6UKT
Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) | polymer | 492 | 55836.9 | 1 | UniProt (B1H241) Pfam (PF10165) In PDB | Rattus norvegicus (Rat) | Ric8a protein,Synembryn-A |
| 2 | B | Guanine nucleotide-binding protein G(i) subunit alpha-1 | polymer | 323 | 37015.2 | 1 | UniProt (P10824) Pfam (PF00503) In PDB | Rattus norvegicus (Rat) | Adenylate cyclase-inhibiting G alpha protein |
| 3 | C | NB8109 | polymer | 124 | 13609.9 | 1 | Lama glama (llama) | ||
| 4 | D | NB8117 | polymer | 134 | 14894.4 | 1 | Lama glama (llama) | ||
| 5 | E | NB8119 | polymer | 131 | 14247.6 | 1 | Lama glama (llama) | ||
| 6 | F | NB9156 | polymer | 134 | 14993.4 | 1 | Lama glama (llama) |
Sequence modifications
A: 1 - 491 (UniProt: B1H241)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Phe 232 | Tyr 232 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 150597.5 | |
| All* | Total formula weight | 150597.5 |
