5E97

Glycoside Hydrolase ligand structure 1

Summary for 5E97

• Entry DOI: 10.2210/pdb5e97/pdb
• Descriptor: Heparanase, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: glycoside hydrolase, ligand 1, protein, sugar, hydrolase
• Biological source: Homo sapiens (Human); More
• Cellular location: Lysosome membrane; Peripheral membrane protein: Q9Y251 Q9Y251
• Total number of polymer chains: 2
• Total formula weight: 54218.49

Authors

Wu, L.,Davies, G.J. (deposition date: 2015-10-14, release date: 2015-11-18, Last modification date: 2024-01-10)

• Primary citation: Wu, L.,Viola, C.M.,Brzozowski, A.M.,Davies, G.J.; Structural characterization of human heparanase reveals insights into substrate recognition.; Nat.Struct.Mol.Biol., 22:1016-1022, 2015; PubMed: 26575439; DOI: 10.1038/nsmb.3136

Experimental method

X-RAY DIFFRACTION (1.63 Å)