5VXA
Structure of the human Mesh1-NADPH complex
Summary for 5VXA
Entry DOI | 10.2210/pdb5vxa/pdb |
Descriptor | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1, ZINC ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (8 entities in total) |
Functional Keywords | mesh1 nadph, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 43137.83 |
Authors | |
Primary citation | Ding, C.C.,Rose, J.,Sun, T.,Wu, J.,Chen, P.H.,Lin, C.C.,Yang, W.H.,Chen, K.Y.,Lee, H.,Xu, E.,Tian, S.,Akinwuntan, J.,Zhao, J.,Guan, Z.,Zhou, P.,Chi, J.T. MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis. Nat Metab, 2:270-277, 2020 Cited by PubMed: 32462112DOI: 10.1038/s42255-020-0181-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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