7W0G
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![BU of 7w0g by Molmil](/molmil-images/mine/7w0g) | Human PPAR delta ligand binding domain in complex with a synthetic agonist H11 | Descriptor: | 2-[2,6-dimethyl-4-[[5-oxidanylidene-4-[4-(trifluoromethyloxy)phenyl]-1,2,4-triazol-1-yl]methyl]phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta | Authors: | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | Deposit date: | 2021-11-18 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.443 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPAR alpha / delta Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. J.Med.Chem., 65, 2022
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1WQE
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![BU of 1wqe by Molmil](/molmil-images/mine/1wqe) | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | Descriptor: | OmTx3 | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | Deposit date: | 2004-09-28 | Release date: | 2005-01-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochem.J., 388, 2005
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1WQC
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![BU of 1wqc by Molmil](/molmil-images/mine/1wqc) | An unusual fold for potassium channel blockers : NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | Descriptor: | OmTx1 | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | Deposit date: | 2004-09-27 | Release date: | 2005-01-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochem.J., 388, 2005
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4NFT
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![BU of 4nft by Molmil](/molmil-images/mine/4nft) | Crystal structure of human lnkH2B-h2A.Z-Anp32e | Descriptor: | Acidic leucine-rich nuclear phosphoprotein 32 family member E, Histone H2B type 2-E, Histone H2A.Z | Authors: | Shan, S, Pan, L, Mao, Z, Wang, W, Sun, J, Dong, Q, Liang, X, Ding, X, Chen, S, Dai, L, Zhang, Z, Zhu, B, Zhou, Z. | Deposit date: | 2013-11-01 | Release date: | 2014-04-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Anp32e, a higher eukaryotic histone chaperone directs preferential recognition for H2A.Z Cell Res., 24, 2014
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8W6C
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![BU of 8w6c by Molmil](/molmil-images/mine/8w6c) | CryoEM structure of NaDC1 with Citrate | Descriptor: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CHOLESTEROL HEMISUCCINATE, CITRIC ACID, ... | Authors: | Chi, X, Chen, Y, Li, Y, Dai, L, Zhang, Y, Shen, Y, Chen, Y, Shi, T, Yang, H, Wang, Z, Yan, R. | Deposit date: | 2023-08-28 | Release date: | 2024-04-17 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of the human NaS1 and NaDC1 transporters revealed the elevator transport and allosteric regulation mechanism. Sci Adv, 10, 2024
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8H7O
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![BU of 8h7o by Molmil](/molmil-images/mine/8h7o) | Crystal structure of aqualigase | Descriptor: | CALCIUM ION, ISOPROPYL ALCOHOL, Subtilisin | Authors: | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-10-20 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of aqualigase To Be Published
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8H7P
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![BU of 8h7p by Molmil](/molmil-images/mine/8h7p) | Crystal structure of aqualigase bound with Suc-AAPF | Descriptor: | 5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE, CALCIUM ION, Subtilisin, ... | Authors: | Li, H, Ma, M.Z, Zhang, L.J, Dai, L, Chen, C.-C, Guo, R.-T. | Deposit date: | 2022-10-20 | Release date: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structure of aqualigase bound with Suc-AAPF To Be Published
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5GZO
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![BU of 5gzo by Molmil](/molmil-images/mine/5gzo) | Structure of neutralizing antibody bound to Zika envelope protein | Descriptor: | Antibody heavy chain, Antibody light chain, Genome polyprotein | Authors: | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | Deposit date: | 2016-09-29 | Release date: | 2017-01-18 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.755 Å) | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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5GZN
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![BU of 5gzn by Molmil](/molmil-images/mine/5gzn) | Structure of neutralizing antibody bound to Zika envelope protein | Descriptor: | Antibody Heavy chain, Antibody light chain, Genome polyprotein | Authors: | Wang, Q, Yang, H, Liu, X, Dai, L, Ma, T, Qi, J, Wong, G, Peng, R, Liu, S, Li, J, Li, S, Song, J, Liu, J, He, J, Yuan, H, Xiong, Y, Liao, Y, Li, J, Yang, J, Tong, Z, Griffin, B, Bi, Y, Liang, M, Xu, X, Cheng, G, Wang, P, Qiu, X, Kobinger, G, Shi, Y, Yan, J, Gao, G.F. | Deposit date: | 2016-09-29 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular determinants of human neutralizing antibodies isolated from a patient infected with Zika virus Sci Transl Med, 8, 2016
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8WNS
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![BU of 8wns by Molmil](/molmil-images/mine/8wns) | Cryo EM map of SLC7A10 in the apo state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1 | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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8WNT
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![BU of 8wnt by Molmil](/molmil-images/mine/8wnt) | Cryo EM map of SLC7A10 with L-Alanine substrate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALANINE, ... | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.42 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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8WNY
