8G4Y
 
 | | Structure of ZNRF3 ECD bound to peptide MK1-3.6.10 | | Descriptor: | E3 ubiquitin-protein ligase ZNRF3, MK1-3.6.10 | | Authors: | Harris, S.F, Wu, P. | | Deposit date: | 2023-02-10 | | Release date: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.41 Å) | | Cite: | Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.
Cell Chem Biol, 2023
|
|
8GZ3
 | |
5Z5K
 | | Structure of the DCC-Draxin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ... | | Authors: | Liu, Y, Xiao, J, Wang, J. | | Deposit date: | 2018-01-18 | | Release date: | 2018-06-20 | | Last modified: | 2021-03-10 | | Method: | X-RAY DIFFRACTION (2.493 Å) | | Cite: | Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
|
|
7DWB
 | | Human Pannexin1 model | | Descriptor: | Pannexin-1 | | Authors: | Zhang, S.S, Yang, M.J. | | Deposit date: | 2021-01-17 | | Release date: | 2021-05-26 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis.
Cell Discov, 7, 2021
|
|
1VIO
 | | Crystal structure of pseudouridylate synthase | | Descriptor: | 1,4-BUTANEDIOL, Ribosomal small subunit pseudouridine synthase A | | Authors: | Structural GenomiX | | Deposit date: | 2003-12-01 | | Release date: | 2003-12-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Structure of the pseudouridine synthase RsuA from Haemophilus influenzae.
Acta Crystallogr.,Sect.F, 61, 2005
|
|
1VJE
 | |
1VHN
 | |
1VI7
 | | Crystal structure of an hypothetical protein | | Descriptor: | Hypothetical protein yigZ | | Authors: | Structural GenomiX | | Deposit date: | 2003-12-01 | | Release date: | 2003-12-30 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of YIGZ, a conserved hypothetical protein from Escherichia coli k12 with a novel fold
Proteins, 55, 2004
|
|
7VQ2
 | | Structure of Apo-hsTRPM2 channel TM domain | | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | | Authors: | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | | Deposit date: | 2021-10-18 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
|
|
7VQ1
 | | Structure of Apo-hsTRPM2 channel | | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | | Authors: | Yu, X.F, Xie, Y, Zhang, X.K, Ma, C, Guo, J.T, Yang, F, Yang, W. | | Deposit date: | 2021-10-18 | | Release date: | 2021-12-22 | | Method: | ELECTRON MICROSCOPY (3.76 Å) | | Cite: | Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.
Cell Rep, 37, 2021
|
|
3HGF
 | | Expression, purification, spectroscopical and crystallographical studies of segments of the nucleotide binding domain of the reticulocyte binding protein Py235 of Plasmodium yoelii | | Descriptor: | Rhoptry protein fragment | | Authors: | Gruber, A, Manimekalai, M.S.S, Balakrishna, A.M, Hunke, C, Jeyakanthan, J, Preiser, P.R, Gruber, G. | | Deposit date: | 2009-05-13 | | Release date: | 2010-02-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (4 Å) | | Cite: | Structural determination of functional units of the nucleotide binding domain (NBD94) of the reticulocyte binding protein Py235 of Plasmodium yoelii
Plos One, 5, 2010
|
|
7X1R
 | | Cryo-EM structure of human thioredoxin reductase bound by Au | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, Thioredoxin reductase 1, ... | | Authors: | He, Z.S, Cao, P, Cao, S.H, He, B, Jiang, H.D, Gong, Y, Gao, X.Y. | | Deposit date: | 2022-02-24 | | Release date: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Au4 cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189
Nano Today, 47, 2022
|
|
7DZ3
 | | Crystal structures of D-allulose 3-epimerase with D-fructose from Sinorhizobium fredii | | Descriptor: | D-fructose, D-tagatose 3-epimerase, MAGNESIUM ION | | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | Deposit date: | 2021-01-23 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
|
|
7DZ4
 | | Crystal structures of D-allulose 3-epimerase with D-tagatose from Sinorhizobium fredii | | Descriptor: | D-tagatose, D-tagatose 3-epimerase, MAGNESIUM ION | | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | Deposit date: | 2021-01-23 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
|
|
7DZ5
 | | Crystal structures of D-allulose 3-epimerase with D-sorbose from Sinorhizobium fredii | | Descriptor: | D-sorbose, D-tagatose 3-epimerase, MAGNESIUM ION, ... | | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | Deposit date: | 2021-01-23 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
|
|
7DZ2
 | | Crystal structures of D-allulose 3-epimerase from Sinorhizobium fredii | | Descriptor: | D-tagatose 3-epimerase, MAGNESIUM ION, SULFATE ION | | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | Deposit date: | 2021-01-23 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
|
|
7DZ6
 | | Crystal structures of D-allulose 3-epimerase with D-allulose from Sinorhizobium fredii | | Descriptor: | D-psicose, D-tagatose 3-epimerase, MAGNESIUM ION | | Authors: | Zhu, Z.L, Miyakawa, T, Tanokura, M, Lu, F.P, Qin, H.-M. | | Deposit date: | 2021-01-23 | | Release date: | 2022-08-03 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Substantial Improvement of an Epimerase for the Synthesis of D-Allulose by Biosensor-Based High-Throughput Microdroplet Screening
Angew.Chem.Int.Ed.Engl., 2023
|
|
7DQA
 | | Cryo-EM structure of SARS-CoV2 RBD-ACE2 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, CHLORIDE ION, ... | | Authors: | Wang, J, Lan, J, Wang, X.Q, Wang, H.W. | | Deposit date: | 2020-12-22 | | Release date: | 2021-12-29 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Reduced graphene oxide membrane as supporting film for high-resolution cryo-EM
Biophys Rep, 7, 2022
|
|
7YFK
 | | The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin | | Descriptor: | Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 | | Authors: | Xia, Y, Yao, D, Huang, C, Cao, Y. | | Deposit date: | 2022-07-08 | | Release date: | 2023-06-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Nat Commun, 14, 2023
|
|
7WYP
 | | Structure of the SARS-COV-2 main protease with EN102 inhibitor | | Descriptor: | 3C-like proteinase, N-(1,3-benzothiazol-2-ylmethyl)-N-cyclopropyl-prop-2-enamide | | Authors: | Qin, B, Hou, P, Gao, X, Cui, S. | | Deposit date: | 2022-02-16 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
|
|
7WYL
 | | Structure of the EV71 3Cpro with 337 inhibitor | | Descriptor: | 3C protein, N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide | | Authors: | Qin, B, Hou, P, Gao, X, Cui, S. | | Deposit date: | 2022-02-16 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
|
|
7WYO
 | | Structure of the EV71 3Cpro with 338 inhibitor | | Descriptor: | 3C protein, N-methyl-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylmethyl)prop-2-enamide | | Authors: | Qin, B, Hou, P, Gao, X, Cui, S. | | Deposit date: | 2022-02-16 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.402 Å) | | Cite: | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
|
|
7WYM
 | | Structure of the SARS-COV-2 main protease with 337 inhibitor | | Descriptor: | 3C-like proteinase nsp5, N-methyl-N-[[4-(trifluoromethyl)-1,3-thiazol-2-yl]methyl]prop-2-enamide | | Authors: | Qin, B, Hou, P, Gao, X, Cui, S. | | Deposit date: | 2022-02-16 | | Release date: | 2022-06-22 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease.
Acta Pharm Sin B, 12, 2022
|
|
