8HU2
 
 | | Rattus Syntenin-1 PDZ domain with inhibitor | | Descriptor: | (2~{S})-2-(9~{H}-fluoren-9-ylmethoxycarbonylamino)-3-(4-oxidanylidene-5~{H}-pyrimidin-2-yl)propanoic acid, Syntenin-1 | | Authors: | Heo, Y, Lee, J, Yun, J.H, Lee, W. | | Deposit date: | 2022-12-22 | | Release date: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystal structure of STNPDZ with inhibitor at 1.60 Angstroms resolution.
To Be Published
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7FCI
 | | human NTCP in complex with YN69083 Fab | | Descriptor: | Fab Heavy chain, Fab Light chain, Sodium/bile acid cotransporter | | Authors: | Park, J.H, Iwamoto, M, Yun, J.H, Uchikubo-Kamo, T, Son, D, Jin, Z, Yoshida, H, Ohki, M, Ishimoto, N, Mizutani, K, Oshima, M, Muramatsu, M, Wakita, T, Shirouzu, M, Liu, K, Uemura, T, Nomura, N, Iwata, S, Watashi, K, Tame, J.R.H, Nishizawa, T, Lee, W, Park, S.Y. | | Deposit date: | 2021-07-14 | | Release date: | 2022-05-25 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structural insights into the HBV receptor and bile acid transporter NTCP.
Nature, 606, 2022
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7CYU
 | | Crystal structure of human BAF57 HMG domain | | Descriptor: | SULFATE ION, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | | Authors: | Heo, Y, Yun, J.H, Park, J.H, Lee, W. | | Deposit date: | 2020-09-04 | | Release date: | 2020-10-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Crystal structure of the HMG domain of human BAF57 and its interaction with four-way junction DNA.
Biochem.Biophys.Res.Commun., 533, 2020
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7C4P
 | | Crystal structure of DBD plasma treated zebrafish TRF2 myb-domain complexed with DNA | | Descriptor: | DNA (5'-D(*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), ... | | Authors: | Jin, Z, Park, J.H, Yun, J.H, Park, S.Y, Lee, W. | | Deposit date: | 2020-05-18 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.995 Å) | | Cite: | Crystal structure of DBD plasma treated zebrafish TRF2 myb-domain complexed with DNA
To Be Published
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7C4Q
 | | Crystal structure of DBD plasma treated zebrafish TRF2 myb-domain complexed with DNA | | Descriptor: | DNA (5'-D(*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*G)-3'), ... | | Authors: | Jin, Z, Park, J.H, Yun, J.H, Park, S.Y, Lee, W. | | Deposit date: | 2020-05-18 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of DBD plasma treated zebrafish TRF2 myb-domain complexed with DNA
To Be Published
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7C4R
 | | Crystal structure of hydrogen peroxide treated zebrafish TRF2 complexed with DNA | | Descriptor: | DNA (5'-D(*D*CP*DP*CP*DP*CP*DP*TP*DP*AP*DP*AP*DP*CP*DP*CP*DP*CP*DP*TP*DP*AP*DP*A)-3'), DNA (5'-D(*D*TP*DP*TP*DP*AP*DP*GP*DP*GP*DP*GP*DP*TP*DP*TP*DP*AP*DP*G)-3'), DNA (5'-D(*D*TP*DP*TP*DP*AP*DP*GP*DP*GP*DP*GP*DP*TP*DP*TP*DP*AP*DP*GP*DP*GP*DP*G)-3'), ... | | Authors: | Jin, Z, Park, J.H, Yun, J.H, Park, S.Y, Lee, W. | | Deposit date: | 2020-05-18 | | Release date: | 2021-05-26 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Crystal structure of hydrogen peroxide treated zebrafish TRF2 myb-domain complexed with DNA
To Be Published
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7DCK
 | | Crystal structure of phosphodiesterase tw9814 | | Descriptor: | Lactamase_B domain-containing protein, MANGANESE (II) ION | | Authors: | Heo, Y, Yun, J.H, Park, J.H, Park, S.B, Cha, S.S, Lee, W. | | Deposit date: | 2020-10-26 | | Release date: | 2021-10-27 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Structural and functional identification of the uncharacterized metallo-beta-lactamase superfamily protein TW9814 as a phosphodiesterase with unique metal coordination.
Acta Crystallogr D Struct Biol, 78, 2022
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5G1D
 | | The complex structure of syntenin-1 PDZ domain with c-terminal extension | | Descriptor: | SYNDECAN-4, SYNTENIN-1 | | Authors: | Lee, I, Kim, H, Yun, J.H, Lee, W. | | Deposit date: | 2016-03-25 | | Release date: | 2016-11-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
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5G1E
 | | The complex structure of syntenin-1 PDZ domain with c-terminal extension | | Descriptor: | SYNTENIN-1 | | Authors: | Lee, I, Kim, H, Yun, J.H, Lee, W. | | Deposit date: | 2016-03-25 | | Release date: | 2016-11-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | New Structural Insight of C-Terminal Region of Syntenin-1, Enhancing the Molecular Dimerization and Inhibitory Function Related on Syndecan-4 Signaling.
