5EIZ
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5V73
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6HS3
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4P01
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4P0H
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4P7M
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4P7S
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4PKZ
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4PLU
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4PKK
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5BSJ
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5BS9
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5BSC
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5BSI
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8SPN
| Crystal structure of macrophage migration inhibitory factor in complex with T614 | Descriptor: | GLYCEROL, ISOPROPYL ALCOHOL, Iguratimod, ... | Authors: | Pantouris, G, Lolis, E. | Deposit date: | 2023-05-03 | Release date: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose. Mol Med, 30, 2024
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2HPW
| Green fluorescent protein from Clytia gregaria | Descriptor: | Green fluorescent protein | Authors: | Stepanyuk, G, Liu, Z.J, Vysotski, S.E, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2006-07-17 | Release date: | 2006-09-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of Green Fluorescent Protein from Clytia Gregaria at 1.55 A resolution To be Published
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1JPY
| Crystal structure of IL-17F | Descriptor: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Hymowitz, S.G, Filvaroff, E.H, Yin, J, Lee, J, Cai, L, Risser, P, Maruoka, M, Mao, W, Foster, J, Kelley, R, Pan, G, Gurney, A.L, de Vos, A.M, Starovasnik, M.A. | Deposit date: | 2001-08-03 | Release date: | 2001-09-28 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J., 20, 2001
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1ONJ
| Crystal structure of Atratoxin-b from Chinese cobra venom of Naja atra | Descriptor: | Cobrotoxin b, SULFATE ION | Authors: | Lou, X, Tu, X, Pan, G, Xu, C, Fan, R, Lu, W, Deng, W, Rao, P, Teng, M, Niu, L. | Deposit date: | 2003-02-28 | Release date: | 2004-02-28 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.555 Å) | Cite: | Purification, N-terminal sequencing, crystallization and preliminary structural determination of atratoxin-b, a short-chain alpha-neurotoxin from Naja atra venom. Acta Crystallogr.,Sect.D, 59, 2003
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1BFJ
| SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | P85 ALPHA | Authors: | Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. | Deposit date: | 1997-11-18 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
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1BFI
| SOLUTION STRUCTURE OF THE C-TERMINAL SH2 DOMAIN OF THE P85ALPHA REGULATORY SUBUNIT OF PHOSPHOINOSITIDE 3-KINASE, NMR, 30 STRUCTURES | Descriptor: | P85 ALPHA | Authors: | Siegal, G, Davis, B, Kristensen, S.M, Sankar, A, Linacre, J, Stein, R.C, Panayotou, G, Waterfield, M.D, Driscoll, P.C. | Deposit date: | 1997-11-18 | Release date: | 1998-02-25 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. J.Mol.Biol., 276, 1998
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8DBB
| Crystal structure of DDT with the selective inhibitor 2,5-Pyridinedicarboxylic Acid | Descriptor: | CITRIC ACID, D-dopachrome decarboxylase, pyridine-2,5-dicarboxylic acid | Authors: | Parkins, A, Banumathi, S, Pantouris, G. | Deposit date: | 2022-06-14 | Release date: | 2023-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | 2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase. Structure, 31, 2023
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6C23
| Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | Authors: | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | Deposit date: | 2018-01-05 | Release date: | 2018-01-24 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
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6C24
| Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Extended Active State | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, JARID2-substrate, ... | Authors: | Kasinath, V, Faini, M, Poepsel, S, Reif, D, Feng, A, Stjepanovic, G, Aebersold, R, Nogales, E. | Deposit date: | 2018-01-06 | Release date: | 2018-01-24 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science, 359, 2018
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6Q6C
| Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | Descriptor: | 1,2-ETHANEDIOL, Kunitz-type conkunitzin-S1, NITRATE ION, ... | Authors: | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | Deposit date: | 2018-12-10 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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6Q61
| Pore-modulating toxins exploit inherent slow inactivation to block K+ channels | Descriptor: | Kunitz-type conkunitzin-S1, SULFATE ION | Authors: | Karbat, I, Gueta, H, Fine, S, Szanto, T, Hamer-Rogotner, S, Dym, O, Frolow, F, Gordon, D, Panyi, G, Gurevitz, M, Reuveny, E. | Deposit date: | 2018-12-10 | Release date: | 2019-08-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Pore-modulating toxins exploit inherent slow inactivation to block K+channels. Proc.Natl.Acad.Sci.USA, 116, 2019
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