6KDB

Crystal structure of human DNMT3B-DNMT3L in complex with DNA containing CpGpT site

Summary for 6KDB

• Entry DOI: 10.2210/pdb6kdb/pdb
• Descriptor: DNA (cytosine-5)-methyltransferase 3B, DNA (cytosine-5)-methyltransferase 3-like, DNA (25-MER), ... (5 entities in total)
• Functional Keywords: dnmt3b, dna methyltransferase, complex, transferase, transferase-dna complex, transferase/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 128850.72

Authors

Lin, C.-C.,Chen, Y.-P.,Yang, W.-Z.,Shen, C.-K.,Yuan, H.S. (deposition date: 2019-07-01, release date: 2020-02-19, Last modification date: 2023-11-22)

• Primary citation: Lin, C.C.,Chen, Y.P.,Yang, W.Z.,Shen, J.C.K.,Yuan, H.S.; Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B.; Nucleic Acids Res., 48:3949-3961, 2020; PubMed: 32083663; DOI: 10.1093/nar/gkaa111

Experimental method

X-RAY DIFFRACTION (2.862 Å)