4QYO
| Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 14-22 | Descriptor: | Fv fragment(mAb6D8) heavy chain, Fv fragment(mAb6D8) light chain, Merozoite surface antigen 2 | Authors: | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | Deposit date: | 2014-07-24 | Release date: | 2015-06-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.208 Å) | Cite: | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate. Sci Rep, 5, 2015
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4R3S
| Crystal Structure of anti-MSP2 Fv fragment (mAb6D8)in complex with MSP2 11-23 | Descriptor: | FV FRAGMENT(MAB6D8) HEAVY CHAIN, FV FRAGMENT(MAB6D8) LIGHT CHAIN, Merozoite surface protein | Authors: | Morales, R.A.V, MacRaild, C.A, Seow, J, Bankala, K, Drinkwater, N, McGowan, S, Rouet, R, Christ, D, Anders, R.F, Norton, R.S. | Deposit date: | 2014-08-18 | Release date: | 2015-06-03 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate Sci Rep, 5, 2015
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6D9I
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5V3P
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7RT9
| Crystal structures of human PYY and NPY | Descriptor: | 4A3B2-A Fab heavy chain, 4A3B2-A Fab light chain, GLYCEROL, ... | Authors: | Langley, D.B, Christ, D. | Deposit date: | 2021-08-12 | Release date: | 2022-03-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY). Neuropeptides, 92, 2022
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7RTA
| Crystal structures of human PYY and NPY | Descriptor: | 4A3B2-B Fab heavy chain, 4A3B2-B Fab light chain, Neuropeptide Y, ... | Authors: | Langley, D.B, Christ, D. | Deposit date: | 2021-08-12 | Release date: | 2022-03-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY). Neuropeptides, 92, 2022
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5V3B
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5TBD
| Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | Descriptor: | Fv fragment (mAb4D1) heavy chain, Merozoite surface protein 2 | Authors: | Seow, J, Morales, R.A.V, MacRaild, C.A, Bankala, K, Drinkwater, N, Dingjan, T, Jaipuria, G, Wilde, K, Anders, R.F, Atreya, H.S, Christ, D, McGowan, S, Norton, R.S. | Deposit date: | 2016-09-12 | Release date: | 2017-02-15 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and Characterisation of a Key Epitope in the Conserved C-Terminal Domain of the Malaria Vaccine Candidate MSP2. J. Mol. Biol., 429, 2017
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5VJO
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5VJQ
| Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I) | Descriptor: | CHLORIDE ION, GLYCEROL, HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, ... | Authors: | Langley, D.B, Christ, D. | Deposit date: | 2017-04-19 | Release date: | 2018-04-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination. Science, 360, 2018
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3BPV
| Crystal Structure of MarR | Descriptor: | Transcriptional regulator | Authors: | Saridakis, V, Shahinas, D, Xu, X, Christendat, D. | Deposit date: | 2007-12-19 | Release date: | 2008-05-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum. J.Mol.Biol., 377, 2008
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1LXN
| X-RAY STRUCTURE OF MTH1187 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET TT272 | Descriptor: | HYPOTHETICAL PROTEIN MTH1187, SULFATE ION | Authors: | Tao, X, Khayat, R, Christendat, D, Savchenko, A, Xu, X, Edwards, A, Arrowsmith, C.H, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-06-05 | Release date: | 2003-07-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structures of MTH1187 and its Yeast Ortholog YBL001C Proteins, 52, 2003
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6U60
| Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD and L-tyrosine | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Prephenate dehydrogenase, ... | Authors: | Shabalin, I.G, Hou, J, Kutner, J, Grimshaw, S, Christendat, D, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-08-28 | Release date: | 2019-09-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
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3BPX
| Crystal Structure of MarR | Descriptor: | 2-HYDROXYBENZOIC ACID, SODIUM ION, Transcriptional regulator | Authors: | Saridakis, V, Shahinas, D, Xu, X, Christendat, D. | Deposit date: | 2007-12-19 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum. J.Mol.Biol., 377, 2008
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5HMQ
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2AS0
