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7E1A
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BU of 7e1a by Molmil
Human bile salt exporter ABCB11 in complex with taurocholate
Descriptor: Bile salt export pump, TAUROCHOLIC ACID
Authors:Wang, L, How, W.T, Chen, Y.
Deposit date:2021-02-01
Release date:2022-02-09
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets.
Cell Res., 32, 2022
3QUW
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BU of 3quw by Molmil
Crystal structure of yeast Mmf1
Descriptor: Protein MMF1
Authors:Jiang, Y.L, Pu, Y.G, Ma, X.X, Chen, Y, Zhou, C.Z.
Deposit date:2011-02-24
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures and putative interface of Saccharomyces cerevisiae mitochondrial matrix proteins Mmf1 and Mam33.
J.Struct.Biol., 175, 2011
7EHW
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BU of 7ehw by Molmil
BRD4-BD1 in complex with LT-642-602
Descriptor: 1-[4-ethyl-2-methyl-5-(6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
Authors:Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
Deposit date:2021-03-30
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:BRD4-BD1 in complex with LT-642-602
To Be Published
7EHY
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BU of 7ehy by Molmil
BRD4-BD1 in complex with LT-448-138
Descriptor: 1-[2,4-dimethyl-5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
Authors:Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
Deposit date:2021-03-30
Release date:2022-03-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:BRD4-BD1 in complex with LT-642-602
To Be Published
7EIG
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BU of 7eig by Molmil
BRD4-BD1 in complex with LT-730-903
Descriptor: 1-[5-(5-azanyl-1H-benzimidazol-2-yl)-2-methyl-4-phenyl-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
Authors:Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
Deposit date:2021-03-31
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:BRD4-BD1 in complex with LT-730-903
To Be Published
7EIK
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BU of 7eik by Molmil
RD4-BD1 in complex with LT-872-297
Descriptor: 1-[2-methyl-5-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-4-(1-methylpyrazol-4-yl)-1H-pyrrol-3-yl]ethanone, Bromodomain-containing protein 4
Authors:Zheng, W, Kong, B, Tang, W, Zhu, J, Chen, Y.
Deposit date:2021-03-31
Release date:2022-04-06
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:RD4-BD1 in complex with LT-872-297
To Be Published
2FA4
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BU of 2fa4 by Molmil
Crystal Structure of Oxidized Form from Saccharomyces cerevisiae
Descriptor: Thioredoxin II
Authors:Bao, R, Tang, Y.J, Zhou, C.Z, Chen, Y.
Deposit date:2005-12-06
Release date:2006-12-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Crystal structure of the yeast cytoplasmic thioredoxin Trx2
Proteins, 66, 2007
3RD6
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BU of 3rd6 by Molmil
Crystal structure of Mll3558 protein from Rhizobium loti. Northeast Structural Genomics Consortium target id MlR403
Descriptor: Mll3558 protein
Authors:Seetharaman, J, Chen, Y, Wang, D, Ciccosanti, C, Sahdev, S, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-04-01
Release date:2011-05-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Mll3558 protein from Rhizobium loti. Northeast Structural Genomics Consortium target id MlR403
To be Published
3PIL
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BU of 3pil by Molmil
Crystal structure of Mxr1 from Saccharomyces cerevisiae in reduced form
Descriptor: ACETATE ION, Peptide methionine sulfoxide reductase
Authors:Ma, X.X, Guo, P.C, Shi, W.W, Luo, M, Tan, X.F, Chen, Y, Zhou, C.Z.
Deposit date:2010-11-07
Release date:2011-02-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural plasticity of the thioredoxin recognition site of yeast methionine S-sulfoxide reductase Mxr1
J.Biol.Chem., 286, 2011
2F9C
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BU of 2f9c by Molmil
Crystal structure of YDCK from Salmonella cholerae. NESG target SCR6
Descriptor: CESIUM ION, Hypothetical protein YDCK
Authors:Benach, J, Chen, Y, Vorobiev, S.M, Seetharaman, J, Janjua, H, Cooper, B, Acton, X.T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-12-05
Release date:2005-12-20
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of YDCK from Salmonella cholerae NESG target SCR6.
To be Published
2ZNC
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BU of 2znc by Molmil
MURINE CARBONIC ANHYDRASE IV
Descriptor: CARBONIC ANHYDRASE IV, ZINC ION
Authors:Stams, T, Chen, Y, Christianson, D.W.
Deposit date:1998-02-10
Release date:1999-03-23
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
Protein Sci., 7, 1998
3NXH
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BU of 3nxh by Molmil
Crystal Structure of the transcriptional regulator yvhJ from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR735.
Descriptor: transcriptional regulator yvhJ
Authors:Vorobiev, S, Chen, Y, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2010-07-13
Release date:2010-08-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.584 Å)
Cite:Crystal Structure of the transcriptional regulator yvhJ from Bacillus subtilis.
