6R5L
| Fragment AZ-006 binding at the p53pT387/14-3-3 sigma interface | Descriptor: | 14-3-3 protein sigma, 4-[[(2~{S})-1-azanylpropan-2-yl]amino]-6-(sulfanylmethyl)-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... | Authors: | Genet, S, Wolter, M, Guillory, X, Somsen, B, Leysen, S, Castaldi, P, Ottmann, C. | Deposit date: | 2019-03-25 | Release date: | 2020-06-17 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.884 Å) | Cite: | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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6R7E
| N-terminally reversed variant of FimA E. coli with alanine insertion at position 20 | Descriptor: | FimA, SULFATE ION | Authors: | Zyla, D, Echeverria, B, Glockshuber, R. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
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2FYB
| Crystal structure of the catalytic domain of the human beta1,4-galactosyltransferase mutant M339H in complex with Mn and UDP-galactose in open conformation | Descriptor: | Beta-1,4-galactosyltransferase 1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE | Authors: | Ramakrishnan, B, Ramasamy, V, Qasba, P.K. | Deposit date: | 2006-02-07 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Snapshots of beta-1,4-Galactosyltransferase-I Along the Kinetic Pathway. J.Mol.Biol., 357, 2006
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6XI1
| Crystal structure of tetra-tandem repeat in extending RTX adhesin from Aeromonas hydrophila | Descriptor: | CALCIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Ye, Q, Vance, T.D.R, Conroy, B, Davies, P.L. | Deposit date: | 2020-06-19 | Release date: | 2020-10-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Essential role of calcium in extending RTX adhesins to their target. J Struct Biol X, 4, 2020
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6XJ9
| Structure of PfGH50B | Descriptor: | 1,2-ETHANEDIOL, Agarase | Authors: | Pluvinage, B, Boraston, A.B. | Deposit date: | 2020-06-23 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of PfGH50B, an agarase from the marine bacterium Pseudoalteromonas fuliginea PS47 Acta Crystallogr.,Sect.F, 76, 2020
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2FWL
| The cytochrome c552/CuA complex from Thermus thermophilus | Descriptor: | Cytochrome c oxidase subunit II, Cytochrome c-552, DINUCLEAR COPPER ION, ... | Authors: | Muresanu, L, Pristovsek, P, Loehr, F, Maneg, O, Mukrasch, M.D, Rueterjans, H, Ludwig, B, Luecke, C. | Deposit date: | 2006-02-02 | Release date: | 2006-03-28 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | The electron transfer complex between cytochrome c552 and the CuA domain of the Thermus thermophilus ba3 oxidase - a combined NMR and computational approach J.Biol.Chem., 281, 2006
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6RBM
| TETR(D) E147A MUTANT IN COMPLEX WITH MINOCYCLINE AND MAGNESIUM | Descriptor: | (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | Deposit date: | 2019-04-11 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868, 2020
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2FVH
| Crystal Structure of Rv1848, a Urease Gamma Subunit UreA (Urea amidohydrolase), from Mycobacterium Tuberculosis | Descriptor: | Urease gamma subunit | Authors: | Bursey, E.H, Yu, M, TB Structural Genomics Consortium (TBSGC), Lekin, T, Rupp, B, Kim, C.Y, Rho, B.S, Terwilliger, T.C. | Deposit date: | 2006-01-30 | Release date: | 2006-02-07 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of Rv1848, a Urease Gamma Subunit UreA (Urea amidohydrolase), from Mycobacterium Tuberculosis To be Published
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6XE0
| Cryo-EM structure of NusG-CTD bound to 70S ribosome (30S: NusG-CTD fragment) | Descriptor: | 16s rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Washburn, R, Zuber, P, Sun, M, Hashem, Y, Shen, B, Li, W, Harvey, S, Acosta-Reyes, F.J, Knauer, S.H, Frank, J, Gottesman, M.E. | Deposit date: | 2020-06-11 | Release date: | 2020-07-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (6.8 Å) | Cite: | Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience, 23, 2020
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4S2L
| Crystal Structure of OXA-163 beta-lactamase | Descriptor: | Beta-lactamase, SODIUM ION | Authors: | Stojanoski, V, Liya, H, Palzkill, T.G, Prasad, B, Sankaran, B. | Deposit date: | 2015-01-21 | Release date: | 2015-07-22 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Basis for Different Substrate Profiles of Two Closely Related Class D beta-Lactamases and Their Inhibition by Halogens. Biochemistry, 54, 2015
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6R74
| N-terminally reversed variant of FimA E. coli | Descriptor: | SULFATE ION, Type-1 fimbrial protein, A chain | Authors: | Zyla, D, Echeverria, B, Glockshuber, R. | Deposit date: | 2019-03-28 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Donor strand sequence, rather than donor strand orientation, determines the stability and non-equilibrium folding of the type 1 pilus subunit FimA. J.Biol.Chem., 295, 2020