| Crystal Structure of PH1915 (APC 5817): A Hypothetical RNA Methyltransferase | Descriptor: | hypothetical protein PH1915 | Authors: | Sun, W, Xu, X, Pavlova, M, Edwards, A.M, Joachimiak, A, Savchenko, A, Christendat, D, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-08-22 | Release date: | 2005-09-20 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii. Protein Sci., 14, 2005
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3GGO
| Crystal structure of prephenate dehydrogenase from A. aeolicus with HPP and NADH | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 3-(4-HYDROXY-PHENYL)PYRUVIC ACID, Prephenate dehydrogenase | Authors: | Sun, W, Shahinas, D, Christendat, D. | Deposit date: | 2009-03-01 | Release date: | 2009-03-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition. J.Biol.Chem., 284, 2009
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3GGP
| Crystal structure of prephenate dehydrogenase from A. aeolicus in complex with hydroxyphenyl propionate and NAD+ | Descriptor: | CHLORIDE ION, HYDROXYPHENYL PROPIONIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Sun, W, Shahinas, D, Kimber, M.S, Christendat, D. | Deposit date: | 2009-03-01 | Release date: | 2009-03-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The Crystal Structure of Aquifex aeolicus Prephenate Dehydrogenase Reveals the Mode of Tyrosine Inhibition. J.Biol.Chem., 284, 2009
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3GGG
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1KUU
| CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD | Descriptor: | conserved protein | Authors: | Saridakis, V, Christendat, D, Thygesen, A, Arrowsmith, C.H, Edwards, A.M, Pai, E.F. | Deposit date: | 2002-01-22 | Release date: | 2002-05-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | CRYSTAL STRUCTURE OF METHANOBACTERIUM THERMOAUTOTROPHICUM CONSERVED PROTEIN MTH1020 REVEALS AN NTN-HYDROLASE FOLD PROTEINS: STRUCT.,FUNCT.,GENET., 48, 2002
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1NOG
| Crystal Structure of Conserved Protein 0546 from Thermoplasma Acidophilum | Descriptor: | conserved hypothetical protein TA0546 | Authors: | Saridakis, V, Sanishvili, R, Iakounine, A, Xu, X, Pennycooke, M, Gu, J, Joachimiak, A, Arrowsmith, C.H, Edwards, A.M, Christendat, D, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-01-16 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase. J.Biol.Chem., 279, 2004
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5TED
| Effector binding domain of QuiR in complex with shikimate | Descriptor: | (3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC ACID, His Tag peptide, Lmo0488 protein | Authors: | Prezioso, S.M, Christendat, D. | Deposit date: | 2016-09-21 | Release date: | 2017-10-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.889 Å) | Cite: | Shikimate Induced Transcriptional Activation of Protocatechuate Biosynthesis Genes by QuiR, a LysR-Type Transcriptional Regulator, in Listeria monocytogenes. J. Mol. Biol., 430, 2018
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5V0S
| Crystal structure of the ACT domain of prephenate dehydrogenase tyrA from Bacillus anthracis | Descriptor: | CALCIUM ION, Prephenate dehydrogenase, SULFATE ION | Authors: | Shabalin, I.G, Hou, J, Cymborowski, M.T, Otwinowski, Z, Kwon, K, Christendat, D, Gritsunov, A, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-28 | Release date: | 2017-03-08 | Last modified: | 2022-03-23 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
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7MQV
| Crystal structure of truncated (ACT domain removed) prephenate dehydrogenase tyrA from Bacillus anthracis in complex with NAD | Descriptor: | CHLORIDE ION, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Shabalin, I.G, Gritsunov, A, Gabryelska, A, Czub, M.P, Grabowski, M, Cooper, D.R, Christendat, D, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2021-05-06 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The crystal structure of Bacillus anthracis prephenate dehydrogenase identified an ACT regulatory domain and a novel mode of metabolic regulation for proteins within the prephenate dehydrogenase family of enzyme to be published
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5UYY
| Crystal structure of prephenate dehydrogenase tyrA from Bacillus anthracis in complex with L-tyrosine | Descriptor: | Prephenate dehydrogenase, TYROSINE | Authors: | Shabalin, I.G, Hou, J, Cymborowski, M.T, Kwon, K, Christendat, D, Gritsunov, A.O, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-02-24 | Release date: | 2017-03-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and biochemical analysis of Bacillus anthracis prephenate dehydrogenase reveals an unusual mode of inhibition by tyrosine via the ACT domain. Febs J., 287, 2020
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