To be Published
3IPM
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BU of 3ipm by Molmil
Crystal Structure of Archaeal 20S Proteasome in Complex with the C-terminus of PAN
Descriptor: Proteasome activator PA26, Proteasome-activating nucleotidase fusion protein, Proteasome subunit alpha, ...
Authors:Yu, Y, Cheng, Y.
Deposit date:2009-08-17
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (4 Å)
Cite:Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.
Embo J., 29, 2010
3B55
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BU of 3b55 by Molmil
Crystal structure of the Q81BN2_BACCR protein from Bacillus cereus. NESG target BcR135
Descriptor: CALCIUM ION, Succinoglycan biosynthesis protein
Authors:Vorobiev, S.M, Chen, Y, Kuzin, A.P, Seetharaman, J, Wang, H, Cunningham, K, Owens, L, Maglaqui, M, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-10-25
Release date:2007-11-06
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the Q81BN2_BACCR protein from Bacillus cereus.
To be Published
1Q57
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BU of 1q57 by Molmil
The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Descriptor: DNA primase/helicase
Authors:Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T.
Deposit date:2003-08-06
Release date:2003-11-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
3C3D
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BU of 3c3d by Molmil
Crystal structure of 2-phospho-(S)-lactate transferase from Methanosarcina mazei in complex with Fo and phosphate. Northeast Structural Genomics Consortium target MaR46
Descriptor: 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, 2-phospho-L-lactate transferase, PHOSPHATE ION
Authors:Forouhar, F, Abashidze, M, Xu, H, Grochowski, L.L, Seetharaman, J, Hussain, M, Kuzin, A.P, Chen, Y, Zhou, W, Xiao, R, Acton, T.B, Montelione, G.T, Galinier, A, White, R.H, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2008-01-28
Release date:2008-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular insights into the biosynthesis of the f420 coenzyme.
J.Biol.Chem., 283, 2008
6KMJ
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BU of 6kmj by Molmil
Crystal structure of Sth1 bromodomain in complex with H3K14Ac
Descriptor: GLYCEROL, Histone H3, Nuclear protein STH1/NPS1
Authors:Chen, G, Li, W, Yan, F, Wang, D, Chen, Y.
Deposit date:2019-07-31
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex.
Structure, 28, 2020
6KMB
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BU of 6kmb by Molmil
Crystal structure of Sth1 bromodomain
Descriptor: GLYCEROL, Nuclear protein STH1/NPS1
Authors:Chen, G, Li, W, Yan, F, Wang, D, Chen, Y.
Deposit date:2019-07-31
Release date:2019-10-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis for Specific Recognition of H3K14 Acetylation by Sth1 in the RSC Chromatin Remodeling Complex.
Structure, 28, 2020
2ME3
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BU of 2me3 by Molmil
HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle
Descriptor: Envelope glycoprotein gp160
Authors:Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W.
Deposit date:2013-09-20
Release date:2013-10-09
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
1DT1
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BU of 1dt1 by Molmil
THERMUS THERMOPHILUS CYTOCHROME C552 SYNTHESIZED BY ESCHERICHIA COLI
Descriptor: CYTOCHROME C552, HEME C
Authors:Fee, J.A, Chen, Y, Hill, M.J, Gomez-Moran, E, Loehr, T, Ai, J, Thony-Meyer, L, Williams, P.A, Stura, E, Sridhar, V, McRee, D.E.
Deposit date:2000-01-10
Release date:2000-02-18
Last modified:2021-03-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Integrity of thermus thermophilus cytochrome c552 synthesized by Escherichia coli cells expressing the host-specific cytochrome c maturation genes, ccmABCDEFGH: biochemical, spectral, and structural characterization of the recombinant protein.
Protein Sci., 9, 2000
3J94
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BU of 3j94 by Molmil
Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase
Authors:Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J97
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BU of 3j97 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II)
Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
Authors:Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J98
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BU of 3j98 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)
Descriptor: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
Authors:Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
Deposit date:2014-12-05
Release date:2015-01-28
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (8.4 Å)
Cite:Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J5R
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BU of 3j5r by Molmil
Reconstruction of TRPV1 ion channel in complex with capsaicin by single particle cryo-microscopy
Descriptor: Transient receptor potential cation channel subfamily V member 1
Authors:Liao, M, Cao, E, Julius, D, Cheng, Y.
Deposit date:2013-10-28
Release date:2013-12-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:TRPV1 structures in distinct conformations reveal activation mechanisms.
Nature, 504, 2013
6LR0
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BU of 6lr0 by Molmil
structure of human bile salt exporter ABCB11
Descriptor: Bile salt export pump
Authors:Wang, L, Hou, W.T, Chen, L, Jiang, Y.L, Xu, D, Sun, L.F, Zhou, C.Z, Chen, Y.
Deposit date:2020-01-15
Release date:2020-04-15
Last modified:2023-01-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of human bile salts exporter ABCB11.
Cell Res., 30, 2020

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