8DXS
Cryo-EM structure of RBD-directed neutralizing antibody P2B4 in complex with prefusion SARS-CoV-2 spike glycoprotein
Summary for 8DXS
Entry DOI | 10.2210/pdb8dxs/pdb |
EMDB information | 27775 |
Descriptor | Spike glycoprotein, P2B4 Heavy chain, P2B4 Light chain, ... (4 entities in total) |
Functional Keywords | neutralizing antibody, fusion protein, spike glycoprotein, covid-19, rbd, rbd-directed antibody, p2b4, viral protein, immune system, viral protein-immune system complex, viral protein/immune system |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 9 |
Total formula weight | 578863.38 |
Authors | Reddem, E.R.,Shapiro, L. (deposition date: 2022-08-03, release date: 2022-12-07, Last modification date: 2023-01-18) |
Primary citation | Luo, M.,Zhou, B.,Reddem, E.R.,Tang, B.,Chen, B.,Zhou, R.,Liu, H.,Liu, L.,Katsamba, P.S.,Au, K.K.,Man, H.O.,To, K.K.,Yuen, K.Y.,Shapiro, L.,Dang, S.,Ho, D.D.,Chen, Z. Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2. Emerg Microbes Infect, 12:2146538-2146538, 2023 Cited by PubMed: 36354024DOI: 10.1080/22221751.2022.2146538 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.76 Å) |
Structure validation
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