6UKT

Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex

Summary for 6UKT

• Entry DOI: 10.2210/pdb6ukt/pdb
• EMDB information: 20812
• Descriptor: Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans), Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, ... (6 entities in total)
• Functional Keywords: ric-8a, g protein, gef, signaling protein
• Biological source: Rattus norvegicus (Rat); More
• Total number of polymer chains: 6
• Total formula weight: 150597.49

Authors

Mou, T.C.,Zhang, K.,Johnston, J.D.,Chiu, W.,Sprang, S.R. (deposition date: 2019-10-05, release date: 2020-03-11)

• Primary citation: McClelland, L.J.,Zhang, K.,Mou, T.C.,Johnston, J.,Yates-Hansen, C.,Li, S.,Thomas, C.J.,Doukov, T.I.,Triest, S.,Wohlkonig, A.,Tall, G.G.,Steyaert, J.,Chiu, W.,Sprang, S.R.; Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1.; Nat Commun, 11:1077-1077, 2020; PubMed: 32103024; DOI: 10.1038/s41467-020-14943-4

Experimental method

ELECTRON MICROSCOPY (3.87 Å)