6N44
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6n44 by Molmil](/molmil-images/mine/6n44) | |
5KBF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kbf by Molmil](/molmil-images/mine/5kbf) | cAMP bound PfPKA-R (141-441) | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit, putative | Authors: | Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. | Deposit date: | 2016-06-03 | Release date: | 2016-10-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
|
|
5K8S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5k8s by Molmil](/molmil-images/mine/5k8s) | cAMP bound PfPKA-R (297-441) | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, CAMP-dependent protein kinase regulatory subunit | Authors: | Littler, D.R, Gilson, P.R, Crabb, B.S, Rossjohn, J.J. | Deposit date: | 2016-05-31 | Release date: | 2016-10-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Disrupting the Allosteric Interaction between the Plasmodium falciparum cAMP-dependent Kinase and Its Regulatory Subunit. J. Biol. Chem., 291, 2016
|
|
3TOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3toa by Molmil](/molmil-images/mine/3toa) | Human MOF crystal structure with active site lysine partially acetylated | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
|
|
3TO6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3to6 by Molmil](/molmil-images/mine/3to6) | |
3TOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3tob by Molmil](/molmil-images/mine/3tob) | |
3TO9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3to9 by Molmil](/molmil-images/mine/3to9) | Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated | Descriptor: | 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2012-01-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
|
|
3TO7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3to7 by Molmil](/molmil-images/mine/3to7) | Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated | Descriptor: | CACODYLIC ACID, COENZYME A, GLYCEROL, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
|
|
6XQA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xqa by Molmil](/molmil-images/mine/6xqa) | Crystal Structure of HLA A*2402 in complex with TYQWVLKNL, an 9-mer epitope from Influenza B virus | Descriptor: | Beta-2-microglobulin, MAGNESIUM ION, MHC class I antigen, ... | Authors: | Nguyen, A.T, Szeto, C, Gras, S. | Deposit date: | 2020-07-09 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | CD8 + T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nat Commun, 12, 2021
|
|
5N29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n29 by Molmil](/molmil-images/mine/5n29) | |
6PBH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pbh by Molmil](/molmil-images/mine/6pbh) | |
5EXH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5exh by Molmil](/molmil-images/mine/5exh) | |
5TPX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5tpx by Molmil](/molmil-images/mine/5tpx) | Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound | Descriptor: | (1S,2S)-N~1~,N~1~-dimethyl-N~2~-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-1-phenylpropane-1,2-diamine, CHLORIDE ION, Histone acetyltransferase GCN5, ... | Authors: | Lin, Y.H, Hou, C.F.D, MOUSTAKIM, M, DIXON, D.J, Loppnau, P, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, BRENNAN, P.E, Walker, J.R, Structural Genomics Consortium (SGC) | Deposit date: | 2016-10-21 | Release date: | 2017-01-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of a PCAF Bromodomain Chemical Probe. Angew. Chem. Int. Ed. Engl., 56, 2017
|
|
8GSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8gss by Molmil](/molmil-images/mine/8gss) | Human glutathione S-transferase P1-1, complex with glutathione | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE P1-1, ... | Authors: | Oakley, A, Parker, M. | Deposit date: | 1997-08-14 | Release date: | 1998-09-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution. J.Mol.Biol., 274, 1997
|
|
6NF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nf7 by Molmil](/molmil-images/mine/6nf7) | Crystal Structure of RT1.Aa-Bu31-10 | Descriptor: | Beta-2-microglobulin, Bu31-10 peptide, RT1A.a | Authors: | Gras, S. | Deposit date: | 2018-12-19 | Release date: | 2019-12-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Cross-Reactive Donor-Specific CD8+Tregs Efficiently Prevent Transplant Rejection. Cell Rep, 29, 2019
|
|
6UKT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ukt by Molmil](/molmil-images/mine/6ukt) | Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, NB8117, ... | Authors: | Mou, T.C, Zhang, K, Johnston, J.D, Chiu, W, Sprang, S.R. | Deposit date: | 2019-10-05 | Release date: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11, 2020
|
|
5N1Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5n1y by Molmil](/molmil-images/mine/5n1y) | HLA-A02 carrying MVWGPDPLYV | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | Deposit date: | 2017-02-06 | Release date: | 2017-02-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J. Clin. Invest., 126, 2016
|
|
7LTZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ltz by Molmil](/molmil-images/mine/7ltz) | Bruton's tyrosine kinase in complex with compound 51 | Descriptor: | 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... | Authors: | Metrick, C.M, Marcotte, D.J. | Deposit date: | 2021-02-20 | Release date: | 2022-01-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 65, 2022
|
|
7LTY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7lty by Molmil](/molmil-images/mine/7lty) | Bruton's tyrosine kinase in complex with compound 23 | Descriptor: | DIMETHYL SULFOXIDE, Isoform BTK-C of Tyrosine-protein kinase BTK, ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide | Authors: | Metrick, C.M, Marcotte, D.J. | Deposit date: | 2021-02-20 | Release date: | 2022-01-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 65, 2022
|
|
9GSS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9gss by Molmil](/molmil-images/mine/9gss) | HUMAN GLUTATHIONE S-TRANSFERASE P1-1, COMPLEX WITH S-HEXYL GLUTATHIONE | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, S-HEXYLGLUTATHIONE, ... | Authors: | Oakley, A, Parker, M. | Deposit date: | 1997-08-14 | Release date: | 1998-09-16 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | The structures of human glutathione transferase P1-1 in complex with glutathione and various inhibitors at high resolution. J.Mol.Biol., 274, 1997
|
|
6PYV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyv by Molmil](/molmil-images/mine/6pyv) | Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-2703 alpha chain, ... | Authors: | Gras, S. | Deposit date: | 2019-07-31 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. J.Biol.Chem., 294, 2019
|
|
6PYJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyj by Molmil](/molmil-images/mine/6pyj) | Crystal Structure of HLA-B*2705 in complex with LRN, a self-peptide | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | Authors: | Gras, S. | Deposit date: | 2019-07-30 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. J.Biol.Chem., 294, 2019
|
|
6PYW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyw by Molmil](/molmil-images/mine/6pyw) | Crystal Structure of HLA-B*2705-W60A in complex with LRN, a self-peptide | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | Authors: | Gras, S. | Deposit date: | 2019-07-31 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. J.Biol.Chem., 294, 2019
|
|
6PYL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pyl by Molmil](/molmil-images/mine/6pyl) | Crystal Structure of HLA-B*2703 in complex with KK10, an HIV peptide | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27:03 alpha chain, ... | Authors: | Gras, S. | Deposit date: | 2019-07-30 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. J.Biol.Chem., 294, 2019
|
|
6PZ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6pz5 by Molmil](/molmil-images/mine/6pz5) | Crystal Structure of HLA-B*2703 in complex with LRN, a self-peptide | Descriptor: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B*27:03 alpha chain, ... | Authors: | Gras, S. | Deposit date: | 2019-07-31 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation. J.Biol.Chem., 294, 2019
|
|