7VQ2

Structure of Apo-hsTRPM2 channel TM domain

Summary for 7VQ2

• Entry DOI: 10.2210/pdb7vq2/pdb
• EMDB information: 32083
• Descriptor: Transient receptor potential cation channel subfamily M member 2 (1 entity in total)
• Functional Keywords: channel, trpm2, selectivity filter, tm domain, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 4
• Total formula weight: 163869.59

Authors

Yu, X.F.,Xie, Y.,Zhang, X.K.,Ma, C.,Guo, J.T.,Yang, F.,Yang, W. (deposition date: 2021-10-18, release date: 2021-12-22)

• Primary citation: Yu, X.,Xie, Y.,Zhang, X.,Ma, C.,Liu, L.,Zhen, W.,Xu, L.,Zhang, J.,Liang, Y.,Zhao, L.,Gao, X.,Yu, P.,Luo, J.,Jiang, L.H.,Nie, Y.,Yang, F.,Guo, J.,Yang, W.; Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel.; Cell Rep, 37:110025-110025, 2021; PubMed: 34788616; DOI: 10.1016/j.celrep.2021.110025

Experimental method

ELECTRON MICROSCOPY (3.68 Å)