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6AKO

Crystal Structure of FOXC2 DBD Bound to DBE2 DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA (5'-D(CP*AP*AP*AP*AP*TP*GP*TP*AP*AP*AP*CP*AP*AP*GP*A)-3')polymer164932.31Homo sapiens
2B
(B)
DNA (5'-D(TP*CP*TP*TP*GP*TP*TP*TP*AP*CP*AP*TP*TP*TP*TP*G)-3')polymer164860.21Homo sapiens
3C
(C)
Forkhead box protein C2polymer10312330.21UniProt (Q99958)
Pfam (PF00250)
Homo sapiens (Human)Forkhead-related protein FKHL14,Mesenchyme fork head protein 1,MFH-1 protein,Transcription factor FKH-14
4D
(C)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, F
(B, C)
waterwater18.010Chemie (HOH)
Sequence modifications
C: 72 - 172 (UniProt: Q99958)
PDBExternal DatabaseDetails
Gly 70-expression tag
Pro 71-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight22122.6
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight22146.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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