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![BU of 8wny by Molmil](/molmil-images/mine/8wny) | Cryo EM map of SLC7A10-SLC3A2 complex in the D-serine bound state | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Amino acid transporter heavy chain SLC3A2, Asc-type amino acid transporter 1, ... | Authors: | Li, Y.N, Guo, Y.Y, Dai, L, Yan, R.H. | Deposit date: | 2023-10-06 | Release date: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structure of the human Asc-1 transporter complex. Nat Commun, 15, 2024
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2JOO
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![BU of 2joo by Molmil](/molmil-images/mine/2joo) | The NMR Solution Structure of Recombinant RGD-hirudin | Descriptor: | Hirudin variant-1 | Authors: | Song, X, Mo, W, Liu, X, Yan, X, Song, H, Dai, L. | Deposit date: | 2007-03-14 | Release date: | 2008-03-18 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The NMR solution structure of recombinant RGD-hirudin Biochem.Biophys.Res.Commun., 360, 2007
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1WMT
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![BU of 1wmt by Molmil](/molmil-images/mine/1wmt) | Scorpion toxin (IsTX) from Opisthacanthus madagascariensis | Descriptor: | IsTX | Authors: | Yamaji, N, Dai, L, Sugase, K, Andriantsiferana, M, Nakajima, T, Iwashita, T. | Deposit date: | 2004-07-20 | Release date: | 2004-10-19 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of IsTX: A male scorpion toxin from Opisthacanthus madagascariensis (Ischnuridae) Eur.J.Biochem., 271, 2004
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1WQD
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![BU of 1wqd by Molmil](/molmil-images/mine/1wqd) | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | Descriptor: | OmTx2 | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | Deposit date: | 2004-09-28 | Release date: | 2005-01-18 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis Biochem.J., 388, 2005
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8JI4
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![BU of 8ji4 by Molmil](/molmil-images/mine/8ji4) | Crystal structure of AetD in complex with 5-bromo-L-tryptophan | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-bromo-L-tryptophan, AetD, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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8JI5
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![BU of 8ji5 by Molmil](/molmil-images/mine/8ji5) | Crystal structure of AetD in complex with 5-bromo-L-tryptophan and two Fe2+ | Descriptor: | 5-bromo-L-tryptophan, AetD, FE (II) ION, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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8JI3
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![BU of 8ji3 by Molmil](/molmil-images/mine/8ji3) | Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan and two Fe2+ | Descriptor: | (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, AetD, FE (II) ION, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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8JI6
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![BU of 8ji6 by Molmil](/molmil-images/mine/8ji6) | Crystal structure of AetD in complex with L-tryptophan | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AetD, FE (II) ION, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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8JI2
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![BU of 8ji2 by Molmil](/molmil-images/mine/8ji2) | Crystal structure of AetD in complex with 5,7-dibromo-L-tryptophan | Descriptor: | (2S)-2-azanyl-3-[5,7-bis(bromanyl)-1H-indol-3-yl]propanoic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, AetD, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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8JI7
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![BU of 8ji7 by Molmil](/molmil-images/mine/8ji7) | Crystal structure of AetD in complex with L-tryptophan and two Fe2+ | Descriptor: | AetD, FE (II) ION, NICKEL (II) ION, ... | Authors: | Li, H, Dai, L, Zheng, H.B, Chen, C.-C, Guo, R.-T. | Deposit date: | 2023-05-26 | Release date: | 2023-11-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | The structural and functional investigation into an unusual nitrile synthase. Nat Commun, 14, 2023
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6J5G
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![BU of 6j5g by Molmil](/molmil-images/mine/6j5g) | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | Descriptor: | Envelope protein E, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.291 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J5C
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![BU of 6j5c by Molmil](/molmil-images/mine/6j5c) | Louping ill virus envelope protein | Descriptor: | Envelope protein E | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J5D
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![BU of 6j5d by Molmil](/molmil-images/mine/6j5d) | Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III | Descriptor: | Envelope, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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6J5F
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![BU of 6j5f by Molmil](/molmil-images/mine/6j5f) | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein Domain III | Descriptor: | Envelope protein, antibody heavy chain, antibody light chain | Authors: | Yang, X, Qi, J, Peng, R, Dai, L, Gould, E.A, Tien, P, Gao, G.F. | Deposit date: | 2019-01-10 | Release date: | 2019-02-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Molecular Basis of a Protective/Neutralizing Monoclonal Antibody Targeting Envelope Proteins of both Tick-Borne Encephalitis Virus and Louping Ill Virus. J. Virol., 93, 2019
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