7U64
Crystal Structure of Anti-Fentanyl Antibody HY6-F9.6 Fab Complexed with Fentanyl
Summary for 7U64
Entry DOI | 10.2210/pdb7u64/pdb |
Descriptor | HY6-F9.6 Fab heavy chain, HY6-F9.6 Fab light chain, N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide, ... (6 entities in total) |
Functional Keywords | mab, opioid, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 18 |
Total formula weight | 441946.41 |
Authors | Rodarte, J.V.,Pancera, M.P. (deposition date: 2022-03-03, release date: 2023-01-11, Last modification date: 2023-10-25) |
Primary citation | Rodarte, J.V.,Baehr, C.,Hicks, D.,Liban, T.L.,Weidle, C.,Rupert, P.B.,Jahan, R.,Wall, A.,McGuire, A.T.,Strong, R.K.,Runyon, S.,Pravetoni, M.,Pancera, M. Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding. Structure, 31:20-32.e5, 2023 Cited by PubMed: 36513069DOI: 10.1016/j.str.2022.11.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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