6XR3

X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A

Summary for 6XR3

• Entry DOI: 10.2210/pdb6xr3/pdb
• Related: 6W63 6WNP
• Descriptor: 3C-like proteinase, N-[(2S)-1-({(1S,2S)-1-(1,3-benzothiazol-2-yl)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide (3 entities in total)
• Functional Keywords: inhibitor, main protease, mpro, 3c-like, 3clpro, sars-cov-2, covid-19, nsp5, structural genomics, center for structural genomics of infectious diseases, csgid, hydrolase
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• Total number of polymer chains: 1
• Total formula weight: 34403.24

Authors

Anson, B.,Ghosh, A.K.,Mesecar, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2020-07-10, release date: 2020-08-19, Last modification date: 2023-10-18)

• Primary citation: Anson, B.,Ghosh, A.K.,Mesecar, A.; X-ray Structure of SARS-CoV-2 main protease bound to GRL-024-20 at 1.45 A; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)