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2FXT
| Crystal Structure of Yeast Tim44 | Descriptor: | Import inner membrane translocase subunit TIM44 | Authors: | Josyula, R, Sha, B. | Deposit date: | 2006-02-06 | Release date: | 2007-02-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of Yeast Mitochondrial Peripheral Membrane Protein Tim44p C-terminal Domain. J.Mol.Biol., 359, 2006
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6R7Q
| Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | Deposit date: | 2019-03-29 | Release date: | 2019-07-10 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
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6X9H
| Molecular mechanism and structural basis of small-molecule modulation of acid-sensing ion channel 1 (ASIC1) | Descriptor: | 2-[4-(3,4-dimethoxyphenoxy)phenyl]-1H-benzimidazole-6-carboximidamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Liu, Y, Ma, J, DesJarlais, R.L, Hagan, R, Rech, J, Lin, D, Liu, C, Miller, R, Schoellerman, J, Luo, J, Letavic, M, Grasberger, B, Maher, M. | Deposit date: | 2020-06-02 | Release date: | 2020-12-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.01 Å) | Cite: | Molecular mechanism and structural basis of small-molecule modulation of the gating of acid-sensing ion channel 1. Commun Biol, 4, 2021
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6RBD
| State 1 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles | Descriptor: | 20S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. | Deposit date: | 2019-04-10 | Release date: | 2019-06-26 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
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6XR3
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6RCR
| TETR(D) H100A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM | Descriptor: | (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ... | Authors: | Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B. | Deposit date: | 2019-04-11 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. Biochim Biophys Acta Proteins Proteom, 1868, 2020
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6XVC
| CRYSTAL STRUCTURE OF BRD4-BD1 WITH COMPOUND 1 | Descriptor: | (4~{R})-4-[(1~{R})-1-[7-(3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)quinolin-5-yl]oxyethyl]pyrrolidin-2-one, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | Authors: | Bader, G, Kessler, D, Wolkerstorfer, B. | Deposit date: | 2020-01-21 | Release date: | 2020-07-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.098 Å) | Cite: | PI by NMR: Probing CH-pi Interactions in Protein-Ligand Complexes by NMR Spectroscopy. Angew.Chem.Int.Ed.Engl., 59, 2020
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6XVI
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6XWS
| Crystal Structure of Drosophila CAL1 1-160 bound to CENP-A/H4 | Descriptor: | Chromosome alignment defect 1,Chromosome alignment defect 1, Histone H3-like centromeric protein cid, Histone H4 | Authors: | Jeyaprakash, A.A, Medina-Pritchard, B, Lazou, V, Zou, J, Byron, O, Abad, M.A, Rappsilber, J, Heun, P. | Deposit date: | 2020-01-24 | Release date: | 2020-04-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (4.36 Å) | Cite: | Structural basis for centromere maintenance by Drosophila CENP-A chaperone CAL1. Embo J., 39, 2020
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6R82
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6RB2
| Structure of the (SR)Ca2+-ATPase mutant E340A in the Ca2-E1-CaAMPPCP form | Descriptor: | CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, POTASSIUM ION, ... | Authors: | Clausen, J.D, Montigny, C, Lenoir, G, Arnou, B, Jaxel, C, Moller, J.V, Nissen, P, Andersen, J.P, Le Maire, M, Bublitz, M. | Deposit date: | 2019-04-09 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.20001125 Å) | Cite: | The SERCA residue Glu340 mediates interdomain communication that guides Ca 2+ transport. Proc.Natl.Acad.Sci.USA, 117, 2020
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6RBE
| State 2 of yeast Tsr1-TAP Rps20-Deltaloop pre-40S particles | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Shayan, R, Mitterer, V, Ferreira-Cerca, S, Murat, G, Enne, T, Rinaldi, D, Weigl, S, Omanic, H, Gleizes, P.E, Kressler, D, Pertschy, B, Plisson-Chastang, C. | Deposit date: | 2019-04-10 | Release date: | 2019-06-26 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism. Nat Commun, 10, 2019
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6XSZ
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6XUC
| Structure of coproheme decarboxylase from Corynebacterium diphteriae in complex with coproheme | Descriptor: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Chlorite dismutase | Authors: | Michlits, H, Lier, B, Pfanzagl, V, Djinovic-Carugo, K, Furtmueller, P.G, Oostenbrink, C, Obinger, C, Hofbauer, S. | Deposit date: | 2020-01-17 | Release date: | 2020-04-22 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.8702 Å) | Cite: | Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation. Acs Catalysis, 10, 2020
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