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5E98
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BU of 5e98 by Molmil
Crystal structure of human heparanase in complex with HepMer M04S02a
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heparanase, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E9C
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BU of 5e9c by Molmil
Crystal structure of human heparanase in complex with heparin tetrasaccharide dp4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E8M
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BU of 5e8m by Molmil
Crystal structure of human heparanase
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5E97
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BU of 5e97 by Molmil
Glycoside Hydrolase ligand structure 1
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Wu, L, Davies, G.J.
Deposit date:2015-10-14
Release date:2015-11-18
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structural characterization of human heparanase reveals insights into substrate recognition.
Nat.Struct.Mol.Biol., 22, 2015
5FFN
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BU of 5ffn by Molmil
Complex of subtilase SubTY from Bacillus sp. TY145 with chymotrypsin inhibitor CI2A
Descriptor: CALCIUM ION, Enzyme subtilase SubTY from Bacillus sp. TY145, SODIUM ION, ...
Authors:McAuley, K.E, Svendsen, A, Oestergaard, P.R, Dohnalek, J, Wilson, K.S.
Deposit date:2015-12-18
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Stabilization of Enzymes by Metal Binding: Structures of Two Alkalophilic Bacillus Subtilases and Analysis of the Second Metal-Binding Site of the Subtilase Family
Book, 2016
3W11
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BU of 3w11 by Molmil
Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ...
Authors:Lawrence, M.C, Smith, B.J.
Deposit date:2012-11-06
Release date:2013-01-09
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:How insulin engages its primary binding site on the insulin receptor
Nature, 493, 2013
1SQ6
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BU of 1sq6 by Molmil
Plasmodium falciparum homolog of Uridine phosphorylase/Purine nucleoside phosphorylase
Descriptor: SULFATE ION, uridine phosphorylase, putative
Authors:Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-03-17
Release date:2004-04-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine.
Acta Crystallogr.,Sect.D, 61, 2005
1MNK
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BU of 1mnk by Molmil
INTERACTIONS AMONG RESIDUES CD3, E7, E10 AND E11 IN MYOGLOBINS: ATTEMPTS TO SIMULATE THE O2 AND CO BINDING PROPERTIES OF APLYSIA MYOGLOBIN
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Krzywda, S, Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin.
Biochemistry, 34, 1995
1MNJ
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BU of 1mnj by Molmil
INTERACTIONS AMONG RESIDUES CD3, E7, E10 AND E11 IN MYOGLOBINS: ATTEMPTS TO SIMULATE THE O2 AND CO BINDING PROPERTIES OF APLYSIA MYOGLOBIN
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Krzywda, S, Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-04-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin.
Biochemistry, 34, 1995
1MNH
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BU of 1mnh by Molmil
INTERACTIONS AMONG RESIDUES CD3, E7, E10 AND E11 IN MYOGLOBINS: ATTEMPTS TO SIMULATE THE O2 AND CO BINDING PROPERTIES OF APLYSIA MYOGLOBIN
Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Davies, G.J, Wilkinson, A.J.
Deposit date:1995-01-11
Release date:1995-05-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Interactions among residues CD3, E7, E10, and E11 in myoglobins: attempts to simulate the ligand-binding properties of Aplysia myoglobin.
Biochemistry, 34, 1995
2M2N
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BU of 2m2n by Molmil
Structure of [L-HisB24] insulin analogue at pH 8.0
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-29
Release date:2013-03-06
Last modified:2013-06-05
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2O
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BU of 2m2o by Molmil
Structure of [D-HisB24] insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-29
Release date:2013-03-06
Last modified:2013-06-05
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2N2X
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BU of 2n2x by Molmil
Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Veverka, V, Hexnerova, R, Jiracek, J.
Deposit date:2015-05-15
Release date:2016-02-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2N2W
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BU of 2n2w by Molmil
Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 8.0
Descriptor: Insulin A chain, Insulin B chain
Authors:Veverka, V, Hexnerova, R, Jiracek, J.
Deposit date:2015-05-15
Release date:2016-02-03
Method:SOLUTION NMR
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2MPG
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BU of 2mpg by Molmil
Solution structure of the [AibB8,LysB28,ProB29]-insulin analogue
Descriptor: Insulin A chain, Insulin B chain
Authors:Kosinova, L, Jiracek, J, Zakova, L, Veverka, V.
Deposit date:2014-05-17
Release date:2014-06-11
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Insight into the structural and biological relevance of the T/R transition of the N-terminus of the B-chain in human insulin.
Biochemistry, 53, 2014
2N2V
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BU of 2n2v by Molmil
Solution structure of [B26-B29 triazole cross-linked]-insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Veverka, V, Hexnerova, R, Jiracek, J.
Deposit date:2015-05-15
Release date:2016-02-03
Method:SOLUTION NMR
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2M2M
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BU of 2m2m by Molmil
Structure of [L-HisB24] insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-28
Release date:2013-03-06
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2P
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BU of 2m2p by Molmil
Structure of [D-HisB24] insulin analogue at pH 8.0
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-29
Release date:2013-03-06
Last modified:2024-11-06
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
6TAA
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BU of 6taa by Molmil
STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD
Descriptor: ALPHA-AMYLASE, CALCIUM ION
Authors:Swift, H.J, Brady, L, Derewenda, Z.S, Dodson, E.J, Turkenburg, J.P, Wilkinson, A.J.
Deposit date:1992-08-21
Release date:1993-10-31
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991
2C0Y
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BU of 2c0y by Molmil
THE CRYSTAL STRUCTURE OF A CYS25ALA MUTANT OF HUMAN PROCATHEPSIN S
Descriptor: PROCATHEPSIN S
Authors:Kaulmann, G, Palm, G.J, Schilling, K, Hilgenfeld, R, Wiederanders, B.
Deposit date:2005-09-08
Release date:2006-11-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Crystal Structure of a Cys25 -> Ala Mutant of Human Procathepsin S Elucidates Enzyme-Prosequence Interactions.
Protein Sci., 15, 2006
1L2J
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BU of 1l2j by Molmil
Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol
Descriptor: (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, ESTROGEN RECEPTOR BETA
Authors:Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L.
Deposit date:2002-02-21
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.
Nat.Struct.Biol., 9, 2002
1JBU
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BU of 1jbu by Molmil
Coagulation Factor VII Zymogen (EGF2/Protease) in Complex with Inhibitory Exosite Peptide A-183
Descriptor: BENZAMIDINE, COAGULATION FACTOR VII, Peptide exosite inhibitor A-183, ...
Authors:Eigenbrot, C, Kirchhofer, D, Dennis, M.S, Santell, L, Lazarus, R.A, Stamos, J, Ultsch, M.H.
Deposit date:2001-06-06
Release date:2001-07-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The factor VII zymogen structure reveals reregistration of beta strands during activation.
Structure, 9, 2001

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