5E97
Glycoside Hydrolase ligand structure 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heparanase | polymer | 389 | 43733.3 | 1 | UniProt (Q9Y251) Pfam (PF03662) In PDB | Homo sapiens (Human) | Endo-glucoronidase,Heparanase-1,Hpa1 |
2 | B | Heparanase | polymer | 77 | 8542.8 | 1 | UniProt (Q9Y251) In PDB | Homo sapiens (Human) | Endo-glucoronidase,Heparanase-1,Hpa1 |
3 | C | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid | branched | 776.6 | 1 | In PDB GlyTouCan (G35277LL) | |||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
6 | A | P-NITROPHENOL | non-polymer | 139.1 | 1 | Chemie (NPO) | |||
7 | water | water | 18.0 | 397 | Chemie (HOH) |
Sequence modifications
A: 158 - 543 (UniProt: Q9Y251)
B: 36 - 109 (UniProt: Q9Y251)
PDB | External Database | Details |
---|---|---|
Asp 155 | - | expression tag |
Pro 156 | - | expression tag |
Gly 157 | - | expression tag |
Arg 307 | Lys 307 | conflict |
PDB | External Database | Details |
---|---|---|
Asp 33 | - | expression tag |
Pro 34 | - | expression tag |
Gly 35 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 52276.1 | |
Branched | Number of molecules | 1 |
Total formula weight | 776.6 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1165.8 | |
All* | Total formula weight | 54218.5 |