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6UDP

Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Filament assembly interface reconstruction.

Summary for 6UDP
Entry DOI10.2210/pdb6udp/pdb
Related6U8E 6U8N 6U8R 6U8S 6U9O 6UA2 6UA4 6UA5 6UAJ 6UC2 6UDO
EMDB information20687 20688 20690 20691 20701 20704 20705 20706 20707 20709 20716 20718 20720 20722 20723 20725 20741 20742
DescriptorInosine-5'-monophosphate dehydrogenase 2, INOSINIC ACID (2 entities in total)
Functional Keywordsmetabolism, filament, allostery, adenine, guanine, biosynthetic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total formula weight454629.65
Authors
Johnson, M.C.,Kollman, J.M. (deposition date: 2019-09-19, release date: 2020-03-25, Last modification date: 2024-03-20)
Primary citationJohnson, M.C.,Kollman, J.M.
Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation.
Elife, 9:-, 2020
Cited by
PubMed: 31999252
DOI: 10.7554/eLife.53243
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (2.95 Å)
Structure validation

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