Crystal structure of HIV epitope-scaffold 4E10_D0_1ISEA_004_N 4E10 Fv complex

Summary for 3LHP

Related3LEF 3LF6 3LG7 3LH2 3LHP
DescriptorFv 4E10 heavy chain, Fv 4E10 light chain, 4E10_D0_1ISEA_004_N (T93), ... (5 entities in total)
Functional Keywordsepitope-scaffold, immune system
Biological sourceHomo sapiens
Total number of polymer chains6
Total molecular weight82202.39
Holmes, M.A. (deposition date: 2010-01-22, release date: 2010-09-22, Last modification date: 2011-07-13)
Primary citation
Correia, B.E.,Ban, Y.E.,Holmes, M.A.,Xu, H.,Ellingson, K.,Kraft, Z.,Carrico, C.,Boni, E.,Sather, D.N.,Zenobia, C.,Burke, K.Y.,Bradley-Hewitt, T.,Bruhn-Johannsen, J.F.,Kalyuzhniy, O.,Baker, D.,Strong, R.K.,Stamatatos, L.,Schief, W.R.
Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope.
Structure, 18:1116-1126, 2010
PubMed: 20826338 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2010.06.010
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.334806.4%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution