5VJQ

Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I)

Summary for 5VJQ

• Entry DOI: 10.2210/pdb5vjq/pdb
• Related: 5VJO
• Descriptor: HyHEL10 heavy chain Fab fragment carrying three mutations; I29F, S52T, Y53F, HyHEL10 light chain Fab fragment, Lysozyme, ... (6 entities in total)
• Functional Keywords: lysozyme, hydrolase, hydrolase-immune system complex, hydrolase/immune system
• Biological source: Mus musculus; More
• Total number of polymer chains: 12
• Total formula weight: 244885.18

Authors

Langley, D.B.,Christ, D. (deposition date: 2017-04-19, release date: 2018-04-11, Last modification date: 2023-10-04)

• Primary citation: Burnett, D.L.,Langley, D.B.,Schofield, P.,Hermes, J.R.,Chan, T.D.,Jackson, J.,Bourne, K.,Reed, J.H.,Patterson, K.,Porebski, B.T.,Brink, R.,Christ, D.,Goodnow, C.C.; Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination.; Science, 360:223-226, 2018; PubMed: 29650674; DOI: 10.1126/science.aao3859

Experimental method

X-RAY DIFFRACTION (1.9 Å)