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5Y0Y
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BU of 5y0y by Molmil
RVFV GN-AU
Descriptor: GOLD ION, NSmGnGc
Authors:Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
Deposit date:2017-07-19
Release date:2017-09-13
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.398 Å)
Cite:Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5Y11
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BU of 5y11 by Molmil
SFTSV GN with neutralizing antibody MAb4-5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAb 4-5 heavy chain, MAb 4-5 light chain, ...
Authors:Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
Deposit date:2017-07-19
Release date:2017-09-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4Z55
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BU of 4z55 by Molmil
Anaplastic lymphoma kinase catalytic domain complexed with pyrazolopyrimidine derivative of LDK378
Descriptor: ALK tyrosine kinase receptor, GLYCEROL, N~6~-[5-methyl-4-(1-methylpiperidin-4-yl)-2-(propan-2-yloxy)phenyl]-N~4~-[2-(propan-2-ylsulfonyl)phenyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6-diamine
Authors:Lee, C.C, Spraggon, G.
Deposit date:2015-04-02
Release date:2016-02-03
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
5Y0W
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BU of 5y0w by Molmil
The structure of RVFV Gn head domain
Descriptor: NSmGnGc
Authors:Wu, Y, Gao, F, Qi, J.X, Chai, Y, Gao, G.F.
Deposit date:2017-07-19
Release date:2017-09-13
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of phlebovirus glycoprotein Gn and identification of a neutralizing antibody epitope
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7VHQ
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BU of 7vhq by Molmil
Structural insights into the membrane microdomain organization by SPFH family proteins
Descriptor: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK
Authors:Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N.
Deposit date:2021-09-22
Release date:2022-01-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
1G66
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BU of 1g66 by Molmil
ACETYLXYLAN ESTERASE AT 0.90 ANGSTROM RESOLUTION
Descriptor: ACETYL XYLAN ESTERASE II, GLYCEROL, SULFATE ION
Authors:Ghosh, D, Sawicki, M, Lala, P, Erman, M, Pangborn, W, Eyzaguirre, J, Gutierrez, R, Jornvall, H, Thiel, D.J.
Deposit date:2000-11-03
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Multiple conformations of catalytic serine and histidine in acetylxylan esterase at 0.90 A.
J.Biol.Chem., 276, 2001
7VHP
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BU of 7vhp by Molmil
Structural insights into the membrane microdomain organization by SPFH family proteins
Descriptor: ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK
Authors:Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N.
Deposit date:2021-09-22
Release date:2022-03-23
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
7Y5Q
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BU of 7y5q by Molmil
Structure of 1:1 PAPP-A.STC2 complex(half map)
Descriptor: Maltose/maltodextrin-binding periplasmic protein,Pappalysin-1, Stanniocalcin-2, ZINC ION
Authors:Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
Deposit date:2022-06-17
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
7Y5N
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BU of 7y5n by Molmil
Structure of 1:1 PAPP-A.ProMBP complex(half map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bone marrow proteoglycan, ...
Authors:Zhong, Q.H, Chu, H.L, Wang, G.P, Zhang, C, Wei, Y, Qiao, J, Hang, J.
Deposit date:2022-06-17
Release date:2023-01-11
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.
Cell Discov, 8, 2022
4GX8
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BU of 4gx8 by Molmil
Crystal structure of a DNA polymerase III alpha-epsilon chimera
Descriptor: CHLORIDE ION, DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha
Authors:Robinson, A, Horan, N, Xu, Z.-Q, Dixon, N.E, Oakley, A.J.
Deposit date:2012-09-04
Release date:2013-04-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain
Nucleic Acids Res., 41, 2013
6M4J
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BU of 6m4j by Molmil
SspA in complex with cysteine
Descriptor: CYSTEINE, PYRIDOXAL-5'-PHOSPHATE, SspA complex protein
Authors:Liu, L, Gao, H.
Deposit date:2020-03-07
Release date:2020-04-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System.
Mbio, 11, 2020
6IUF
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BU of 6iuf by Molmil
Crystal structure of Anti-CRISPR protein AcrVA5
Descriptor: ACETYL COENZYME *A, GLYCEROL, protein-a
Authors:Dong, L, Guan, X, Zhu, Y, Huang, Z.
Deposit date:2018-11-28
Release date:2019-04-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:An anti-CRISPR protein disables type V Cas12a by acetylation.
Nat. Struct. Mol. Biol., 26, 2019
5E08
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BU of 5e08 by Molmil
Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment
Descriptor: Fab Heavy Chain, Fab Light Chain, RNA
Authors:Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A.
Deposit date:2015-09-28
Release date:2016-09-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
5H65
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BU of 5h65 by Molmil
Crystal structure of human POT1 and TPP1
Descriptor: Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION
Authors:Chen, C, Wu, J, Lei, M.
