4HO9
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![BU of 4ho9 by Molmil](/molmil-images/mine/4ho9) | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP | Descriptor: | GALACTOSE-URIDINE-5'-DIPHOSPHATE, Glucose-1-phosphate thymidylyltransferase, SULFATE ION, ... | Authors: | Chen, T.J, Chien, W.T, Lin, C.C, Wang, W.C. | Deposit date: | 2012-10-22 | Release date: | 2013-10-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of glucose 1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus complexed with UDP-galactose and UTP TO BE PUBLISHED
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1A1T
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![BU of 1a1t by Molmil](/molmil-images/mine/1a1t) | STRUCTURE OF THE HIV-1 NUCLEOCAPSID PROTEIN BOUND TO THE SL3 PSI-RNA RECOGNITION ELEMENT, NMR, 25 STRUCTURES | Descriptor: | NUCLEOCAPSID PROTEIN, SL3 STEM-LOOP RNA, ZINC ION | Authors: | De Guzman, R.N, Wu, Z.R, Stalling, C.C, Pappalardo, L, Borer, P.N, Summers, M.F. | Deposit date: | 1997-12-15 | Release date: | 1998-06-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the HIV-1 nucleocapsid protein bound to the SL3 psi-RNA recognition element. Science, 279, 1998
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6KDL
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![BU of 6kdl by Molmil](/molmil-images/mine/6kdl) | Crystal structure of human DNMT3B-DNMT3L complex (I) | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.274 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDP
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![BU of 6kdp by Molmil](/molmil-images/mine/6kdp) | Crystal structure of human DNMT3B-DNMT3L complex (II) | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDB
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![BU of 6kdb by Molmil](/molmil-images/mine/6kdb) | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-01 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.862 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDT
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![BU of 6kdt by Molmil](/molmil-images/mine/6kdt) | Crystal structure of human DNMT3B (Q772R)-DNMT3L complex | Descriptor: | DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, FORMIC ACID, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-02 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6KDA
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![BU of 6kda by Molmil](/molmil-images/mine/6kda) | Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpG site | Descriptor: | DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ... | Authors: | Lin, C.-C, Chen, Y.-P, Yang, W.-Z, Shen, C.-K, Yuan, H.S. | Deposit date: | 2019-07-01 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.909 Å) | Cite: | Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B. Nucleic Acids Res., 48, 2020
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6V6Q
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![BU of 6v6q by Molmil](/molmil-images/mine/6v6q) | Crystal Structure of Monophosphorylated FGF Receptor 2 isoform IIIb with PTR657 | Descriptor: | Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Lin, C.-C, Wieteska, L, Poncet-Montange, G, Suen, K.M, Arold, S.T, Ahmed, Z, Ladbury, J.E. | Deposit date: | 2019-12-05 | Release date: | 2020-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | The combined action of the intracellular regions regulates FGFR2 kinase activity Commun Biol, 6, 2023
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3T8S
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![BU of 3t8s by Molmil](/molmil-images/mine/3t8s) | Apo and InsP3-bound Crystal Structures of the Ligand-Binding Domain of an InsP3 Receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 | Authors: | Lin, C, Baek, K, Lu, Z. | Deposit date: | 2011-08-01 | Release date: | 2011-09-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.77 Å) | Cite: | Apo and InsP(3)-bound crystal structures of the ligand-binding domain of an InsP(3) receptor. Nat.Struct.Mol.Biol., 18, 2011
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3EGA
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![BU of 3ega by Molmil](/molmil-images/mine/3ega) | |
3EGB
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![BU of 3egb by Molmil](/molmil-images/mine/3egb) | |
4WIZ
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![BU of 4wiz by Molmil](/molmil-images/mine/4wiz) | Crystal structure of Grouper nervous necrosis virus-like particle at 3.6A | Descriptor: | CALCIUM ION, Coat protein | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | Deposit date: | 2014-09-28 | Release date: | 2015-10-07 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection Plos Pathog., 11, 2015
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4RFU
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![BU of 4rfu by Molmil](/molmil-images/mine/4rfu) | Crystal structure of truncated P-domain from Grouper nervous necrosis virus capsid protein at 1.2A | Descriptor: | CALCIUM ION, Coat protein, DI(HYDROXYETHYL)ETHER, ... | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | Deposit date: | 2014-09-27 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection Plos Pathog., 11, 2015
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4RFT
