2GS7
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![BU of 2gs7 by Molmil](/molmil-images/mine/2gs7) | Crystal Structure of the inactive EGFR kinase domain in complex with AMP-PNP | Descriptor: | Epidermal growth factor receptor, IODIDE ION, MAGNESIUM ION, ... | Authors: | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | Deposit date: | 2006-04-25 | Release date: | 2006-06-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor Cell(Cambridge,Mass.), 125, 2006
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1TXK
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![BU of 1txk by Molmil](/molmil-images/mine/1txk) | Crystal structure of Escherichia coli OpgG | Descriptor: | Glucans biosynthesis protein G, SODIUM ION | Authors: | Hanoulle, X, Rollet, E, Clantin, B, Landrieu, I, Odberg-Ferragut, C, Lippens, G, Bohin, J.P, Villeret, V. | Deposit date: | 2004-07-05 | Release date: | 2004-09-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Analysis of Escherichia coli OpgG, a Protein Required for the Biosynthesis of Osmoregulated Periplasmic Glucans. J.Mol.Biol., 342, 2004
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1AI0
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![BU of 1ai0 by Molmil](/molmil-images/mine/1ai0) | R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | Deposit date: | 1997-04-30 | Release date: | 1997-11-12 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structures of the R6 human insulin hexamer. Biochemistry, 36, 1997
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5Z94
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![BU of 5z94 by Molmil](/molmil-images/mine/5z94) | |
5ZE3
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![BU of 5ze3 by Molmil](/molmil-images/mine/5ze3) | |
1AIY
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![BU of 1aiy by Molmil](/molmil-images/mine/1aiy) | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES | Descriptor: | PHENOL, R6 INSULIN HEXAMER, ZINC ION | Authors: | Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J. | Deposit date: | 1997-04-30 | Release date: | 1997-11-12 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structures of the R6 human insulin hexamer. Biochemistry, 36, 1997
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6J6A
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![BU of 6j6a by Molmil](/molmil-images/mine/6j6a) | |
5ZH9
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![BU of 5zh9 by Molmil](/molmil-images/mine/5zh9) | |
2MX6
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![BU of 2mx6 by Molmil](/molmil-images/mine/2mx6) | |
8T3Q
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![BU of 8t3q by Molmil](/molmil-images/mine/8t3q) | Cryo-EM structure of the DHA bound FFA4-Gq complex | Descriptor: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, Free fatty acid receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | Deposit date: | 2023-06-07 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10, 2024
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8T3O
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![BU of 8t3o by Molmil](/molmil-images/mine/8t3o) | Cryo-EM structure of the TUG-891 bound FFA4-Gq complex | Descriptor: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, ... | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | Deposit date: | 2023-06-07 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10, 2024
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8T3S
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![BU of 8t3s by Molmil](/molmil-images/mine/8t3s) | Cryo-EM structure of the Butyrate bound FFA2-Gq complex | Descriptor: | CHOLESTEROL, Free fatty acid receptor 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, Tikhonova, I, Milligan, G, Zhang, C. | Deposit date: | 2023-06-07 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Structural basis for the ligand recognition and signaling of free fatty acid receptors. Sci Adv, 10, 2024
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6K5L
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![BU of 6k5l by Molmil](/molmil-images/mine/6k5l) | The crystal structure of isocitrate dehydrogenase kinase/phosphatase wtih two Mn2+ from E. coli | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase kinase/phosphatase, ... | Authors: | Zhang, X, Lei, Z, Zheng, J, Jia, Z. | Deposit date: | 2019-05-29 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Characterization of metal binding of bifunctional kinase/phosphatase AceK and implication in activity modulation. Sci Rep, 9, 2019
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8JSD
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![BU of 8jsd by Molmil](/molmil-images/mine/8jsd) | Alginate lyase mutant-D180G | Descriptor: | Alginate lyase | Authors: | Zhang, X, Pan, L.X, Yang, D.F. | Deposit date: | 2023-06-19 | Release date: | 2024-06-26 | Method: | X-RAY DIFFRACTION (1.414 Å) | Cite: | Substrate-binding mode guided protein design of alginate lyase FlAlyA for altered end-product distribution To Be Published
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8JT4
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6LSV
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![BU of 6lsv by Molmil](/molmil-images/mine/6lsv) | Crystal structure of JOX2 in complex with 2OG, Fe, and JA | Descriptor: | 2-OXOGLUTARIC ACID, FE (III) ION, Probable 2-oxoglutarate-dependent dioxygenase At5g05600, ... | Authors: | Zhang, X, Wang, D, Liu, J. | Deposit date: | 2020-01-20 | Release date: | 2021-02-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.651 Å) | Cite: | Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs. Mol Plant, 14, 2021
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8IEW
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![BU of 8iew by Molmil](/molmil-images/mine/8iew) | Cas005-crRNA-DNA complex | Descriptor: | Cas005, DNA (55-MER), RNA (38-MER) | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | Deposit date: | 2023-02-16 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Cryo-EM structure of Cas005-crRNA-DNA complex at 3.1 Angstroms resolution To Be Published
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4O68
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![BU of 4o68 by Molmil](/molmil-images/mine/4o68) | Structure of human cyclic GMP-AMP synthase (cGAS) | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.436 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O67
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![BU of 4o67 by Molmil](/molmil-images/mine/4o67) | Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.444 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O69
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![BU of 4o69 by Molmil](/molmil-images/mine/4o69) | Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion | Descriptor: | Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.252 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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4O6A
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![BU of 4o6a by Molmil](/molmil-images/mine/4o6a) | Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA | Descriptor: | Cyclic GMP-AMP synthase, DNA1, DNA2, ... | Authors: | Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J. | Deposit date: | 2013-12-20 | Release date: | 2014-02-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.859 Å) | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop. Cell Rep, 6, 2014
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8HYR
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8I0V
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![BU of 8i0v by Molmil](/molmil-images/mine/8i0v) | The cryo-EM structure of human post-Bact complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Crooked neck-like protein 1, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2023-01-11 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8I0P
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![BU of 8i0p by Molmil](/molmil-images/mine/8i0p) | The cryo-EM structure of human pre-Bact complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2023-01-11 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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8I0W
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![BU of 8i0w by Molmil](/molmil-images/mine/8i0w) | The cryo-EM structure of human C complex | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Coiled-coil domain-containing protein 94, ... | Authors: | Zhan, X, Lu, Y, Shi, Y. | Deposit date: | 2023-01-11 | Release date: | 2024-07-31 | Last modified: | 2024-08-07 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for the activation of human spliceosome. Nat Commun, 15, 2024
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