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8TM2
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BU of 8tm2 by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TLZ
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BU of 8tlz by Molmil
Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: (2S)-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8VM1
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BU of 8vm1 by Molmil
Structural Elucidation of the Mesothelin Mucin16 CA125 Interaction
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Mesothelin, cleaved form,Mucin-16, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2024-01-12
Release date:2024-09-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural elucidation of the mesothelin-mucin-16/CA125 interaction.
Structure, 32, 2024
3MDS
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BU of 3mds by Molmil
MAGANESE SUPEROXIDE DISMUTASE FROM THERMUS THERMOPHILUS
Descriptor: MANGANESE (III) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Ludwig, M.L, Metzger, A.L, Pattridge, K.A, Stallings, W.C.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Manganese superoxide dismutase from Thermus thermophilus. A structural model refined at 1.8 A resolution.
J.Mol.Biol., 219, 1991
4LRN
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BU of 4lrn by Molmil
Ontogeny of recognition specificity and functionality for the anti-HIV antibody 4E10
Descriptor: GEP 1 heavy chain, GEP 1 light chain
Authors:Finton, K.A.K.
Deposit date:2013-07-20
Release date:2014-10-08
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
7SJQ
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BU of 7sjq by Molmil
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine-dense peptide, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2021-10-18
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
1B3J
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BU of 1b3j by Molmil
STRUCTURE OF THE MHC CLASS I HOMOLOG MIC-A, A GAMMADELTA T CELL LIGAND
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS I HOMOLOG MIC-A
Authors:Li, P, Willie, S, Bauer, S, Morris, D, Spies, T, Strong, R.
Deposit date:1998-12-11
Release date:1999-07-09
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand.
Immunity, 10, 1999
1MNG
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BU of 1mng by Molmil
STRUCTURE-FUNCTION IN E. COLI IRON SUPEROXIDE DISMUTASE: COMPARISONS WITH THE MANGANESE ENZYME FROM T. THERMOPHILUS
Descriptor: AZIDE ION, MANGANESE (II) ION, MANGANESE SUPEROXIDE DISMUTASE
Authors:Lah, M.S, Dixon, M, Pattridge, K.A, Stallings, W.C, Fee, J.A, Ludwig, M.L.
Deposit date:1994-07-13
Release date:1994-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure-function in Escherichia coli iron superoxide dismutase: comparisons with the manganese enzyme from Thermus thermophilus.
Biochemistry, 34, 1995
4ODX
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BU of 4odx by Molmil
4E10 germline encoded precursor no.7 in complex with epitope scaffold T117
Descriptor: 4E10 epitope scaffold T117, GEP7 Fv heavy chain, GEP7 Fv light chain
Authors:Finton, K.A.K.
Deposit date:2014-01-10
Release date:2014-10-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
4OB5
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BU of 4ob5 by Molmil
Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10
Descriptor: 4E10 antibody germline precursor 7 heavy chain Fv, 4E10 antibody germline precursor 7 light chain Fv, GLYCEROL, ...
Authors:Jaffe, J.B, Rupert, P.B.
Deposit date:2014-01-06
Release date:2014-10-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10.
Plos Pathog., 10, 2014
6OL5
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BU of 6ol5 by Molmil
Structure of iglb12 Fab in complex with anti-idiotype ib3 Fab
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, AMMONIUM ION, CHLORIDE ION, ...
Authors:Weidle, C, Pancera, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
6OL6
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BU of 6ol6 by Molmil
Structure of iglb12 scFv in complex with anti-idiotype ib2 Fab
Descriptor: CHLORIDE ION, ib2 Heavy Chain, ib2 Light Chain, ...
Authors:Weidle, C, Pancera, M, Gewe, M.
Deposit date:2019-04-15
Release date:2019-07-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes.
J.Exp.Med., 216, 2019
7U61
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BU of 7u61 by Molmil
Crystal Structure of Anti-Nicotine Antibody NIC311 Fab Complexed with Nicotine
Descriptor: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, NIC311 Fab Heavy Chain, NIC311 Fab Light Chain, ...
Authors:Rodarte, J.V, Pancera, M.P, Liban, T.L.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U62
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BU of 7u62 by Molmil
Crystal structure of Anti-Heroin Antibody HY4-1F9 Fab Complexed with Morphine
Descriptor: (7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL, ACETATE ION, HY4-1F9 Fab Heavy Chain, ...
Authors:Rodarte, J.V, Pancera, M.P.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
7U64
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BU of 7u64 by Molmil
Crystal Structure of Anti-Fentanyl Antibody HY6-F9.6 Fab Complexed with Fentanyl
Descriptor: ACETATE ION, HY6-F9.6 Fab heavy chain, HY6-F9.6 Fab light chain, ...
Authors:Rodarte, J.V, Pancera, M.P.
Deposit date:2022-03-03
Release date:2023-01-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding.
Structure, 31, 2023
3LRR
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BU of 3lrr by Molmil
Crystal structure of human RIG-I CTD bound to a 12 bp AU rich 5' ppp dsRNA
Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-02-11
Release date:2010-06-02
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
3LEF
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BU of 3lef by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1Z6NA_001
Descriptor: 1,2-ETHANEDIOL, Uncharacterized protein 4E10_S0_1Z6NA_001 (T18)
Authors:Holmes, M.A.
Deposit date:2010-01-14
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF6
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BU of 3lf6 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1XIZA_S0_001_N
Descriptor: PHOSPHATE ION, Putative phosphotransferase system
Authors:Holmes, M.A.
Deposit date:2010-01-15
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LG7
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BU of 3lg7 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_S0_1EZ3A_002_C
Descriptor: 4E10_S0_1EZ3A_002_C (T246), SULFATE ION
Authors:Holmes, M.A.
Deposit date:2010-01-19
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LHP
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BU of 3lhp by Molmil
Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex
Descriptor: 1,2-ETHANEDIOL, 4E10_D0_1ISEA_004_N (T93), Fv 4E10 heavy chain, ...
Authors:Holmes, M.A.
Deposit date:2010-01-22
Release date:2010-09-22
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LH2
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BU of 3lh2 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex
Descriptor: 4E10_1VI7A_S0_002_N (T88), Fv 4E10 heavy chain, Fv 4E10 light chain
Authors:Holmes, M.A.
Deposit date:2010-01-21
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LF9
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BU of 3lf9 by Molmil
Crystal structure of HIV epitope-scaffold 4E10_D0_1IS1A_001_C
Descriptor: 4E10_D0_1IS1A_001_C (T161)
Authors:Holmes, M.A.
Deposit date:2010-01-16
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18, 2010
3LRN
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BU of 3lrn by Molmil
Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA
Descriptor: Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION
Authors:Li, P.
Deposit date:2010-02-11
Release date:2010-06-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
7SQP
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BU of 7sqp by Molmil
Single chain trimer HLA-A*02:01 (Y108C) with HPV.16 E7 peptide YMLDLQPETTDL
Descriptor: Protein E7 peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-05
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023
7SRK
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BU of 7srk by Molmil
Single chain trimer HLA-A*24:02 (Y108C, A163C) with 8mer peptide YPPVPETF
Descriptor: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH
Authors:Finton, K.A.K, Rupert, P.B.
Deposit date:2021-11-08
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Effects of HLA single chain trimer design on peptide presentation and stability.
Front Immunol, 14, 2023

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