Deposit date:2016-11-10
Release date:2017-05-31
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer.
Nat Commun, 8, 2017
1S5I
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BU of 1s5i by Molmil
Fab (LNKB-2) of monoclonal antibody to Human Interleukin-2, crystal structure
Descriptor: Fab-fragment of monoclonal antibody
Authors:Pletnev, V.Z, Goryacheva, E.A, Tsygannik, I.N, Nesmeyanov, V.A, Pletnev, S.V, Pangborn, W, Duax, W.
Deposit date:2004-01-21
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:[A new crystal form of the Fab fragment of a monoclonal antibody to human interleukin-2: the three-dimensional structure at 2.7 A resolution].
Bioorg. Khim., 30
7CE2
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BU of 7ce2 by Molmil
The Crystal structure of TeNT Hc complexed with neutralizing antibody
Descriptor: Tetanus toxin, neutralizing antibody heavy chain, neutralizing antibody light chain
Authors:Wang, X, Wang, Y, Wu, C, Yu, J, Liao, H.
Deposit date:2020-06-21
Release date:2021-04-07
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural basis of tetanus toxin neutralization by native human monoclonal antibodies.
Cell Rep, 35, 2021
8HXQ
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BU of 8hxq by Molmil
Nanobody1 in complex with human BCMA ECD
Descriptor: Nanobody1, Tumor necrosis factor receptor superfamily member 17
Authors:Sun, Y, Zhang, B.
Deposit date:2023-01-05
Release date:2024-01-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity.
Signal Transduct Target Ther, 8, 2023
8HXR
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BU of 8hxr by Molmil
Nanobody2 in complex with human BCMA ECD
Descriptor: Nanobody2, Tumor necrosis factor receptor superfamily member 17
Authors:Sun, Y, Zhang, B.
Deposit date:2023-01-05
Release date:2024-01-03
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity.
Signal Transduct Target Ther, 8, 2023
8HGO
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BU of 8hgo by Molmil
The EGF-bound EGFR/HER2 ectodomain complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor, ...
Authors:Zhang, Z, Bai, X.
Deposit date:2022-11-15
Release date:2023-02-08
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
8HGP
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BU of 8hgp by Molmil
The EREG-bound EGFR/HER2 ectodomain complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Zhang, Z, Bai, X.
Deposit date:2022-11-15
Release date:2023-02-08
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (4.53 Å)
Cite:Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
8HGS
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BU of 8hgs by Molmil
The EGF-bound EGFR ectodomain homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Pro-epidermal growth factor, ...
Authors:Zhang, Z, Bai, X.
Deposit date:2022-11-15
Release date:2023-02-15
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Structure and dynamics of the EGFR/HER2 heterodimer.
Cell Discov, 9, 2023
7JRA
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BU of 7jra by Molmil
HUMAN TNF-ALPHA IN COMPLEX WITH 2-[5-(3-chloro-4-{[(1R)-1-(2-fluorophenyl)ethyl]amino}quinolin-6-yl)pyrimidin-2-yl]propan-2-ol
Descriptor: 2-[5-(3-chloro-4-{[(1R)-1-(2-fluorophenyl)ethyl]amino}quinolin-6-yl)pyrimidin-2-yl]propan-2-ol, GLYCEROL, Tumor necrosis factor
Authors:Sheriff, S.
Deposit date:2020-08-11
Release date:2020-12-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNF alpha Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches.
J.Med.Chem., 63, 2020
3W1E
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BU of 3w1e by Molmil
Structure of FlgT, a flagellar basal body component protein
Descriptor: Flagella basal-body protein
Authors:Terashima, H, Sakuma, M, Homma, M, Imada, K.
Deposit date:2012-11-14
Release date:2013-04-03
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insight into the assembly mechanism in the supramolecular rings of the sodium-driven Vibrio flagellar motor from the structure of FlgT
Proc.Natl.Acad.Sci.USA, 110, 2013
3WPX
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BU of 3wpx by Molmil
Structure of PomBc4, a periplasmic fragment of PomB from Vibrio alginolyticus
Descriptor: PomB
Authors:Takao, M, Sakuma, M, Zhu, S, Homma, M, Kojima, S, Imada, K.
Deposit date:2014-01-17
Release date:2014-09-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational change in the periplasmic region of the flagellar stator coupled with the assembly around the rotor
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
5WFY
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BU of 5wfy by Molmil
Crystal structure of DNA-binding domain of the bacteriophage T4 ligase
Descriptor: DNA ligase, GLYCEROL
Authors:Shi, K, Aihara, H.
Deposit date:2017-07-13
Release date:2018-09-26
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Nucleic Acids Res., 46, 2018

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