4P7S

Crystal structure of PfMIF in complex with 4-(3-methoxy-5-methylphenoxy)-2-(4-methoxyphenyl)-6-methylpyridine

Summary for 4P7S

Entry DOI	10.2210/pdb4p7s/pdb
Related	4P7M
Descriptor	Macrophage migration inhibitory factor-like protein, 4-(3-methoxy-5-methylphenoxy)-2-(4-methoxyphenyl)-6-methylpyridine (2 entities in total)
Functional Keywords	inhibitor, malaria complex active site, cytokine-inhibitor complex, cytokine/inhibitor
Biological source	Plasmodium falciparum
Total number of polymer chains	3
Total formula weight	38669.46
Authors	Pantouris, G.,Lolis, E. (deposition date: 2014-03-27, release date: 2014-10-15, Last modification date: 2023-12-27)
Primary citation	Pantouris, G.,Rajasekaran, D.,Garcia, A.B.,Ruiz, V.G.,Leng, L.,Jorgensen, W.L.,Bucala, R.,Lolis, E.J. Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors. J.Med.Chem., 57:8652-8656, 2014 Cited by PubMed: 25268646 DOI: 10.1021/jm501168q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.87 Å)

Structure validation