Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8G91
DownloadVisualize
BU of 8g91 by Molmil
LaM domain of human LARP1 in complex with Rp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: GLYCEROL, Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
8G90
DownloadVisualize
BU of 8g90 by Molmil
LaM domain of human LARP1 in complex with Sp phosphorothioate isomer of AAAAA(SRA) RNA
Descriptor: Isoform 2 of La-related protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*(SRA))-3')
Authors:Kozlov, G, Jiang, J, Gehring, K.
Deposit date:2023-02-20
Release date:2024-04-17
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural insights into RNA binding by the LaM domain of LARP1
To Be Published
5VXQ
DownloadVisualize
BU of 5vxq by Molmil
X-Ray crystallography structure of the parallel stranded duplex formed by 5-rA5-dA-rA5
Descriptor: AMMONIUM ION, DNA/RNA (5'-R(*AP*AP*AP*AP*A)-D(P*A)-R(P*AP*AP*AP*AP*A)-3')
Authors:Xie, J, Chen, Y, Wei, X, Kozlov, G, Gehring, K.
Deposit date:2017-05-23
Release date:2017-08-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.002 Å)
Cite:Influence of nucleotide modifications at the C2' position on the Hoogsteen base-paired parallel-stranded duplex of poly(A) RNA.
Nucleic Acids Res., 45, 2017
9CIQ
DownloadVisualize
BU of 9ciq by Molmil
Crystal structure of human polymerase eta with incoming threofuranosyl thymine nucleoside triphosphate opposite template dA
Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A, Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-04
Release date:2024-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
9CI9
DownloadVisualize
BU of 9ci9 by Molmil
Crystal structure of human polymerase eta with incoming dCMPnPP nucleotide across threofuranosyl thymidine in DNA template at extension stage
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(TFT)P*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-02
Release date:2024-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
9CJ9
DownloadVisualize
BU of 9cj9 by Molmil
Crystal structure of human polymerase eta with incoming dAMPnPP nucleotide opposite O4-methyl threofuranosyl thymidine in DNA template at insertion stage
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(TFT)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-05
Release date:2024-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.98 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
9CHW
DownloadVisualize
BU of 9chw by Molmil
Crystal structure of human polymerase eta with incoming dAMPnPP nucleotide opposite threofuranosyl thymidine in DNA template
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(TFT)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-02
Release date:2024-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
9CIH
DownloadVisualize
BU of 9cih by Molmil
Crystal structure of human polymerase eta with incoming dCMPnPP nucleotide across O4-methyl threofuranosyl thymidine in DNA template at extension stage
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(A1A0L)P*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Tomar, R, Stone, M.P, Egli, M.
Deposit date:2024-07-03
Release date:2024-09-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
2LSC
DownloadVisualize
BU of 2lsc by Molmil
Solution structure of 2'F-ANA and ANA self-complementary duplex
Descriptor: DNA (5'-D(*(CFL)P*(GFL)P*(CFL)P*(GFL)P*(A5O)P*(A5O)P*(UAR)P*(UAR)P*(CFL)P*(GFL)P*(CFL)P*(GFL))-3')
Authors:Martin-Pintado, N, Yahyaee, M, Campos, R, Noronha, A, Wilds, C, Damha, M, Gonzalez, C.
Deposit date:2012-04-26
Release date:2012-07-18
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion.
Nucleic Acids Res., 40, 2012
2FIL
DownloadVisualize
BU of 2fil by Molmil
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT)
Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(TAF)P*AP*CP*GP*C)-3', COBALT HEXAMMINE(III)
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FIJ
DownloadVisualize
BU of 2fij by Molmil
Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-aU-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and Arabino-Uridine (aU)
Descriptor: 5'-D(*GP*CP*GP*TP*(A2M)P*(UAR)P*AP*CP*GP*C)-3', CHLORIDE ION, COBALT HEXAMMINE(III)
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.19 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FIH
DownloadVisualize
BU of 2fih by Molmil
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAA-aU-TCGCG, with Incorporated Arabino-Uridine (aU)
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*(UAR)P*TP*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2FII
