7X1Y
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![BU of 7x1y by Molmil](/molmil-images/mine/7x1y) | Structure of the phosphorylation-site double mutant S431A/T432A of the KaiC circadian clock protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | Authors: | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | Deposit date: | 2022-02-25 | Release date: | 2023-04-26 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex Nat Commun, 14, 2023
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7X1Z
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![BU of 7x1z by Molmil](/molmil-images/mine/7x1z) | Structure of the phosphorylation-site double mutant S431E/T432E of the KaiC circadian clock protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock oscillator protein KaiC, MAGNESIUM ION | Authors: | Han, X, Zhang, D.L, Hong, L, Yu, D.Q, Wu, Z.L, Yang, T, Rust, M.J, Tu, Y.H, Ouyang, Q. | Deposit date: | 2022-02-25 | Release date: | 2023-04-19 | Last modified: | 2023-11-08 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Determining subunit-subunit interaction from statistics of cryo-EM images: observation of nearest-neighbor coupling in a circadian clock protein complex Nat Commun, 14, 2023
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6IV3
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![BU of 6iv3 by Molmil](/molmil-images/mine/6iv3) | |
6IVM
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![BU of 6ivm by Molmil](/molmil-images/mine/6ivm) | Crystal structure of a membrane protein P143A | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | Deposit date: | 2018-12-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
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6IVO
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![BU of 6ivo by Molmil](/molmil-images/mine/6ivo) | Crystal structure of a membrane protein P208A | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | Deposit date: | 2018-12-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
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6IVQ
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![BU of 6ivq by Molmil](/molmil-images/mine/6ivq) | Crystal structure of a membrane protein S19A | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | Deposit date: | 2018-12-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
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6IV4
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![BU of 6iv4 by Molmil](/molmil-images/mine/6iv4) | |
6IVR
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![BU of 6ivr by Molmil](/molmil-images/mine/6ivr) | Crystal structure of a membrane protein W16A | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | Deposit date: | 2018-12-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
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6IV0
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![BU of 6iv0 by Molmil](/molmil-images/mine/6iv0) | |
6IVK
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![BU of 6ivk by Molmil](/molmil-images/mine/6ivk) | Crystal structure of a membrane protein G175A | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | Authors: | Kittredge, A, Fukuda, F, Zhang, Y, Yang, T. | Deposit date: | 2018-12-04 | Release date: | 2019-11-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Dual Ca2+-dependent gates in human Bestrophin1 underlie disease-causing mechanisms of gain-of-function mutations. Commun Biol, 2, 2019
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6IVW
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![BU of 6ivw by Molmil](/molmil-images/mine/6ivw) | |
6IV1
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8ECY
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![BU of 8ecy by Molmil](/molmil-images/mine/8ecy) | cryoEM structure of bovine bestrophin-2 and glutamine synthetase complex | Descriptor: | Bestrophin, CALCIUM ION, CHLORIDE ION, ... | Authors: | Owji, A.P, Kittredge, A.K, Yang, T. | Deposit date: | 2022-09-02 | Release date: | 2022-11-02 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2 Å) | Cite: | Bestrophin-2 and glutamine synthetase form a complex for glutamate release. Nature, 611, 2022
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1ZVM
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![BU of 1zvm by Molmil](/molmil-images/mine/1zvm) | Crystal structure of human CD38: cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase | Descriptor: | ADP-ribosyl cyclase 1, SULFATE ION | Authors: | Shi, W, Yang, T, Almo, S.C, Schramm, V.L, Sauve, A. | Deposit date: | 2005-06-02 | Release date: | 2006-06-06 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human CD38: Cyclic-ADP-ribosyl synthetase/NAD+ glycohydrolase To be Published
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7VPG
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![BU of 7vpg by Molmil](/molmil-images/mine/7vpg) | Crystal structure of the C-terminal tail of SARS-CoV-1 Orf6 complex with human nucleoporin pair Rae1-Nup98 | Descriptor: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | Authors: | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | Deposit date: | 2021-10-17 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
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7VPH
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![BU of 7vph by Molmil](/molmil-images/mine/7vph) | Crystal structure of the C-terminal tail of SARS-CoV-2 Orf6 complex with human nucleoporin pair Rae1-Nup98 | Descriptor: | Isoform 3 of Nuclear pore complex protein Nup98-Nup96, ORF6 protein, mRNA export factor | Authors: | Li, T, Guo, H, Yang, T, Wen, Y, Ji, X. | Deposit date: | 2021-10-17 | Release date: | 2022-01-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular Mechanism of SARS-CoVs Orf6 Targeting the Rae1-Nup98 Complex to Compete With mRNA Nuclear Export. Front Mol Biosci, 8, 2021
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5X87
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![BU of 5x87 by Molmil](/molmil-images/mine/5x87) | |
6JLF
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![BU of 6jlf by Molmil](/molmil-images/mine/6jlf) | |
7DCY
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![BU of 7dcy by Molmil](/molmil-images/mine/7dcy) | Apo form of Mycoplasma genitalium RNase R | Descriptor: | MAGNESIUM ION, Ribonuclease R | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | Deposit date: | 2020-10-27 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.972 Å) | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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7DIC
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![BU of 7dic by Molmil](/molmil-images/mine/7dic) | Mycoplasma genitalium RNase R in complex with single-stranded RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | Deposit date: | 2020-11-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.242 Å) | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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7DOL
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![BU of 7dol by Molmil](/molmil-images/mine/7dol) | Mycoplasma genitalium RNase R in complex with double-stranded RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), Ribonuclease R | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | Deposit date: | 2020-12-14 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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7DID
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![BU of 7did by Molmil](/molmil-images/mine/7did) | Mycoplasma genitalium RNase R in complex with ribose methylated single-stranded RNA | Descriptor: | MAGNESIUM ION, RNA (5'-R(*AP*AP*AP*A)-3'), Ribonuclease R | Authors: | Abula, A, Quan, X, Li, X, Yang, T, Li, T, Chen, Q, Ji, X. | Deposit date: | 2020-11-18 | Release date: | 2021-03-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular mechanism of RNase R substrate sensitivity for RNA ribose methylation. Nucleic Acids Res., 49, 2021
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7FGX
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![BU of 7fgx by Molmil](/molmil-images/mine/7fgx) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P39, NADPH and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 6-hexyl-5-phenyl-pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | Authors: | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | Deposit date: | 2021-07-28 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7FGY
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![BU of 7fgy by Molmil](/molmil-images/mine/7fgy) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with P40, NADPH and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(3-chlorophenyl)-6-[2-(3-phenoxypropoxy)ethyl]pyrimidine-2,4-diamine, Bifunctional dihydrofolate reductase-thymidylate synthase, ... | Authors: | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, J, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | Deposit date: | 2021-07-28 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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7FGW
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![BU of 7fgw by Molmil](/molmil-images/mine/7fgw) | Toxoplasma gondii dihydrofolate reductase thymidylate synthase (TgDHFR-TS) complexed with pyrimethamine, NADPH and dUMP | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, BENZAMIDINE, ... | Authors: | Vanichtanankul, J, Yoomuang, A, Taweechai, S, Saeyang, T, Yuvaniyama, Y, Tarnchompoo, B, Yuthavong, Y, Kamchonwongpaisan, S. | Deposit date: | 2021-07-28 | Release date: | 2022-06-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Insight into Effective Inhibitors' Binding to Toxoplasma gondii Dihydrofolate Reductase Thymidylate Synthase. Acs Chem.Biol., 17, 2022
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