5MUS
 
 | | Structure of the C-terminal domain of a reptarenavirus L protein | | Descriptor: | CHLORIDE ION, GLYCEROL, L protein | | Authors: | Rosenthal, M, Gogrefe, N, Reguera, J, Vogel, D, Rauschenberger, B, Cusack, S, Gunther, S, Reindl, S. | | Deposit date: | 2017-01-14 | | Release date: | 2017-05-17 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.009 Å) | | Cite: | Structural insights into reptarenavirus cap-snatching machinery.
PLoS Pathog., 13, 2017
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6J71
 | | HuA21-scFv in complex with the extracellular domain(ECD) of HER2 | | Descriptor: | Receptor tyrosine-protein kinase erbB-2, anti-HER2 humanized antibody HuA21, beta-D-mannopyranose, ... | | Authors: | Wang, Z, Guo, G, Cheng, B, Zhu, Z, Niu, L, Zhang, H. | | Deposit date: | 2019-01-16 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.918 Å) | | Cite: | Structural insight into a matured humanized monoclonal antibody HuA21 against HER2-overexpressing cancer cells.
Acta Crystallogr D Struct Biol, 75, 2019
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3PX7
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9LGN
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9LGV
 | | Crystal structure of human PKMYT1 protein kinase domain with Naphthyridinone Inhibitor compound 11 | | Descriptor: | 1,2-ETHANEDIOL, 3-azanyl-7-chloranyl-4-(7-fluoranyl-1H-indazol-4-yl)-1H-1,5-naphthyridin-2-one, L(+)-TARTARIC ACID, ... | | Authors: | Xu, Z.H, Chen, S. | | Deposit date: | 2025-01-10 | | Release date: | 2025-04-16 | | Last modified: | 2025-05-07 | | Method: | X-RAY DIFFRACTION (2.041 Å) | | Cite: | Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy.
J.Med.Chem., 68, 2025
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9LGL
 | | Crystal structure of human PKMYT1 protein kinase domain with Naphthyridinone Inhibitor compound 6 | | Descriptor: | 1,2-ETHANEDIOL, 3-azanyl-7-chloranyl-4-(2-methyl-5-oxidanyl-phenyl)-1H-1,5-naphthyridin-2-one, CHLORIDE ION, ... | | Authors: | Xu, Z.H, Chen, S. | | Deposit date: | 2025-01-10 | | Release date: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Discovery of Naphthyridinone Derivatives as Selective and Potent PKMYT1 Inhibitors with Antitumor Efficacy.
J.Med.Chem., 68, 2025
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9LID
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7U1Z
 | | Crystal structure of the DRBD and CROPs of TcdA | | Descriptor: | SULFATE ION, Toxin A | | Authors: | Baohua, C, Peng, C, Kay, P, Rongsheng, J. | | Deposit date: | 2022-02-22 | | Release date: | 2022-03-09 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.18 Å) | | Cite: | Structure and conformational dynamics of Clostridioides difficile toxin A.
Life Sci Alliance, 5, 2022
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4N78
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7U2P
 | | Structure of TcdA GTD in complex with RhoA | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Glucosyltransferase TcdA, MAGNESIUM ION, ... | | Authors: | Baohua, C, Zheng, L, Kay, P, Rongsheng, J. | | Deposit date: | 2022-02-24 | | Release date: | 2022-05-04 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.596 Å) | | Cite: | Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition.
Sci Rep, 12, 2022
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3J5S
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8HRI
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8HRJ
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8HRU
 | | Cryo-EM structure of ACE2 | | Descriptor: | Angiotensin-converting enzyme 2 | | Authors: | Xu, J, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-16 | | Release date: | 2023-12-20 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRK
 | | SARS-CoV-2 Delta S-RBD-ACE2 complex | | Descriptor: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | Authors: | Xu, J, Meng, F, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRM
 | | Cryo-EM structure of streptavidin | | Descriptor: | Streptavidin | | Authors: | Xu, J, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (2.56 Å) | | Cite: | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRN
 | | Cryo-EM structure of ACE2 | | Descriptor: | Angiotensin-converting enzyme 2 | | Authors: | Xu, J, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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8HRL
 | | SARS-CoV-2 Delta S-RBD-ACE2 | | Descriptor: | Processed angiotensin-converting enzyme 2, Spike protein S1 | | Authors: | Xu, J, Meng, F, Liu, N, Wang, H.W. | | Deposit date: | 2022-12-15 | | Release date: | 2023-12-20 | | Last modified: | 2025-01-01 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Self-assembled superstructure alleviates air-water interface effect in cryo-EM.
Nat Commun, 15, 2024
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7SH4
 | | CD1a-phosphatidylglycerol binary structure | | Descriptor: | (21R,24R,27S)-24,27,28-trihydroxy-18,24-dioxo-19,23,25-trioxa-24lambda~5~-phosphaoctacosan-21-yl (9Z)-octadec-9-enoate, 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | | Authors: | Wegrecki, M, Rossjohn, J. | | Deposit date: | 2021-10-07 | | Release date: | 2022-10-05 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a.
Nat.Immunol., 24, 2023
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6OQ7
 | | Structure of the GTD domain of Clostridium difficile toxin B in complex with VHH E3 | | Descriptor: | E3, MAGNESIUM ION, MANGANESE (II) ION, ... | | Authors: | Chen, P, Lam, K, Jin, R. | | Deposit date: | 2019-04-25 | | Release date: | 2019-07-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Structure of the full-length Clostridium difficile toxin B.
Nat.Struct.Mol.Biol., 26, 2019
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6OQ8
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6OQ6
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3FUS
 | | Improved Structure of the Unliganded Simian Immunodeficiency Virus gp120 Core | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Chen, X, Poon, B, Wang, Q, Ma, J. | | Deposit date: | 2009-01-14 | | Release date: | 2009-06-30 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural improvement of unliganded simian immunodeficiency virus gp120 core by normal-mode-based X-ray crystallographic refinement.
Acta Crystallogr.,Sect.D, 65, 2009
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8DW9
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8DXS
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