authors:Corazza, A, Rosano, C, Pagano, K, Alverdi, V, Esposito, G, Capanni, C, Bemporad, F, Plakoutsi, G, Stefani, M, Chiti, F, Zuccotti, S, Bolognesi, M, Viglino, P.
Deposit date:2004-12-16
Release date:2005-11-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure, conformational stability, and enzymatic properties of acylphosphatase from the hyperthermophile Sulfolobus solfataricus
Proteins, 62, 2006
7EH3
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BU of 7eh3 by Molmil
Structure of Nanobody Nb23 in solution using NMR spectroscopy
Descriptor: Nb23
Authors:Percipalle, M, Hunashal, Y, Esposito, G, Fogolari, F.
Deposit date:2021-03-28
Release date:2021-07-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of Nanobody Nb23.
Molecules, 26, 2021
2KA3
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BU of 2ka3 by Molmil
Structure of EMILIN-1 C1Q-like domain
Descriptor: EMILIN-1
Authors:Verdone, G, Corazza, A, Colebrooke, S.A, Cicero, D.O, Eliseo, T, Boyd, J, Doliana, R, Fogolari, F, Viglino, P, Colombatti, A, Campbell, I.D, Esposito, G.
Deposit date:2008-10-30
Release date:2008-11-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR-based homology model for the solution structure of the C-terminal globular domain of EMILIN1
J.Biomol.Nmr, 43, 2009
2OII
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BU of 2oii by Molmil
Structure of EMILIN-1 C1q-like domain
Descriptor: EMILIN-1
Authors:Verdone, G, Colebrooke, S.A, Corazza, A, Cicero, D.O, Eliseo, T, Viglino, P, Campbell, I.D, Colombatti, A, Esposito, G.
Deposit date:2007-01-11
Release date:2008-01-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The solution structure of the C-terminal domain of EMILIN-1
To be Published
2GV1
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BU of 2gv1 by Molmil
NMR solution structure of the Acylphosphatase from Eschaerichia Coli
Descriptor: Probable acylphosphatase
Authors:Pagano, K, Corazza, A, Viglino, P, Esposito, G.
Deposit date:2006-05-02
Release date:2006-10-31
Last modified:2024-10-16
Method:SOLUTION NMR
Cite:NMR solution structure of the acylphosphatase from Escherichia coli.
J.Biomol.Nmr, 36, 2006
1PY4
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BU of 1py4 by Molmil
Beta2 microglobulin mutant H31Y displays hints for amyloid formations
Descriptor: Beta-2-microglobulin precursor
Authors:Rosano, C, Zuccotti, S, Mangione, P, Giorgetti, S, Bellotti, V, Pettirossi, F, Corazza, A, Viglino, P, Esposito, G, Bolognesi, M.
Deposit date:2003-07-08
Release date:2004-05-04
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:beta2-microglobulin H31Y variant 3D structure highlights the protein natural propensity towards intermolecular aggregation
J.Mol.Biol., 335, 2004
2K27
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BU of 2k27 by Molmil
Solution structure of Human Pax8 Paired Box Domain
Descriptor: Paired box protein Pax-8
Authors:Codutti, L, Esposito, G, Corazza, A, Fogolari, F, Tell, G, Vascotto, C, van Ingen, H, Boelens, R, Viglino, P, Quadrifoglio, F.
Deposit date:2008-03-26
Release date:2008-09-30
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:The Solution Structure of DNA-free Pax-8 Paired Box Domain Accounts for Redox Regulation of Transcriptional Activity in the Pax Protein Family.
J.Biol.Chem., 283, 2008
2Z9T
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BU of 2z9t by Molmil
Crystal structure of the human beta-2 microglobulin mutant W60G
Descriptor: Beta-2-microglobulin
Authors:Ricagno, S, Bolognesi, M, Bellotti, V, Corazza, A, Rennella, E, Gural, D, Mimmi, M.C, Betto, E, Pucillo, C, Fogolari, F, Viglino, P, Raimondi, S, Giorgetti, S, Bolognesi, B, Merlini, G, Stoppini, M.
