6AKO

Crystal Structure of FOXC2 DBD Bound to DBE2 DNA

Summary for 6AKO

• Entry DOI: 10.2210/pdb6ako/pdb
• Descriptor: DNA (5'-D(CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3'), DNA (5'-D(TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3'), Forkhead box protein C2, ... (5 entities in total)
• Functional Keywords: foxc; dna binding domain; dna recognition; crystal structure; lymphoedema distichiasis syndrome, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 22146.90

Authors

Chen, X.,Wei, H.,Li, J.,Liang, X.,Dai, S.,Jiang, L.,Guo, M.,Chen, Y. (deposition date: 2018-09-03, release date: 2019-02-06, Last modification date: 2023-11-22)

• Primary citation: Chen, X.,Wei, H.,Li, J.,Liang, X.,Dai, S.,Jiang, L.,Guo, M.,Qu, L.,Chen, Z.,Chen, L.,Chen, Y.; Structural basis for DNA recognition by FOXC2.; Nucleic Acids Res., 47:3752-3764, 2019; PubMed: 30722065; DOI: 10.1093/nar/gkz077

Experimental method

X-RAY DIFFRACTION (2.396 Å)