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4N1H

Structure of a single-domain camelid antibody fragment cAb-F11N in complex with the BlaP beta-lactamase from Bacillus licheniformis

Summary for 4N1H
Entry DOI10.2210/pdb4n1h/pdb
Related4M3J 4M3K
DescriptorBeta-lactamase, Camelid heavy-chain antibody variable fragment cAb-F11N (3 entities in total)
Functional Keywordsimmunoglobulin fold, antigen binding, hydrolase-immune system complex, hydrolase/immune system
Biological sourceBacillus licheniformis
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Cellular locationCell membrane; Lipid-anchor (Probable): P00808
Total number of polymer chains4
Total formula weight90042.72
Authors
Pain, C.,Kerff, F.,Herman, R.,Sauvage, E.,Preumont, S.,Charlier, P.,Dumoulin, M. (deposition date: 2013-10-04, release date: 2014-10-08, Last modification date: 2023-09-20)
Primary citationPain, C.,Cosolo, A.,Preumont, S.,Scarafone, N.,Thorn, D.,Herman, R.,Spiegel, H.,Pardon, E.,Matagne, A.,Charlier, P.,Steyaert, J.,Damblon, C.,Kerff, F.,Esposito, G.,Dumoulin, M.
Probing the mechanism of aggregation of polyQ model proteins with camelid heavy-chain antibody fragments
To be Published,
Experimental method
X-RAY DIFFRACTION (3 Å)
Structure validation

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