Sci.Rep., 6, 2016
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6JCF
 | | Cryogenic structure of HIV-1 Integrase catalytic core domain by synchrotron | | Descriptor: | CACODYLATE ION, Integrase | | Authors: | Park, J.H, Han, J, Kim, T.H, Yun, J.H, Lee, W. | | Deposit date: | 2019-01-28 | | Release date: | 2019-07-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.153 Å) | | Cite: | Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
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6JCG
 | | Room temperature structure of HIV-1 Integrase catalytic core domain by serial femtosecond crystallography. | | Descriptor: | CACODYLATE ION, Integrase | | Authors: | Park, J.H, Shi, Y, Han, J, Li, X, Kim, T.H, Yun, J.H. | | Deposit date: | 2019-01-28 | | Release date: | 2019-07-17 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Non-Cryogenic Structure and Dynamics of HIV-1 Integrase Catalytic Core Domain by X-ray Free-Electron Lasers.
Int J Mol Sci, 20, 2019
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2M17
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6LZP
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6AK2
 | | Crystal structure of the syntenin PDZ1 domain in complex with the peptide inhibitor KSL-128018 | | Descriptor: | Syntenin-1, peptide inhibitor KSL-128018 | | Authors: | Jin, Z.Y, Park, J.H, Yun, J.H, Haugaard-Kedstrom, L.M, Lee, W.T. | | Deposit date: | 2018-08-29 | | Release date: | 2019-09-04 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.868 Å) | | Cite: | A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma.
J.Med.Chem., 64, 2021
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2XHS
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7WJ5
 | | Cryo-EM structure of human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand binding specificity | | Descriptor: | Gai1 antibody (scfv16), Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Heo, Y.S, Yoon, E.J, Jeon, Y.E, Yun, J.-H, Ishimoto, N, Woo, H, Park, S.Y, Song, J, Lee, W.T. | | Deposit date: | 2022-01-05 | | Release date: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.72 Å) | | Cite: | Cryo-EM structure of the human somatostatin receptor 2 complex with its agonist somatostatin delineates the ligand-binding specificity.
Elife, 11, 2022
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7FDJ
 | | Engineered Hepatitis B virus core antigen with short linker T=4 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-07-16 | | Release date: | 2021-09-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7EP6
 | | Engineered Hepatitis B virus core antigen T=4 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-04-26 | | Release date: | 2021-09-01 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.86 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7EOY
 | | Engineered Hepatitis B virus core antigen T=3 | | Descriptor: | Capsid protein,Immunoglobulin G-binding protein A | | Authors: | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | Deposit date: | 2021-04-24 | | Release date: | 2021-09-01 | | Last modified: | 2022-02-16 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7X0C
 | | Crystal structure of phospholipase A1, AtDSEL | | Descriptor: | Phospholipase A1-IIgamma | | Authors: | Heo, Y, Lee, I, Moon, S, Lee, W. | | Deposit date: | 2022-02-21 | | Release date: | 2022-04-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.79909515 Å) | | Cite: | Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain.
Molecules, 27, 2022
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7X0D
 | | Crystal structure of phospholipase A1, CaPLA1 | | Descriptor: | Phospholipase A1, SULFATE ION | | Authors: | Heo, Y, Lee, I, Moon, S, Lee, W. | | Deposit date: | 2022-02-21 | | Release date: | 2022-04-13 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.39725161 Å) | | Cite: | Crystal Structures of the Plant Phospholipase A1 Proteins Reveal a Unique Dimerization Domain.
Molecules, 27, 2022
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7CFZ
 | | SH3 domain of NADPH oxidase activator 1 | | Descriptor: | NADPH oxidase activator 1 | | Authors: | Kim, M, Park, J.H, Attri, P, Lee, W. | | Deposit date: | 2020-06-29 | | Release date: | 2021-07-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.89 Å) | | Cite: | Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study.
Int.J.Biol.Macromol., 163, 2020
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6KZ7
 | | The crystal structure of BAF155 SWIRM domain and N-terminal elongated hSNF5 RPT1 domain complex: Chromatin remodeling complex | | Descriptor: | SWI/SNF complex subunit SMARCC1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | | Authors: | Lee, W, Han, J, Kim, I, Park, J.H, Joo, K, Lee, J, Suh, J.Y. | | Deposit date: | 2019-09-23 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | A Coil-to-Helix Transition Serves as a Binding Motif for hSNF5 and BAF155 Interaction.
Int J Mol Sci, 21, 2020
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7XBD
 | | Cryo-EM structure of human galanin receptor 2 | | Descriptor: | Galanin, Galanin receptor type 2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Ishimoto, N, Kita, S, Park, S.Y. | | Deposit date: | 2022-03-21 | | Release date: | 2022-07-13 | | Last modified: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.11 Å) | | Cite: | Structure of the human galanin receptor 2 bound to galanin and Gq reveals the basis of ligand specificity and how binding affects the G-protein interface.
Plos Biol., 20, 2022
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