7Y5N

Structure of 1:1 PAPP-A.ProMBP complex(half map)

Summary for 7Y5N

• Entry DOI: 10.2210/pdb7y5n/pdb
• EMDB information: 33621
• Descriptor: Bone marrow proteoglycan, Pappalysin-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase, metal binding protein-hydrolase complex, metal binding protein/hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 373169.97

Authors

Zhong, Q.H.,Chu, H.L.,Wang, G.P.,Zhang, C.,Wei, Y.,Qiao, J.,Hang, J. (deposition date: 2022-06-17, release date: 2023-01-11)

• Primary citation: Zhong, Q.,Chu, H.,Wang, G.,Zhang, C.,Li, R.,Guo, F.,Meng, X.,Lei, X.,Zhou, Y.,Ren, R.,Tao, L.,Li, N.,Gao, N.,Wei, Y.,Qiao, J.,Hang, J.; Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.; Cell Discov, 8:137-137, 2022; PubMed: 36550107; DOI: 10.1038/s41421-022-00502-2

Experimental method

ELECTRON MICROSCOPY (3.45 Å)