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6UDP

Human IMPDH2 treated with ATP, IMP, and 20 mM GTP. Filament assembly interface reconstruction.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, B, C, D, E...)
Inosine-5'-monophosphate dehydrogenase 2polymer51956480.58UniProt (P12268)
Pfam (PF00478)
Pfam (PF00571)
Homo sapiens (Human)IMPDH 2,IMPDH-II
2I, J, K, L, M...
(A, B, C, D, E...)
INOSINIC ACIDnon-polymer348.28Chemie (IMP)
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 514 (UniProt: P12268)
PDBExternal DatabaseDetails
Ser -4-expression tag
Glu -3-expression tag
Phe -2-expression tag
Glu -1-expression tag
Leu 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight451844.0
Non-Polymers*Number of molecules8
Total formula weight2785.6
All*Total formula weight454629.6
*Water molecules are not included.

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PDB entries from 2025-08-27

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