6V6Q

Crystal Structure of Monophosphorylated FGF Receptor 2 isoform IIIb with PTR657

Summary for 6V6Q

Entry DOI	10.2210/pdb6v6q/pdb
Descriptor	Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	fibroblast growth factor receptor 2, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	187982.49
Authors	Lin, C.-C.,Wieteska, L.,Poncet-Montange, G.,Suen, K.M.,Arold, S.T.,Ahmed, Z.,Ladbury, J.E. (deposition date: 2019-12-05, release date: 2020-11-11, Last modification date: 2024-11-20)
Primary citation	Lin, C.C.,Wieteska, L.,Poncet-Montange, G.,Suen, K.M.,Arold, S.T.,Ahmed, Z.,Ladbury, J.E. The combined action of the intracellular regions regulates FGFR2 kinase activity Commun Biol, 6:728-, 2023 Cited by DOI: 10.1038/s42003-023-05112-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.46 Å)

Structure validation