7WYP
Structure of the SARS-COV-2 main protease with EN102 inhibitor
Summary for 7WYP
Entry DOI | 10.2210/pdb7wyp/pdb |
Descriptor | 3C-like proteinase, N-(1,3-benzothiazol-2-ylmethyl)-N-cyclopropyl-prop-2-enamide (3 entities in total) |
Functional Keywords | structure of the sars-cov-2 main protease with en102 inhibitor, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 68167.77 |
Authors | |
Primary citation | Qin, B.,Craven, G.B.,Hou, P.,Chesti, J.,Lu, X.,Child, E.S.,Morgan, R.M.L.,Niu, W.,Zhao, L.,Armstrong, A.,Mann, D.J.,Cui, S. Acrylamide fragment inhibitors that induce unprecedented conformational distortions in enterovirus 71 3C and SARS-CoV-2 main protease. Acta Pharm Sin B, 12:3924-3933, 2022 Cited by PubMed: 35702321DOI: 10.1016/j.apsb.2022.06.002 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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