DownloadVisualize
BU of 2fii by Molmil
Crystal Structure Analysis of the B-DNA Dodecamer CGCGAAT-aU-CGCG, with Incorporated Arabino-Uridin (aU)
Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*(UAR)P*CP*GP*CP*G)-3', MAGNESIUM ION
Authors:Egli, M, Li, F.
Deposit date:2005-12-29
Release date:2006-05-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H.
Biochemistry, 45, 2006
2GUN
DownloadVisualize
BU of 2gun by Molmil
RNA-Binding Affinities and Crystal Structure of Oligonucleotides containing Five-Atom Amide-Based Backbone Structures
Descriptor: 5'-D(*TP*TP*CP*(T2T)P*(CBR)P*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*AP*GP*AP*A)-3', COBALT (III) ION, ...
Authors:Pallan, P.S, Egli, M.
Deposit date:2006-05-01
Release date:2006-08-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:RNA-Binding Affinities and Crystal Structure of Oligonucleotides Containing Five-Atom Amide-Based Backbone Structures.
Biochemistry, 45, 2006
5DQI
DownloadVisualize
BU of 5dqi by Molmil
Crystal Structure of Human DNA Polymerase Eta Extending an O4-Ethylthymidine : dA Pair By Inserting dCTP Opposite dG
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*AP*C)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
2H9S
DownloadVisualize
BU of 2h9s by Molmil
Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System
Descriptor: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION
Authors:Egli, M, Pallan, P.S.
Deposit date:2006-06-11
Release date:2006-12-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system.
J.Am.Chem.Soc., 128, 2006
1HO6
DownloadVisualize
BU of 1ho6 by Molmil
CHIMERIC ARABINONUCLEIC ACID (ANA) HAIRPIN WITH ANA/RNA HYBRID STEM
Descriptor: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*G)-(P*(GAO)P*(UAR)P*(CAR)P*(CAR)-3')
Authors:Denisov, A.Y, Gehring, K.
Deposit date:2000-12-08
Release date:2001-11-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
1HOQ
DownloadVisualize
BU of 1hoq by Molmil
CHIMERIC RNA/DNA HAIRPIN
Descriptor: DNA/RNA (5'-R(*GP*GP*AP*C)-D(P*TP*TP*CP*GP*GP*TP*CP*C)-3')
Authors:Denisov, A.Y, Gehring, K.
Deposit date:2000-12-11
Release date:2001-11-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids.
Nucleic Acids Res., 29, 2001
5DQG
DownloadVisualize
BU of 5dqg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dAMPNPP Opposite O4-Ethylthymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLG
DownloadVisualize
BU of 5dlg by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Methylhymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5DB)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-04
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.351 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DQH
DownloadVisualize
BU of 5dqh by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dGMPNPP Opposite O4-Ethylthymidine
Descriptor: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(5EJ)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-14
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
5DLF
DownloadVisualize
BU of 5dlf by Molmil
Crystal Structure of Human DNA Polymerase Eta Inserting dATP Opposite O4-Methylhymidine
Descriptor: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Patra, A, OFlaherty, D.K, Egli, M.
Deposit date:2015-09-04
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Lesion Orientation ofO4-Alkylthymidine Influences Replication by Human DNA Polymeraseeta.
Chem Sci, 7, 2016
4F02
DownloadVisualize
BU of 4f02 by Molmil
Crystal structure of the PABP-binding site of eIF4G in complex with RRM1-2 of PABP and poly(A)
Descriptor: Eukaryotic translation initiation factor 4 gamma 1, Polyadenylate-binding protein 1, RNA (5'-R(*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3')
Authors:Safaee, N, Kozlov, G, Gehring, K.B.
Deposit date:2012-05-03
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F26
DownloadVisualize
BU of 4f26 by Molmil
Crystal structure of the second RRM domain of human PABPC1 a pH 9.0
Descriptor: Polyadenylate-binding protein 1
Authors:Kozlov, G, Safaee, N, Gehring, K.
Deposit date:2012-05-07
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012
4F25
DownloadVisualize
BU of 4f25 by Molmil
Crystal structure of the second RRM domain of human PABPC1 at pH 6.0
Descriptor: Polyadenylate-binding protein 1
Authors:Kozlov, G, Safaee, N, Gehring, K.
Deposit date:2012-05-07
Release date:2012-08-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G.
Mol.Cell, 48, 2012

226262

PDB entries from 2024-10-16

PDB statisticsPDBj update infoContact PDBjnumon