6V6Q

Crystal Structure of Monophosphorylated FGF Receptor 2 isoform IIIb with PTR657

Summary for 6V6Q

• Entry DOI: 10.2210/pdb6v6q/pdb
• Descriptor: Fibroblast growth factor receptor 2, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: fibroblast growth factor receptor 2, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 187982.49

Authors

Lin, C.-C.,Wieteska, L.,Poncet-Montange, G.,Suen, K.M.,Arold, S.T.,Ahmed, Z.,Ladbury, J.E. (deposition date: 2019-12-05, release date: 2020-11-11, Last modification date: 2023-11-15)

• Primary citation: Lin, C.C.,Wieteska, L.,Poncet-Montange, G.,Suen, K.M.,Arold, S.T.,Ahmed, Z.,Ladbury, J.E.; The combined action of the intracellular regions regulates FGFR2 kinase activity; Commun Biol, 6:728-, 2023; DOI: 10.1038/s42003-023-05112-6

Experimental method

X-RAY DIFFRACTION (2.46 Å)