4IRF

Preliminary structural investigations of a malarial protein secretion system

Summary for 4IRF

Entry DOI	10.2210/pdb4irf/pdb
Related	4IOD
Descriptor	MALARIAL CLPB2 ATPASE/HSP101 PROTEIN (2 entities in total)
Functional Keywords	malaria, aaa+ atpase clpb chaperone, n-terminal cargo-binding domain, protein translocation and unfolding, parasitophorous vacuole, chaperone
Biological source	Plasmodium falciparum
Total number of polymer chains	2
Total formula weight	34667.54
Authors	Egea, P.F. (deposition date: 2013-01-14, release date: 2014-04-16, Last modification date: 2023-09-20)
Primary citation	AhYoung, A.P.,Koehl, A.,Cascio, D.,Egea, P.F. Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design. Protein Sci., 24:1508-1520, 2015 Cited by PubMed: 26130467 DOI: 10.1002/pro.2739 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation