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6B7Z
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BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
Descriptor: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-05
Release date:2018-01-10
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
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BU of 6bf9 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Descriptor: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
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BU of 6bf7 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Descriptor: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
8H55
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BU of 8h55 by Molmil
The structure of zebrafish angiotensinogen
Descriptor: Angiotensinogen, SULFATE ION
Authors:Zhou, A, Wei, H.
Deposit date:2022-10-12
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:BIOLOGICAL IMPLICATIONS OF A 2 ANGSTROMS STRUCTURE OF DIMERIC ANGIOTENSINOGEN
To Be Published
8INJ
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BU of 8inj by Molmil
Crystal structure of UGT74AN3-UDP-DIG
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIGITOXIGENIN, Glycosyltransferase, ...
Authors:Feng, L, Wei, H.
Deposit date:2023-03-10
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Crystal structure of UGT74AN3-UDP-DIG
To Be Published
8IWK
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BU of 8iwk by Molmil
ABCG25 Wild Type purified with DDM plus CHS in ABA-bound state
Descriptor: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, ABC transporter G family member 25
Authors:Sun, L, Liu, X, Ying, W, Liao, L, Wei, H.
Deposit date:2023-03-30
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:ABCG25 Wild Type purified with DDM plus CHS in ABA-bound state
To Be Published
8IWJ
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BU of 8iwj by Molmil
ABCG25 Wild Type in Apo-state
Descriptor: ABC transporter G family member 25
Authors:Sun, L, Liu, X, Ying, W, Liao, L, Wei, H.
Deposit date:2023-03-30
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:ABCG25 Wild Type in Apo-state
To Be Published
8IWN
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BU of 8iwn by Molmil
ABCG25 EQ mutant in ATP-bound state
Descriptor: ABC transporter G family member 25, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Sun, L, Liu, X, Ying, W, Liao, L, Wei, H.
Deposit date:2023-03-30
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:ABCG25 EQ mutant in ATP-bound state
To Be Published
7W11
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BU of 7w11 by Molmil
glycosyltransferase
Descriptor: DIGITOXIGENIN, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, ...
Authors:Wei, H, Feng, L.
Deposit date:2021-11-19
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W0K
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BU of 7w0k by Molmil
plant glycosyltransferase
Descriptor: GLYCEROL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE
Authors:Wei, H, Feng, L.
Deposit date:2021-11-18
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W1H
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BU of 7w1h by Molmil
glycosyltransferase
Descriptor: Glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Wei, H, Feng, L.
Deposit date:2021-11-19
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W1B
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BU of 7w1b by Molmil
Glycosyltransferase
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIGITOXIGENIN, Glycosyltransferase, ...
Authors:Wei, H, Feng, L.
Deposit date:2021-11-19
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W09
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BU of 7w09 by Molmil
UGT74AN2, Plant Steroid Glycosyltransferase
Descriptor: Glycosyltransferase
Authors:Wei, H, Feng, L.
Deposit date:2021-11-18
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W10
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BU of 7w10 by Molmil
UGT74AN2
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE, ...
Authors:Wei, H, Long, F.
Deposit date:2021-11-18
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
7W0Z
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BU of 7w0z by Molmil
Glycosyltranferase UGT74AN2
Descriptor: 5-[(1R,2S,4R,6R,7R,10S,11S,14S,16R)-14-hydroxy-7,11-dimethyl-3-oxapentacyclo[8.8.0.02,4.02,7.011,16]octadecan-6-yl]pyran-2-one, Glycosyltransferase, URIDINE-5'-DIPHOSPHATE
Authors:Wei, H, Feng, L.
Deposit date:2021-11-18
Release date:2022-03-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Functional and Structural Dissection of a Plant Steroid 3-O-Glycosyltransferase Facilitated the Engineering Enhancement of Sugar Donor Promiscuity
Acs Catalysis, 2022
5IP0
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BU of 5ip0 by Molmil
PHA Binding Protein PhaP (Phasin)
Descriptor: CADMIUM ION, PHA granule-associated protein
Authors:Chen, G.Q, Wang, X.Q, Zhao, H.Y.
Deposit date:2016-03-09
Release date:2017-01-25
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Insights on PHA Binding Protein PhaP from Aeromonas hydrophila
Sci Rep, 6, 2016
6OT1
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BU of 6ot1 by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-08-07
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6OSY
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BU of 6osy by Molmil
Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122
Descriptor: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Gorman, J, Kwong, P.D.
Deposit date:2019-05-02
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6XOS
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BU of 6xos by Molmil
CryoEM structure of human presequence protease in partial open state 1
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOU
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BU of 6xou by Molmil
CryoEM structure of human presequence protease in open state
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOV
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BU of 6xov by Molmil
CryoEM structure of human presequence protease in partial closed state 1
Descriptor: Amyloid-beta precursor protein, Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
6XOT
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BU of 6xot by Molmil
CryoEM structure of human presequence protease in partial open state 2
Descriptor: Presequence protease, mitochondrial
Authors:Liang, W.G, Zhao, M, Tang, W.
Deposit date:2020-07-07
Release date:2021-07-07
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition.
Nat Commun, 13, 2022
8XLO
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BU of 8xlo by Molmil
FGFR1 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 1, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024
8XLQ
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BU of 8xlq by Molmil
FGFR4 kinase domain with a dual-warhead covalent inhibitor CXF-007
Descriptor: CXF007, Fibroblast growth factor receptor 4, SULFATE ION
Authors:Chen, X.J, Chen, Y.H.
Deposit date:2023-12-26
Release date:2024-03-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Design, synthesis, and biological evaluation of selective covalent inhibitors of FGFR4.
Eur.J.Med.Chem., 268, 2024
8JMZ
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BU of 8jmz by Molmil
FGFR1 kinase domain with sulfatinib
Descriptor: Fibroblast growth factor receptor 1, GLYCEROL, N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide, ...
Authors:Chen, X.J, Lin, Q.M, Chen, Y.H.
Deposit date:2023-06-05
Release date:2024-03-27
Method:X-RAY DIFFRACTION (1.988 Å)
Cite:Structural basis and selectivity of sulfatinib binding to FGFR and CSF-1R.
Commun Chem, 7, 2024

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