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3OW9
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BU of 3ow9 by Molmil
Structure of an amyloid forming peptide KLVFFA from amyloid beta, alternate polymorph II
Descriptor: KLVFFA hexapeptide segment from Amyloid beta
Authors:Landau, M, Eisenberg, D.
Deposit date:2010-09-17
Release date:2011-08-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular basis for amyloid-{beta} polymorphism.
Proc.Natl.Acad.Sci.USA, 108, 2011
3FTH
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BU of 3fth by Molmil
NFLVHSS segment from Islet Amyloid Polypeptide (IAPP or Amylin)
Descriptor: NFLVHSS heptapeptide from Islet Amyloid Polypeptide, SULFATE ION
Authors:Wiltzius, J.J.W, Sawaya, M.R, Eisenberg, D.
Deposit date:2009-01-13
Release date:2009-06-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Molecular mechanisms for protein-encoded inheritance
Nat.Struct.Mol.Biol., 16, 2009
1LGR
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BU of 1lgr by Molmil
INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM
Descriptor: ADENOSINE MONOPHOSPHATE, GLUTAMINE SYNTHETASE, MANGANESE (II) ION
Authors:Liaw, S.-H, Eisenberg, D.
Deposit date:1994-08-05
Release date:1994-11-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Interactions of nucleotides with fully unadenylylated glutamine synthetase from Salmonella typhimurium.
Biochemistry, 33, 1994
3NVE
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BU of 3nve by Molmil
MMHFGN segment 138-143 from Syrian Hamster prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
5KMZ
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BU of 5kmz by Molmil
Solution NMR structure of Tetrahymena telomerase RNA pseudoknot
Descriptor: Telomerase RNA pseudoknot
Authors:Cash, D.D, Feigon, J.
Deposit date:2016-06-27
Release date:2016-10-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions.
Science, 350, 2015
3NVF
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BU of 3nvf by Molmil
IIHFGS segment 138-143 from human prion
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
3NVG
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BU of 3nvg by Molmil
MIHFGN segment 137-142 from mouse prion
Descriptor: Major prion protein
Authors:Apostol, M.I, Sawaya, M.R, Eisenberg, D.
Deposit date:2010-07-08
Release date:2011-03-02
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Atomic structures suggest determinants of transmission barriers in Mammalian prion disease.
Biochemistry, 50, 2011
1LOJ
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BU of 1loj by Molmil
Crystal structure of a Methanobacterial Sm-like archaeal protein (SmAP1) bound to uridine-5'-monophosphate (UMP)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, URIDINE, URIDINE-5'-MONOPHOSPHATE, ...
Authors:Mura, C, Kozhukhovsky, A, Eisenberg, D.
Deposit date:2002-05-06
Release date:2003-03-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The oligomerization and ligand-binding properties of Sm-like archaeal proteins (SmAPs)
Protein Sci., 12, 2003
1M5Q
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BU of 1m5q by Molmil
Crystal structure of a novel Sm-like archaeal protein from Pyrobaculum aerophilum
Descriptor: ACETIC ACID, CADMIUM ION, GLYCEROL, ...
Authors:Mura, C, Phillips, M, Kozhukhovsky, A, Eisenberg, D.
Deposit date:2002-07-09
Release date:2003-03-18
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and assembly of an augmented Sm-like archaeal protein 14-mer
Proc.Natl.Acad.Sci.USA, 100, 2003
5CY5
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BU of 5cy5 by Molmil
Crystal structure of the T33-51H designed self-assembling protein tetrahedron
Descriptor: T33-51H-A, T33-51H-B
Authors:Cannon, K.A, Cascio, D, Park, R, Boyken, S, King, N, Yeates, T.O.
Deposit date:2015-07-30
Release date:2016-08-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering.
Protein Sci., 29, 2020
4IOD
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BU of 4iod by Molmil
Preliminary structural investigations of a malarial protein secretion system.
Descriptor: Malarial CLP B2 atpase/HSP101 protein, SULFATE ION
Authors:Egea, P.F.
Deposit date:2013-01-07
Release date:2014-04-23
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
5W50
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BU of 5w50 by Molmil
Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-06-13
Release date:2018-02-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WIA
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BU of 5wia by Molmil
Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-18
Release date:2018-04-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.002 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
4IRF
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BU of 4irf by Molmil
Preliminary structural investigations of a malarial protein secretion system
Descriptor: MALARIAL CLPB2 ATPASE/HSP101 PROTEIN
Authors:Egea, P.F.
Deposit date:2013-01-14
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
Protein Sci., 24, 2015
5WHN
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BU of 5whn by Molmil
Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317
Descriptor: Segment of TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-17
Release date:2018-04-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5W7V
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BU of 5w7v by Molmil
CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Ge, P, Eisenberg, D.S.
Deposit date:2017-06-20
Release date:2018-03-14
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WHP
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BU of 5whp by Molmil
Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317
Descriptor: Segment of TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-17
Release date:2018-05-23
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WIQ
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BU of 5wiq by Molmil
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
Descriptor: TAR DNA-binding protein 43
Authors:Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2017-07-19
Release date:2018-04-18
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CF4
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BU of 6cf4 by Molmil
Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317
Descriptor: NFGTFS
Authors:Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-13
Release date:2018-05-23
Last modified:2024-11-06
Method:ELECTRON CRYSTALLOGRAPHY (0.75 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6WLA
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BU of 6wla by Molmil
Antigen binding fragment of ch128.1
Descriptor: Fab ch128.1 heavy chain, Fab ch128.1 light chain, GLYCEROL
Authors:Helguera, G, Rodriguez, J.A, Sawaya, M, Cascio, D, Zink, S, Ziegenbein, J, Short, C.
Deposit date:2020-04-18
Release date:2021-03-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Host receptor-targeted therapeutic approach to counter pathogenic New World mammarenavirus infections.
Nat Commun, 13, 2022
4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
Descriptor: Alpha-synuclein
Authors:Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
Deposit date:2014-10-06
Release date:2015-08-26
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.854 Å)
Cite:Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
6CB9
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BU of 6cb9 by Molmil
Segment AALQSS from the low complexity domain of TDP-43, residues 328-333
Descriptor: AALQSS
Authors:Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-02
Release date:2018-04-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CEW
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BU of 6cew by Molmil
Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326
Descriptor: AMMAAA
Authors:Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2018-02-12
Release date:2018-04-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
3O7O
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BU of 3o7o by Molmil
Use of synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima
Descriptor: BROMIDE ION, Endoglucanase
Authors:Forse, G.J, Ram, N, Yeates, T.O.
Deposit date:2010-07-30
Release date:2010-12-01
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Synthetic symmetrization in the crystallization and structure determination of CelA from Thermotoga maritima.
Protein Sci., 20, 2011
4QXX
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BU of 4qxx by Molmil
Structure of the amyloid forming peptide GNLVS (residues 26-30) from the eosinophil major basic protein (EMBP)
Descriptor: Bone marrow proteoglycan
Authors:Soriaga, A.B, Soragni, A, Sawaya, M.R, Eisenberg, D.
Deposit date:2014-07-22
Release date:2015-03-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.445 Å)
Cite:Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015

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