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![BU of 4rft by Molmil](/molmil-images/mine/4rft) | T=1 subviral particle of Grouper nervous necrosis virus capsid protein deletion mutant (delta 1-34 & 218-338) | Descriptor: | Coat protein | Authors: | Chen, N.C, Chen, C.J, Yoshimura, M, Guan, H.H, Chen, T.Y. | Deposit date: | 2014-09-27 | Release date: | 2015-10-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection Plos Pathog., 11, 2015
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7OZD
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![BU of 7ozd by Molmil](/molmil-images/mine/7ozd) | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 34. | Descriptor: | 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-[6-(4-hydroxyphenyl)-1H-indazol-3-yl]benzamide, ... | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | Deposit date: | 2021-06-27 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J.Med.Chem., 65, 2022
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7OZB
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![BU of 7ozb by Molmil](/molmil-images/mine/7ozb) | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 38. | Descriptor: | 1,2-ETHANEDIOL, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol, Fibroblast growth factor receptor 1, ... | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | Deposit date: | 2021-06-27 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J.Med.Chem., 65, 2022
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7OZF
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![BU of 7ozf by Molmil](/molmil-images/mine/7ozf) | FGFR1 kinase domain (residues 458-765) with mutations C488A, C584S in complex with 19. | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Fibroblast growth factor receptor 1, ... | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | Deposit date: | 2021-06-28 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J.Med.Chem., 65, 2022
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7OZY
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![BU of 7ozy by Molmil](/molmil-images/mine/7ozy) | FGFR2 kinase domain (residues 461-763) in complex with 38. | Descriptor: | 1,2-ETHANEDIOL, 4-[3-(4-piperazin-4-ium-1-ylphenyl)-1H-indazol-6-yl]phenol, Fibroblast growth factor receptor 2, ... | Authors: | Trinh, C.H, Turner, L.D, Fishwick, C.W.G. | Deposit date: | 2021-06-29 | Release date: | 2021-12-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J.Med.Chem., 65, 2022
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5VXA
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![BU of 5vxa by Molmil](/molmil-images/mine/5vxa) | Structure of the human Mesh1-NADPH complex | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... | Authors: | Rose, J, Zhou, P. | Deposit date: | 2017-05-23 | Release date: | 2018-05-23 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis. Nat Metab, 2, 2020
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5XMJ
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![BU of 5xmj by Molmil](/molmil-images/mine/5xmj) | Crystal structure of quinol:fumarate reductase from Desulfovibrio gigas | Descriptor: | DODECYL-BETA-D-MALTOSIDE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Guan, H.H, Hsieh, Y.C, Lin, P.R, Chen, C.J. | Deposit date: | 2017-05-15 | Release date: | 2018-06-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural insights into the electron/proton transfer pathways in the quinol:fumarate reductase from Desulfovibrio gigas. Sci Rep, 8, 2018
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6DC4
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![BU of 6dc4 by Molmil](/molmil-images/mine/6dc4) | RSV-neutralizing human antibody AM22 | Descriptor: | 1,2-ETHANEDIOL, Fab AM22 Heavy Chain, Fab AM22 Light Chain | Authors: | Jones, H.G, McLellan, J.S. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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6DC3
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![BU of 6dc3 by Molmil](/molmil-images/mine/6dc3) | RSV prefusion F bound to RSD5 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ... | Authors: | Battles, M.B, McLellan, J.S, Jones, H.J. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.501 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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6DC5
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![BU of 6dc5 by Molmil](/molmil-images/mine/6dc5) | RSV prefusion F in complex with AM22 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Jones, H.G, McLellan, J.S. | Deposit date: | 2018-05-04 | Release date: | 2019-07-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
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5VTB
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![BU of 5vtb by Molmil](/molmil-images/mine/5vtb) | Crystal structure of RBBP4 bound to BCL11a peptide | Descriptor: | B-cell lymphoma/leukemia 11A, GLYCEROL, Histone-binding protein RBBP4 | Authors: | Meagher, J.L, Stuckey, J.A. | Deposit date: | 2017-05-16 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes. J. Biol. Chem., 293, 2018
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7CRA
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![BU of 7cra by Molmil](/molmil-images/mine/7cra) | |