Deposit date:2007-09-26
Release date:2008-04-22
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The controlling roles of Trp60 and Trp95 in beta2-microglobulin function, folding and amyloid aggregation properties
J.Mol.Biol., 378, 2008
4N1H
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BU of 4n1h by Molmil
Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-10-04
Release date:2014-10-08
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
3MKP
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BU of 3mkp by Molmil
Crystal structure of 1K1 mutant of Hepatocyte Growth Factor/Scatter Factor fragment NK1 in complex with heparin
Descriptor: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Gherardi, E, Chirgadze, D.Y, Blundell, T.L.
Deposit date:2010-04-15
Release date:2010-08-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Engineering a fragment of Hepatocyte Growth Factor/Scatter Factor for tissue and organ regeneration
To be Published
3QDA
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BU of 3qda by Molmil
Crystal structure of W95L beta-2 microglobulin
Descriptor: Beta-2-microglobulin, TRIETHYLENE GLYCOL
Authors:Ricagno, S, Bellotti, V, Bolognesi, M.
Deposit date:2011-01-18
Release date:2011-06-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:The two tryptophans of beta2-microglobulin have distinct roles in function and folding and might represent two independent responses to evolutionary pressure.
BMC Evol Biol, 11, 2011
2BJE
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BU of 2bje by Molmil
Acylphosphatase from Sulfolobus solfataricus. Monclinic P21 space group
Descriptor: ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION
Authors:Rosano, C, Zuccotti, S.
Deposit date:2005-02-02
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
2BJD
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BU of 2bjd by Molmil
Sulfolobus Solfataricus Acylphosphatase. Triclinic space group
Descriptor: ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ...
Authors:Rosano, C, Zuccotti, S, Bolognesi, M.
Deposit date:2005-02-02
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
5CKA
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BU of 5cka by Molmil
Human beta-2 microglobulin double mutant W60G-N83V
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKG
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BU of 5ckg by Molmil
Human beta-2 microglobulin mutant V85E
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
4L3C
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BU of 4l3c by Molmil
Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-05
Release date:2013-12-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4L29
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BU of 4l29 by Molmil
Structure of wtMHC class I with NY-ESO1 double mutant
Descriptor: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
Authors:Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S.
Deposit date:2013-06-04
Release date:2013-12-25
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin.
J.Biol.Chem., 289, 2014
4M3K
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BU of 4m3k by Molmil
Structure of a single domain camelid antibody fragment cAb-H7S in complex with the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Beta-lactamase, CHLORIDE ION, Camelid heavy-chain antibody variable fragment cAb-H7S
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
4M3J
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BU of 4m3j by Molmil
Structure of a single-domain camelid antibody fragment cAb-H7S specific of the BlaP beta-lactamase from Bacillus licheniformis
Descriptor: Camelid heavy-chain antibody variable fragment cAb-H7S, SULFATE ION
Authors:Pain, C, Kerff, F, Herman, R, Sauvage, E, Preumont, S, Charlier, P, Dumoulin, M.
Deposit date:2013-08-06
Release date:2014-08-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published
7RKT
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BU of 7rkt by Molmil
Naegleria fowleri CYP51 (NfCYP51) complex with (S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate
Descriptor: (1S)-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl 3-(trifluoromethyl)benzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Sharma, V, Podust, L.M.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors.
J.Med.Chem., 2023
7RKW
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Naegleria fowleri CYP51(NfCYP51) complex with (S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate
Descriptor: (1S)-1-(4-fluorophenyl)-2-(1H-imidazol-1-yl)ethyl 3,5-dichlorobenzoate, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Sharma, V, Podust, L.M.
Deposit date:2021-07-22
Release date:2022-07-27
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Miconazole-like Scaffold is a Promising Lead for Naegleria fowleri -Specific CYP51 Inhibitors.
J.Med.Chem., 2023

 

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