4P7M
Crystal structure of Plasmodium falciparum MIF in complex with 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol
Summary for 4P7M
| Entry DOI | 10.2210/pdb4p7m/pdb |
| Related | 4P7S |
| Descriptor | Macrophage migration inhibitory factor-like protein, 3-[(2-methyl-6-phenylpyridin-4-yl)oxy]phenol (2 entities in total) |
| Functional Keywords | malaria, inhibitor, active site, complex, cytokine-inhibitor complex, cytokine/inhibitor |
| Biological source | Plasmodium falciparum |
| Total number of polymer chains | 3 |
| Total formula weight | 38275.98 |
| Authors | Pantouris, G.,Lolis, E. (deposition date: 2014-03-27, release date: 2014-10-15, Last modification date: 2023-12-27) |
| Primary citation | Pantouris, G.,Rajasekaran, D.,Garcia, A.B.,Ruiz, V.G.,Leng, L.,Jorgensen, W.L.,Bucala, R.,Lolis, E.J. Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors. J.Med.Chem., 57:8652-8656, 2014 Cited by PubMed: 25268646DOI: 10.1021/jm501168q PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
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